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Fistula clinical trials

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NCT ID: NCT05906550 Recruiting - Clinical trials for Hemodialysis Access Failure

Flow Dysfunction of Hemodialysis Vascular Access

FLOW
Start date: November 1, 2021
Phase: N/A
Study type: Interventional

The FLOW trial evaluates the follow-up of the vascular access for hemodialysis. In current clinical care, vascular access flow volume is periodically assessed to detect and treat asymptomatic stenosis. The FLOW trial will determine whether it is safe to abandon this practice of active surveillance. Vascular access stenosis will then be treated only when clinical problems of flow dysfunction occur during hemodialysis. The investigators expect that the intervention rate and medical costs will be reduced by 40% when correction of vascular access stenosis is triggered by clinically apparent access dysfunction rather than asymptomatic flow reduction.

NCT ID: NCT05899569 Suspended - Clinical trials for Complex Anal Fistulas

Fistura® Procedure for the Treatment of Complex Anal Fistulas

Start date: October 15, 2023
Phase: N/A
Study type: Interventional

This study aims to evaluate the healing rate of complex fistulas using radiofrequency (Fistura® procedure), in a prospective, interventional, monocenter, single-arm design.

NCT ID: NCT05852457 Recruiting - Fistula Clinical Trials

Evaluation of the Clinical Utility of Endoscopic Closure Using a Dual Action Tissue (DAT) Clip

Start date: August 31, 2022
Phase:
Study type: Observational

This study is designed as a multicenter prospective data recording study to document the performance of the DAT clip as part of standard medical care of patients. No experimental interventions will be performed.

NCT ID: NCT05847101 Not yet recruiting - Clinical trials for Tracheo Esophageal Fistula

Outcome Predictors of Trachea-esophageal Fistula

Start date: June 2023
Phase:
Study type: Observational

In the present study, the investigator aim to evaluate the prevalence, factors affecting outcome and the outcome of neonates with tracheoesophageal fistula.

NCT ID: NCT05843877 Not yet recruiting - Clinical trials for Periampullary Cancer

Pancreatic Head Resection or Total Pancreatectomy With Islet Autotransplantation in Patients With Periampullary Cancer and High Risk Profile for the Development of Postoperative Pancreatic Fistula

XandTX
Start date: June 2024
Phase: Phase 3
Study type: Interventional

The primary objective of this clinical trial is to evaluate whether primary total pancreatectomy with simultaneous islet autotransplantation compared with pancreatic head resection (alone) can reduce perioperative morbidity and time to initiation of adjuvant therapy in patients with a high-risk constellation for pancreatic fistulas.

NCT ID: NCT05836883 Recruiting - Crohn's Disease Clinical Trials

Study of ExoFlo for the Treatment of Perianal Fistulas

Start date: August 28, 2023
Phase: Phase 1/Phase 2
Study type: Interventional

To evaluate the safety and feasibility of ExoFlo as a treatment for Perianal Fistulizing Crohn's Disease.

NCT ID: NCT05834985 Completed - Fistula; Sigmoid Clinical Trials

Endoscopic Management Of Controlled Colo-cutaneous Fistula As A Complication of Acute Sigmoid Diverticulitis: A Randomized Controlled Trial

Start date: December 1, 2020
Phase: N/A
Study type: Interventional

Diverticular disease is a common condition in western countries with relatively uncommon complications[1]. Fistulae complicating diverticulitis are the result of a localized perforation into adjacent viscera, and occur in 4-23% of patients hospitalized for diverticular disease[2]. The types of fistulae include colovesical, colovaginal, colotubal, coloenteric, and colocutaneous fistulae[3]. Colocutaneous fistulae occur very rarely, accounting for 1-4% of the total number of fistulae complicating colonic diverticular disease[4]. Herein we describe a case of a fistula connecting the sigmoid colon with the left flank-lower lumbar area, due to diverticulitis of the sigmoid colon[5]. A new over-the-scope clip system, called OTSC (Ovesco Endoscopy, Tübingen, Germany), appeared on the market about 3 years ago[6]. The system consists of a nitinol clip loaded at the tip of the endoscope that can capture a large amount of tissue and compress the lesion until healed[7]. Results from animal models and initial clinical use support the efficacy of OTSC closure in the treatment of gastrointestinal bleeding; its role in the management of iatrogenic perforations in humans is less defined, and reports on its use in treating colorectal postsurgical leaks and fistulas are anecdotal [8]. Here we report on the use of OTSC in the endoscopic treatment of colo-cutaneous fistula as acomplication of acute diverticultis .

NCT ID: NCT05832476 Completed - Clinical trials for Arteriovenous Fistula Occlusion

O-GlcNac Modified Proteomics Study of the Maturation of Hemodialysis Arteriovenous

Start date: March 28, 2018
Phase:
Study type: Observational [Patient Registry]

We divided into three parts to carry out. Firstly, evidence the pre-existing fibrosis in vein of AVF failure patients. investigation of expression, the role, and the mechanism by which the identified O-GlcNAac proteins promote, maturation of AV fistula. Finally, ddress and compare the proteomics differentiation between failure and maturation of AVF patients.

NCT ID: NCT05809258 Recruiting - Clinical trials for Arteriovenous Fistula

Supraclavicular Versus Axillary Block for Arteriovenous (AV) Fistula Creation

CUGSCAB
Start date: August 7, 2023
Phase: N/A
Study type: Interventional

This study compares the analgesic efficacy of supraclavicular brachial plexus nerve block to axillary nerve block techniques in adults undergoing AV fistula creation. Both these techniques will be done under ultrasound guidance, using the same local anesthetic drug. 120 patients will be included in this study, 60 patients for each technique. This study will help us know better regional anesthesia techniques, the additional need for analgesia/anesthesia, and the recovery rate following either of the blocks for AV fistula surgery. An interim analysis will be done after recruiting 50% of cases (30 cases) in both arms.

NCT ID: NCT05807906 Completed - Clinical trials for Chronic Kidney Diseases

The Effect of Virtual Reality Application on Pain Due to Fistula Puncture in Hemodialysis Patients

Start date: April 17, 2023
Phase: N/A
Study type: Interventional

The aim of this study is to examine the effect of virtual reality application on fistula puncture-related pain (FPi-A) in hemodialysis patients. Hypotheses of the Research: H0-1: Virtual reality application has an effect on fistula puncture-related pain in HD patients. H1-2: Virtual reality application has no effect on fistula puncture-related pain in HD patients. In the study, virtual reality will be applied in the fistula puncture procedure in patients receiving hemodialysis treatment.