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Fever clinical trials

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NCT ID: NCT01094431 Completed - Fever Clinical Trials

Etiology of Uncomplicated Fever in Children <5 in Rural Zanzibar

RDTNEG
Start date: April 2011
Phase: N/A
Study type: Observational

The purpose of this study is to study the most common etiologies of uncomplicated fever diseases among children under five years of age in rural Zanzibar.

NCT ID: NCT01089218 Completed - Pneumonia Clinical Trials

The Impact of Antibiotic Prophylaxis on Incidence of Post-bronchoscopy Fever and Change of Serum Cytokines

Start date: April 2008
Phase: Phase 4
Study type: Interventional

Fever can develop after fiberoptic bronchoscopy (FB) in about 2.5 - 16 % of adult patients. We evaluated the impact of oral amoxicillin/clavulanate (AC) on incidence of postbronchoscopic fever and pneumonia.

NCT ID: NCT01088880 Completed - Clinical trials for Familial Mediterranean Fever

Efficacy and Safety of Canakinumab in Patients With Colchicine Resistant Familial Mediterranean Fever

Start date: April 2010
Phase: Phase 2
Study type: Interventional

Establish the safety and efficacy of 3 months treatment with canakinumab in patients with colchicine resistant Familial Mediterranean Fever.

NCT ID: NCT01070732 Completed - Analgesia Clinical Trials

Paracetamol as Antipyretic and Analgesic Medication

APOTEL01
Start date: January 2010
Phase: Phase 4
Study type: Interventional

The present study is aiming to unravel the clinical efficacy of intravenously administered paracetamol as antipyretic and analgesic medication in various medical conditions.

NCT ID: NCT01064141 Completed - Dengue Fever Clinical Trials

A Study of Dengue Vaccine in Healthy Toddlers Aged 12 to 15 Months in the Philippines

Start date: January 2010
Phase: Phase 2
Study type: Interventional

The purpose of this study is to investigate the potential for co-administration of the first dose of CYD Dengue vaccine with childhood vaccination. Primary Objectives: - To describe the safety of CYD Dengue vaccine after each dose; first dose given alone or coadministered with childhood vaccines. Secondary Objectives: - To describe the immunogenicity of CYD Dengue vaccine after each dose; first dose given alone or co-administered with childhood vaccines.

NCT ID: NCT01060462 Completed - Fever Clinical Trials

Observational Study Investigating the Response Rate of Itraconazole Injection in Treating Immunocompromised Patients

Start date: August 2008
Phase: Phase 4
Study type: Observational

The purpose of this observational study is to examine the rate at which elevated body temperature (fever) is relieved by an itraconazole injection administrated to patients experiencing neutropenic fever . A neutropenic fever is an elevated body temperature that occurs at a time when the patient's white blood cell count is low. White blood cells aid the body's normal defenses against infection, so a fever during this period might make it difficult for the patient to fight infections.

NCT ID: NCT01048801 Completed - Malaria Clinical Trials

Role and Effectiveness of Rapid Diagnostic Tests in Home-based Management of Malaria

ACTUGA2
Start date: March 2010
Phase: N/A
Study type: Interventional

Most malaria deaths occur within 48 hours of onset of symptoms, and in rural areas with poor access to health facilities, home management of malaria (HMM) can improve the timeliness of treatment and reduce malaria mortality by up to 50%. In order to maximize both coverage and impact, ACTs should be deployed in HMM programmes, as well as in formal health facilities. Up to 80% of malaria cases are treated outside the formal health sector and shops are frequently visited as the first (and in some cases only) source of treatment. Strategies to deploy ACTs in Africa thus also need to examine the role of shops in home management and to ensure that drugs sold are appropriate. The current practice of presumptive treatment of any febrile illness as malaria (both at health facilities and in the context of HMM) based solely on clinical symptoms without routine laboratory confirmation, results in significant over-use of antimalarial drugs. With ACT being a more costly regimen, it is important to be more restrictive in its administration and rapid diagnostic tests (RDTs) provide a simple means of confirming malaria diagnosis in remote locations lacking electricity and qualified health staff. This study therefore proposes to evaluate the feasibility, acceptability, and cost-effectiveness of using RDTs to improve malaria diagnosis and treatment by community-based drug distributors.The accuracy of RDTs, and the acceptability of this approach, will be evaluated in both low and high transmission areas.

NCT ID: NCT01043744 Completed - Malaria Clinical Trials

Non-malarial Febrile Illness in Children in Areas of Perennial Malaria Transmission

Start date: January 2010
Phase: N/A
Study type: Interventional

To evaluate the causes of non-malarial febrile illness in children living in an area of perennial malaria transmission and to determine if these children who test negative for malaria by rapid diagnostic test receive any benefit from antimalarial therapy.

NCT ID: NCT01038219 Completed - FEVER Clinical Trials

Reliability of Subjective Assessment of Fever by Parents and Health Care Providers in Children and Adolescents

Start date: May 2010
Phase: N/A
Study type: Observational

Background: Fever is a widespread symptom in many diseases. Therefore, its value and diagnostic importance are well known. Fever in children is one of the common reasons for a visit to the pediatrician. Also, taking temperature is a very simple action and accessible to the general public. Temperature is measured in various parts of the body by using medical equipment. The type of method and thermometer varies according to the patient's age but often temperature is estimated by touch. Temperature measurement serves as a means for monitoring the patient's condition. For that reason, supervision of the body temperature is an important factor in the process of taking medical decisions. Study rationale: the parent is often asked if the child's temperature has been taken. The most frequent answer is: "I didn't measure, but I felt that he has a temperature". The few studies carried out on this subject showed that many parents used touch to evaluate the child's body temperature, especially in infants. Some studies checked the reliability of parents to estimate the child's body temperature by touch only. To the best of our knowledge, the reliability of medical staff (nurses) to estimate the child's body temperature by touch has never been studied. The aim of the current study is to investigate whether parents and nurses correctly estimate the child's body temperature by touch, as compared to thermometer measurement during the pediatric unit's routine work.

NCT ID: NCT01034059 Completed - Neutropenic Fever Clinical Trials

Assessment of sTREM-1 as a Diagnostic Marker in Patients With Neutropenic Fever

Start date: October 2008
Phase: N/A
Study type: Observational

The soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) was an established biomarker useful for infection in non-neutropenic patients. In this study, we tested sTREM-1 in the patients with neutropenic fever. Pro-calcitonin (PCT) and C-reactive protein (CRP) were also measured. We planned to investigate and explore the role of sTREM-1 in early diagnosis of infection in patients with neutropenic fever.