Fetal Growth Retardation Clinical Trial
Official title:
Non-invasive Prenatal Testing of Placental Chromosomal Abnormalities in Fetus With Intrauterine Growth Restriction
The objective of this project is the non-invasive prenatal detection of placenta-limited aneuploidies, in patients whose fetuses have a intrauterine growth restriction below 3rd percentile, in parallel with an amniocentesis. This study will allow the chromosomal study of the placenta in pregnant women whose genetic prenatal diagnosis, made by amniocentesis, does not allow exploring the placental causes of fetal RCIU.
Placental chromosomal aneuploidies will be detected by high-throughput whole genome sequencing of non-cellular DNA present in maternal plasma during pregnancy. The study of the cfDNA will be carried out from a blood sample with the automated solution VERISEQ NIPT (Illumina) using the software illumina VeriSeq v2, allowing the detection of all chromosomal abnormalities. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT05899101 -
The Impact of Opioid and Cannabis Exposure on Fetal Growth
|
||
| Completed |
NCT04502823 -
Management of Fetal Growth Restriction at Term: Angiogenic Factors Versus Feto-placental Doppler
|
N/A | |
| Not yet recruiting |
NCT03625518 -
Mode of Induction in Fetal Growth Restriction and Its Affects on Fetal and Maternal Outcomes
|
Early Phase 1 | |
| Completed |
NCT05176041 -
SLE Therapy Changes in Pregnancy and Relation to Pregnancy Outcome
|
||
| Completed |
NCT02379728 -
Ghana PrenaBelt Trial: A Positional Therapy Device to Reduce Still-Birth
|
N/A | |
| Completed |
NCT01695070 -
Melatonin to Prevent Brain Injury in Unborn Growth Restricted Babies
|
Phase 4 | |
| Completed |
NCT01352234 -
Comparison of Doses of Acetylsalicylic Acid in Women With Previous History of Preeclampsia
|
Phase 4 | |
| Completed |
NCT04289350 -
Day to Day Variation in Fetal Heart Rate Variability
|
||
| Recruiting |
NCT03662178 -
Investigating the Structured Use of Ultrasound Scanning for Fetal Growth
|
||
| Completed |
NCT02590536 -
A Trial Evaluating the Role of Sildenafil in the Treatment of Fetal Growth Restriction
|
Phase 3 | |
| Not yet recruiting |
NCT05029778 -
Arginine + Citrulline as a Supplement for Weight Gain in Fetus With a Decrease in Their Growth Curve
|
Phase 4 | |
| Recruiting |
NCT05576207 -
BEP Supplementation Research in Bangladesh (JiVitA-BEP-IR)
|
N/A | |
| Active, not recruiting |
NCT05160649 -
Effect of Covid 19 Infection on Fetomaternal Outcome
|
||
| Completed |
NCT02280031 -
Effect of Low Dose Aspirin on Birthweight in Twins: The GAP Trial.
|
Phase 2 | |
| Recruiting |
NCT04389099 -
MRI Angiography of Physiological and Pathological Pregnancy Placentas Ex-vivo
|
||
| Recruiting |
NCT06039319 -
Acute Effects of Maternal Exercise and the Growth Restricted Pregnancy
|
||
| Recruiting |
NCT05651347 -
Antenatal Melatonin Supplementation for Neuroprotection in Fetal Growth Restriction
|
Phase 3 | |
| Recruiting |
NCT02336243 -
A Randomized Trial of Docosahexaenoic Acid Supplementation During Pregnancy to Prevent Deep Placentation Disorders
|
Phase 3 | |
| Active, not recruiting |
NCT01594463 -
Routine Ultrasound Screening in the Third Trimester
|
N/A | |
| Completed |
NCT00465634 -
Doppler and Biological Second Trimester Placental Insufficiency Screening
|
N/A |