Efficacy of PRP (Platelet Rich Plasma) Following Arthroscopic

Status Withdrawn

Clinical Trial Summary

Clinical Trial Description

The purpose of this research project is to assess the effectiveness of intra-articular injections of autologous platelet-rich plasma (PRP) after arthroscopic microfracture. Our hypothesis is that platelet-rich plasma will improve patient's clinical outcomes and chondral healing following microfracture performed during femoroacetabular impingement (FAI) hip arthroscopy.

This study has two aims:

1. Evaluate clinical efficacy of intra-articular injections of platelet-rich plasma (PRP) following arthroscopic microfracture.

2. Evaluate if microfracture followed by PRP injections improves chondral healing.

Microfracture has shown good results with chondral lesions of the hip. However, microfracture does not regenerate normal hyaline cartilage. There is growing evidence that PRP can improve articular cartilage healing. Injection of PRP following microfracture may help regeneration to normal hyaline like articular cartilage together with soft tissue healing, thereby improving patients' early and long-term outcomes of chondral healing.

Patients will be randomized to one of two study arms - microfracture with PRP (treatment arm) and microfracture with saline (control arm) in a 1:1 ratio. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02183896
Study type	Interventional
Source	University of Colorado, Denver
Contact
Status	Withdrawn
Phase	N/A
Start date	July 2014
Completion date	July 2015

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT01623843` - Femoroacetabular Impingement RandomiSed Controlled Trial	N/A
Completed	`NCT03669471` - Muscular and Functional Performance in FAIS Patients
Not yet recruiting	`NCT05031390` - the Horsens Aarhus FemoroAcetabular Impingement Syndrome Training Pilot Study	N/A
Active, not recruiting	`NCT05025956` - Senolytic Agent Improve the Benefit of Platelet-Rich Plasma and Losartan	Phase 1/Phase 2
Withdrawn	`NCT02674113` - Regional Anesthesia in Hip Arthroscopy	N/A
Withdrawn	`NCT02260726` - Evaluation of Ultrasound for Detecting Hip Impingement	N/A
Recruiting	`NCT05391204` - Reproducibility of Strength Testing and Functional Testing of the Hip for the Return to Sport of Patients Activated by a Femoroacetabular Impingement: Comparison Between a Group of Patients and a Group of Healthy Controls	N/A
Active, not recruiting	`NCT03891563` - Prospective Evaluation of Sport Activity and the Development of Femoroacetabular Impingement in the Adolescent Hip
Active, not recruiting	`NCT04069507` - Healthy Hip Study: Conservative Management for Pre-arthritic Hip Disorders
Terminated	`NCT03278353` - Fulfillment of Expectations for Patients With FAI Syndrome	N/A
Terminated	`NCT03995290` - 3D Modeling to Improve Hip Arthroscopy Outcomes
Completed	`NCT06082271` - Comparative, Randomized Study on the Anti-inflammatory and Regenerative Efficacy of a New Medical Device (DM) Based on Hydrolyzed Collagen Peptides in Patients With Femoro-acetabular Impingement Undergoing Hip Arthroscopy	N/A
Recruiting	`NCT01621360` - Hip Arthroscopy Versus Conservative Management of Femoroacetabular Impingement	N/A
Completed	`NCT04980209` - The Feasibility and Application of Intraoperative Ultrasound to Evaluate Femoral Head Shaping
Enrolling by invitation	`NCT04988659` - Analysis of Gene Expression in Femoroacetabular Impingement (FAI)
Active, not recruiting	`NCT03494660` - SCP Hip Outcomes Study
Active, not recruiting	`NCT04822571` - Investigating the Reliability of Highly Dynamic 3D Motion Analysis Protocol in Adolescence and Adult Males	N/A
Withdrawn	`NCT02706756` - Conservative Intervention of Femoroacetabular Impingement Syndrome	N/A
Completed	`NCT01814124` - Conservative Management of Femoroacetabular Impingement	N/A
Completed	`NCT01993615` - A Physical Therapy Program Versus Surgery for Femoroacetabular Impingement: Randomized Clinical Trial	N/A

Efficacy of PRP (Platelet Rich Plasma) Following Arthroscopic Microfracture of Chondral Lesions of the Hip

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms