Efficacy of PRP (Platelet Rich Plasma) Following Arthroscopic

Status Withdrawn

Clinical Trial Summary

Clinical Trial Description

The purpose of this research project is to assess the effectiveness of intra-articular injections of autologous platelet-rich plasma (PRP) after arthroscopic microfracture. Our hypothesis is that platelet-rich plasma will improve patient's clinical outcomes and chondral healing following microfracture performed during femoroacetabular impingement (FAI) hip arthroscopy.

This study has two aims:

1. Evaluate clinical efficacy of intra-articular injections of platelet-rich plasma (PRP) following arthroscopic microfracture.

2. Evaluate if microfracture followed by PRP injections improves chondral healing.

Microfracture has shown good results with chondral lesions of the hip. However, microfracture does not regenerate normal hyaline cartilage. There is growing evidence that PRP can improve articular cartilage healing. Injection of PRP following microfracture may help regeneration to normal hyaline like articular cartilage together with soft tissue healing, thereby improving patients' early and long-term outcomes of chondral healing.

Patients will be randomized to one of two study arms - microfracture with PRP (treatment arm) and microfracture with saline (control arm) in a 1:1 ratio. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02183896
Study type	Interventional
Source	University of Colorado, Denver
Contact
Status	Withdrawn
Phase	N/A
Start date	July 2014
Completion date	July 2015

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See also
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Efficacy of PRP (Platelet Rich Plasma) Following Arthroscopic Microfracture of Chondral Lesions of the Hip

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms