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Femoral Fractures clinical trials

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NCT ID: NCT06285981 Recruiting - Clinical trials for Pertrochanteric Fracture of Femur

Retrospective Study Chimaera Long Nail in Adult Patient

Start date: November 27, 2023
Phase:
Study type: Observational

The CHIMERA study intends to evaluate the clinical benefits of the study medical device in the standard clinical practice.

NCT ID: NCT06245993 Recruiting - EOS Clinical Trials

Study of Residuals Deformities After Diaphyseal Femoral Fracture in Children Treated by Skin Traction

FRAFEMKID
Start date: December 15, 2023
Phase:
Study type: Observational

Diaphyseal femoral fracture in children <6 years old are treated by the skin traction technique. As demonstrated by numerous studies, given the significant potential for bone remodeling in young children, remodeling (excluding rotational disorder) allows anatomical correction. The aim of this study is to confirm, via EOS imaging, the absence of residual deformities 3 years after the end of treatment in children treated in Amiens hospital department.

NCT ID: NCT06200402 Recruiting - Clinical trials for Proximal Femoral Fractures

Antibiotic-Loaded Cement Versus Non-Antibiotic-Loaded Cement in Hip Prosthesis Surgery for Proximal Femur Fractures

Start date: July 1, 2023
Phase: N/A
Study type: Interventional

The study aims to determine if antibiotic-loaded cement reduces post-surgery infection rates compared to non-antibiotic cement. The trial involves 450 elderly patients with specific hip fractures, assessing infection incidence, implant stability, and associated costs. This randomized, blinded study is conducted by IRCCS Ospedale San Raffaele.

NCT ID: NCT06135298 Recruiting - Hip Fractures Clinical Trials

FARE Augmentation of Proximal Femoral Fractures With CaS/HA and Systemic ZA

Start date: December 1, 2023
Phase: Phase 4
Study type: Interventional

The goal of this clinical trial is to investigate the new bone formation around a metal device in the femoral head in patients with osteoporotic hip fractures undergoing surgical treatment with nails. These surgeries have a high risk of fixation failure in patients with osteoporosis due to low bone quality. The main question we aim to answer are whether promoting new bone formation around the implant is possible with a bone graft substitute (CERAMENT™ Bone Void Filler) and systemic osteoporosis drug (zoledronic acid) combination, which can strengthen the surgical fixation of the fracture. Participants will consist of patients suffering hip fracture and already scheduled for surgical treatment with a nail. One group will undergo conventional surgery. While the other group will also undergo the same surgery, they will receive CERAMENT™ Bone Void Filler around the implant as a short, extra step during surgery. This will allow the researchers to see whether new bone is formed during a 6-month follow-up.

NCT ID: NCT06032299 Recruiting - Femur Fracture Clinical Trials

Dual Implant Versus Single Implant Distal End of Femur

Start date: April 29, 2024
Phase: N/A
Study type: Interventional

This research study is being conducted to examine the effect of two versus one fixation device for fixation of distal femur fractures.

NCT ID: NCT06028971 Recruiting - Clinical trials for Distal Femur Fracture

Safety and Performance of the Biphasic Plate Distal Femur: A Multicenter Case Series

Start date: January 30, 2024
Phase:
Study type: Observational

The goal of this observational multicenter case series is to assess the safety and performance of the CE-marked "Biphasic Plate Distal Femur" during standard of care.

NCT ID: NCT06018610 Recruiting - Fracture of Femur Clinical Trials

Effectiveness of Relaxation and Massage Methods in Proximal Femur Fractures

Start date: May 18, 2022
Phase: N/A
Study type: Interventional

The study will be conducted with volunteer patients who are followed up by the Orthopedics and Traumatology Service of Muğla Sıtkı Koçman University Training and Research Hospital and who have undergone proximal femur fracture surgery and meet the study criteria. It is aimed to investigate the mid-term efficacy of relaxation exercises and classical massage of the sole of the foot applied in addition to the conventional physiotherapy program in the postoperative in-hospital period in patients with proximal femur fracture.

NCT ID: NCT05947292 Recruiting - Femur Fracture Clinical Trials

Study Comparing Ultrasound-guided FICNB Block to Systemic Analgesia in Treatment of Pediatric Femur Fracture

PLEXUS
Start date: June 1, 2022
Phase:
Study type: Observational

The goal of this prospective observational study is to compare pain control strategies in children with femur fractures. Researchers will compare ultrasound-guided fascia iliaca compartment nerve block to IV pain control alone. The main questions it aims to answer are: - Are ultrasound-guided fascia iliaca compartment nerve blocks as effective as IV pain control in controlling pain? - Do patients who receive an ultrasound-guided fascia iliaca compartment nerve block require less opioid pain medication than those that don't? Participants will be asked to provide pain scores during their Emergency Department stay. Participants parents will be asked to complete a brief survey at the time their child is leaving the Emergency Department.

NCT ID: NCT05920642 Recruiting - Clinical trials for Proximal Femur Fracture

Postoperative Pain Relieve for Patients Undergoing Surgical Treatment of Femoral Fracture

Start date: September 4, 2023
Phase: Phase 4
Study type: Interventional

The aim of the study is to investigate postoperative pain relief for patients undergoing surgical treatment of proximal femoral fracture using intrathecal administration of morphine.

NCT ID: NCT05882201 Recruiting - Clinical trials for Regional Anesthesia Morbidity

Comparison of Femoral Nerve Block Versus Fascia Iliaca Compartment Block for Pain Control in Traumatic Femur Fracture Repair in Pediatric Population

Start date: June 1, 2023
Phase: N/A
Study type: Interventional

Pediatric orthopedic surgical procedures require a multimodal approach for anesthetic management that maximizes both patient comfort and safety. (1) A multimodal strategy for perioperative pain management is often required for children undergoing orthopedic surgery including pharmacological methods, and regional anesthesia (R.A). (1,2) Recent guidelines published jointly by the European Society of Regional Anesthesia (ESRA) and the American Society of Regional Anesthesia (ASRA) recommend that regional blocks can and should preferably be performed under general anesthesia or deep sedation in children of all ages. (3,4) Many studies investigated the safety of regional pediatric nerve blocks These studies showed pediatric complication rates consistent with adult data. These complications include nerve injury, intravascular injection and local anesthetics systemic toxicity (LAST), and acute compartmental syndrome. these complications have been minimized by ultrasound-guided nerve block in pediatrics. (5) The annual incidence of pediatric femoral fractures is estimated to be 19 per 100,000. Femoral fractures are usually associated with other injuries such as intracranial hemorrhages, lung contusions, hemothorax or pneumothorax, and other organ injuries which make regional anesthesia (R.A) is preferable as a sole technique or combined with general anesthesia to decrease the overall dosage of anesthetics and opioids. (6) The most tangible advantage of RA is profound and prolonged pain relief. Alternatively, pain relief can be given by opioids which are known to cause nausea, vomiting, respiratory depression, decrease in gut motility and increase apneic spells in the population vulnerable to the same. Nonsteroidal anti- inflammatory drugs can affect the immature renal system adversely. RA offers pain relief without changing the physiological milieu. (7) Fascia iliaca Compartment Block (FICB) has been widely used for postoperative analgesia in patients undergoing hip, femoral bone, and knee surgical procedures. FICB was first introduced by Dalens et al in 1989. This regional plane block technique was used to block the femoral nerve and the lateral femoral cutaneous nerve of the thigh and the obturator nerve with a high level of safety and success, well-suited for the anterolateral surgeries of the thigh. (8,9) Femoral nerve block (FNB) has been widely used for postoperative analgesia in patients undergoing hip, and femoral bone surgical procedures, it provides anesthesia and analgesia for the lateral aspect of the thigh and the femur bone. (10,11) FICB has a wider range of anesthesia and analgesia in lower limbs compared to FNB. but the use of dilute injectate in FICB may minimize sensory and motor block than FNB. (1,16) This study will be conducted to evaluate the effects of FICB vs FNB in pain control in pediatrics undergoing femoral fracture repair surgery.