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Femoral Fractures clinical trials

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NCT ID: NCT05840458 Recruiting - Femoral Fracture Clinical Trials

Pericapsular Nerve Block in Proximal Femoral Fractures

Start date: April 1, 2023
Phase:
Study type: Observational

Proximal femoral fractures commonly occur above 50 years and regional anesthesia could be a complement in the perioperative treatment of the patients. The use of pericapsular nerve group block (PENG Block) has been proposed to reduce pain. However, no studies have explored the efficient of the systemic analgesia associated with PENG Block in functional limitation in the preoperative period. In this sense, the main goal of this study is to evaluate the effectiveness of systemic analgesia associated with PENG Block in patients with proximal femoral fractures in the period preceding the surgical procedure.

NCT ID: NCT05805774 Recruiting - Clinical trials for Distal Femur Fracture

pDIFFIR: Geriatric Periprosthetic DIstal Femur: FIxation Versus Replacement

pDIFFIR
Start date: February 1, 2024
Phase: N/A
Study type: Interventional

Periprosthetic distal femur fractures are a significant source of morbidity and mortality for elderly patients. One treatment option involved a surgical fixation with plates or nails, screws and cables/wires along the side of your fractured bone. The second method consists in replacing your knee joint with an artificial knee prosthesis (artificial knee joint). The primary objective is to determine if acute distal femur replacement improves knee pain and functional outcomes compared to surgical fixation. Secondary outcomes are mortality, reoperation, complications, post-operative pain and quality of life. A health economic analysis will be conducted to assess the cost-effectiveness of both treatments. A total of 148 patients (74/group) will be enrolled in the study.

NCT ID: NCT05792189 Recruiting - Clinical trials for Distal Femur Fracture

Distal Femur Fx: ORIF(Open Reduction and Internal Fixation) vs DFR (Distal Femur Replacement Total Knee Arthroplasty)

Start date: April 12, 2023
Phase: N/A
Study type: Interventional

Supracondylar femur periprosthetic fractures about a total knee arthroplasty (TKA) are a catastrophic and challenging complication of TKA and unfortunately are increasing in incidence. Fixation of these fractures can be challenging due to altered anatomy for the TKA and the presence of the metallic femoral component and have a relatively high complication rate. As a result, some surgeons elect to treat these fractures with a distal femur replacement total knee arthroplasty (DFR). The purpose of this study is to prospectively evaluate periprosthetic femur fractures treated with ORIF or DFR and compare various outcomes measures (Get up and go times, KOOS Jr score)

NCT ID: NCT05705726 Recruiting - Pain Clinical Trials

Fascia Iliaca Block Versus Intravenous Dexmedetomidine and Ketamine for Positioning Fracture Femur

Start date: February 11, 2023
Phase: N/A
Study type: Interventional

Proximal femur fractures are one of the commonest fractures especially in the elderly population. Early surgical fixation is the best analgesic for associated pain. Spinal anesthesia has been favored by many anesthesiologists due to the simplicity of the technique, the better analgesic profile, and the lower incidence of complications like delirium and thromboembolic events. However, severe pain, encountered during positioning for spinal anesthesia, can complicate the technique and worsen the patient experience. the study aim to compare the analgesic effect of intravenous dexmedetomidine and fascia iliaca block preoperatively to assist positioning patients for performance of spinal anesthesia.

NCT ID: NCT05680987 Recruiting - Femoral Fracture Clinical Trials

Retrograde Femoral Nail-Advanced Outcomes for Fixation of Distal Femur and Femoral Shaft Fractures

Start date: June 23, 2021
Phase: N/A
Study type: Interventional

This project consists of a prospective and retrospective case series design. Study candidates will include all patients 18 years or older, who were evaluated at UCSD and found to have a distal femur or femoral shaft fracture requiring surgical fixation. Patients who consent to study participation will recieve the RFN-advanced Retrograde Femoral Nailing System implant for fracture fixation. Data on functional status, healing rates, complication rates, and pain levels will be collected for each participant. After 3 years of data collection, investigators will analyze this data to provide further insight on the utility of this new design of retrograde femoral nails. Given the relatively high rate of complications, such as malalignment, with current femoral nail designs, it is imperative to evaluate novel systems to appropriately manage distal femur or femoral shaft fractures.

NCT ID: NCT05669040 Recruiting - Fracture of Femur Clinical Trials

mHealth to Improve the Experience, Adherence to Drug Treatment and Positive Mental Health

Start date: November 21, 2022
Phase: N/A
Study type: Interventional

The present study aims to evaluate the effectiveness of a pharmacological nursing educational intervention (EFE) with "Myplan Aplication" about the patient's experience, adherence to pharmacological treatment, and positive mental health of patients with femur fracture.

NCT ID: NCT05668182 Recruiting - Femoral Fracture Clinical Trials

A Case Series: TRUMATCH Graft Cage for Segmental Long Bone Defects

Start date: June 29, 2021
Phase:
Study type: Observational

This project consists of a prospective case design. Study candidates will include all patients ages 18 and over who were evaluated at UCSD and found to have a critical-sized humerus, femur, or tibia segmental defect that would be fixed through surgery. Patients who consent to study participation will receive the TRUMATCH Graft Cage for their long bone segmental defect repair. Data on healing rates, complication rates, re-operation rates, time to return to normal activity, and pain levels will be collected for each participation. After 3 years of data collection, we will analyze this data to provide further insight on the utility of the TRUMATCH Graft Cage. Given the significant difficulty with repairing segmental long bone defects, it is imperative to evaluate novel systems to appropriately manage these injuries.

NCT ID: NCT05620394 Recruiting - Clinical trials for Femur Fracture, Childhood

Study of the Geometry of the Immature Human Femur Before the Age of 3 Years From Data Measured on CT Scan

GFI
Start date: October 7, 2020
Phase:
Study type: Observational

Childhood fractures are the second most common presentation of abuse. The target population for screening for these injuries is children under the age of three who are unable to express themselves about the circumstances of the trauma, hence the need to develop a validated model to predict the outcome of trauma as well as the origin of a fracture. Few morphological data are available in the literature for the femur concerning the period of rapid growth between 0 and 3 years of age.

NCT ID: NCT05559736 Recruiting - Clinical trials for Femoral Neck Fractures

Artemis Proximal Femoral Nail for Internal Fixation of Intertrochanteric Femur Fractures

Start date: May 24, 2023
Phase: N/A
Study type: Interventional

In February 2021, Altior Trauma Innovations™ announced that it had received 501(k) FDA approval for the Artemis Proximal Femoral Nail (PFN) System for internal fixation of intertrochanteric femur fractures. The objective of this pilot study is to evaluate safety, efficacy and feasibility of the Artemis PFN implant for operative fixation of intertrochanteric femoral fractures, compared to matched historical control patients who received other implants.

NCT ID: NCT05523635 Recruiting - Femoral Fracture Clinical Trials

Post Market Clinical Evaluation of Gamma 4

PEGASUS
Start date: March 6, 2023
Phase:
Study type: Observational

This is a prospective, multi-center, non-randomized, post-market clinical investigation of the Gamma 4 System. Neither subjects nor investigators are blinded to treatment. It is anticipated that a total of 100 subjects will be enrolled at five sites. Total duration of enrollment, 12 month follow-up and analysis is expected to take approximately 30 months. The clinical investigation has been designed to follow the surgeon's standard of care for subjects treated with a cephalomedullary nail for femoral fractures or and deformities, in addition to a 12 month follow-up visit. The primary endpoint of this clinical investigation is demonstration of bone consolidation by 12 months.