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Femoral Fractures clinical trials

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NCT ID: NCT06430944 Completed - Femur Fracture Clinical Trials

Comparative Study Between Single and Double Limb Hip Spica Cast in Fracture Femur in Young Children

Start date: May 1, 2022
Phase: N/A
Study type: Interventional

We performed a randomized control trial including 84 children aged two to six years who presented with femoral fractures. They were randomized into two groups; the first was managed by single limb cast fixation (42 patients), and the second was managed by double limb cast fixation (42 patients). The primary outcomes were postprocedural functional outcomes and parents' satisfaction, while the secondary outcomes were the rates of complications.

NCT ID: NCT06382584 Completed - Surgery Clinical Trials

Impact of Treatment With Oral Anticoagulants of Patients With Fractures of the Upper End of the Femur

ANTI_XA
Start date: January 1, 2022
Phase:
Study type: Observational

In 2023, oral anticoagulant treatments (anti Xa: apixaban , rivaroxaban, etc.) are tending to replace anti vitamin K treatments in many medical indications. Their prescription is increasing rapidly in the elderly. In this context, the Nimes University Hospital receives a large number of elderly patients who have suffered a fracture of the end of the femur requiring surgery and who are taking anti Xa drugs.To avoid massive intra- and post-operative haemorrhage, surgical management is postponed because of the need to suspend the treatment, allowing a return to near-normal biological haemostasis within a few days. No consensus has been reached on the withdrawal period required to authorise surgery, as the elimination kinetics of the drug are altered in this context (elderly patients, dehydration, hypovolaemia, impaired renal function). A plasma assay (threshold of <30 to 60 ng/mL) has been proposed without any real justification. This waiting period exposes the elderly to excess mortality. Reversing these treatments by adding coagulation factors would be an attractive alternative, as it would allow surgery to be performed earlier, but this would expose patients to an increased thrombotic risk. Before considering a prospective randomised study (early vs delayed surgery on AOD), we wish to retrospectively analyse data on patients admitted to the Nimes University Hospital on anti Xa and operated on for fracture of the upper end of the femur between 1 January 2022 and 1 June 2023

NCT ID: NCT06360835 Completed - Clinical trials for Proximal Femur Fractures

Our Experience in the Management of Therapeutic Failures of Fractures of the Proximal End of the Femur (About 35 Cases)

Start date: January 1, 2015
Phase:
Study type: Observational

Osteosyntheses employed in treating fractures at the upper end of the femur play a critical role in facilitating a swift recovery by minimizing immobilization periods and enabling early rehabilitation of the affected joints, thereby promoting a speedy return to normal walking function. Osteosynthesis alters the mechanical dynamics of the bone segment, which undergoes continual changes during the consolidation and mobilization phases of recovery. Throughout these stages, a range of mechanical complications may arise, posing challenges despite the successful prevention of infections. Non-infectious complications associated with the presence of osteosynthesis materials, especially in weight-bearing areas like the lower limb, remain a concern. In light of these considerations, surgeons must exercise meticulous care in selecting synthetic materials to mitigate the risk of osteosynthesis failures. In cases where internal fixation fails, the standard recourse often involves converting to total hip arthroplasty (THA). However, it is essential to note that THA subsequent to complications arising from proximal femur osteosynthesis presents a higher incidence of both intraoperative and postoperative complications compared to the implantation of primary total hip prostheses. Thus, while osteosynthesis remains a valuable intervention for femur fractures, careful attention to material selection and postoperative management is crucial in optimizing patient outcomes and minimizing complications.

NCT ID: NCT06220422 Completed - Femur Fracture Clinical Trials

Assessment of a Procedure for Managing Oral Anticoagulants (NACO) in the Management of Fractures

STOP-NACO
Start date: February 26, 2024
Phase:
Study type: Observational

The purpose of this study is to demonstrate that by allowing patients with an anticoagulant level less than 100 ng/ml to have their fracture managed surgically, will reduce the delay in surgery and therefore the complications associated. It will also demonstrate that there are no more complications with this new management than from remaining with a bleeding fracture.

NCT ID: NCT06155903 Completed - Spinal Anesthesia Clinical Trials

Peripheral Nerve Block vs Spinal Anesthesia in Patients With Femur Fracture

Start date: July 1, 2023
Phase: N/A
Study type: Interventional

Femur Fractures (PF) are nowadays one of the main social and health problems in industrialized countries. PF are defined as crack or break of the proximal femur and they represent an important cause of morbidity and mortality in elderly population. The main prospective and retrospective studies do not show the superiority of subarachnoid anesthesia over general anesthesia in terms of 30-day mortality and post-operative complications, however they always recommend the execution of PeripheralNerve Blocks (PNB). Loco-regional anesthesia plays a fundamental role in the treatment of peri-operative pain assuring better hemodynamic stability and has already fully entered national and international pain management protocols, because it allows faster recovery times with a reduction in the use of intravenous analgesic drugs in particular opioids and consequently a faster discharge and a reduction in peri-operative complications and the costs of assistance. The aim of our study will be to propose an anesthetic approach based on PNB that could be particularly suitable for frail patients especially when Neuroaxial Anesthesia (NA) is not feasible due to difficulty to position the patient or to the withdrawal time of anticoagulant or antiplatelet therapies.

NCT ID: NCT06026150 Completed - Femoral Fractures Clinical Trials

Anatomical Variations of Femoral Nerve Location in Relation to Femoral Artery

Start date: April 10, 2016
Phase:
Study type: Observational

The goal of this observational study is to learn about the relative position of femoral nerve in relation to the femoral artery in patients scheduled for femoral fractures using ultrasound scanning. The classical description of femoral nerve is that it lies immediately near to artery, but it is not always true. The nerve lies at a varying distance from the artery. The main question it aims to answer are: • Is the age sex and Body Mass Index affect the relationship between femoral artery and nerve?

NCT ID: NCT05817916 Completed - Femur Fracture Clinical Trials

Comparison of Erector Spina Plane Block and Lumbar Plexus Block in Femoral Fracture Surgery

Start date: April 15, 2023
Phase: N/A
Study type: Interventional

The aim is to clinical trials compare the lumbar plexus block method with the erector spinae plan block method in terms of analgesic efficacy and possible complications. İn patients for femur fracture surgery. The main questions it aims to answer are: 1. is erector spinae plane block as effective as lumbar plexus block for postoperative analgesia in femur fractures? 2. Is erector spinae plane block effective for reducing opioid consumption compared to lumbar plexus block?

NCT ID: NCT05804604 Completed - Bone Loss Clinical Trials

Bone Intake Proteins and Muscle Mass Deficiency in Proximal Femur Fractures

Start date: May 7, 2022
Phase:
Study type: Observational

The aim of this clinical trial is to compare serum concentration of bone intake proteins [ sex hormone-binding globulin (SHBG), cross linked C-telopeptide of type I collagen (CTX-I)] and muscle atrophy marker [creatine kinase (CK-MB)] between patients after the fracture of proximal femur and their age corresponding counterpart without the fracture. The main question it aims to answer is: • Is the higher concentration of bone intake proteins and muscle atrophy marker a predictive factor of proximal femur fracture? The part of participants (Group 1) will be hospitalized at the Department of Orthopaedics and Rehabilitation and will undergo a surgical treatment (open reduction of the fracture). The rest (Group 2) will be admitted to the Department of Internal Medicine. Participants of both Groups will have the blood sample test taken, to evaluate and compare the serum concentration of SHBG, CTX-I and CK-MB proteins.

NCT ID: NCT05737459 Completed - Clinical trials for Cognitive Impairment

Sedation and Postoperative Cognitive Functions

Start date: May 1, 2022
Phase:
Study type: Observational [Patient Registry]

Patients over the age of 65 who underwent elective surgery for a hip fracture and were sedated during spinal anesthesia were included in the study. Patients who were given ketamine and dexmedetomidine for sedation were included in the study. The Mini Mental Status Tests of the patients measured on the first and third days of the operation in the preoperative period were determined from the hospital records and recorded.

NCT ID: NCT05677061 Completed - Clinical trials for Intertrochanteric Fractures

Clinical Evaluation on HA Coated Dynamic Hip Screws for Trochanteric Femoral Fractures

Start date: April 2008
Phase: N/A
Study type: Interventional

Evaluated whether HA coated dynamic hip screws can improve fixation of the screw in trochanteric femoral fractures