Female Infertility of Tubal Origin Clinical Trial
Official title:
The Effect of Intracervical Lidocaine Versus Intramuscular Diclofenac for Pain Relief During Hysterosalpingography Among Infertile Women In A Tertiary Hospital In Kano: A Randomized Controlled Trial
This study compares the effect of intracervical block with 1% lidocaine and intramuscular diclofenac 75mg in decreasing pain perception during hysterosalpingography. Half of participants will receive intracervical block with 1% lidocaine, while the other half will receive intramuscular diclofenac 75mg.
Hysterosalpingography (HSG) is a radiographic test to evaluate the contour of the uterine
cavity and patency of the fallopian tubes after injection of a radio-opaque dye through the
cervix. It is typically performed in the evaluation of infertility or to diagnose uterine
anomalies. It is the most common method of tubal evaluation in the developing countries
because it is cheap, readily available and requires less expertise. Unfortunately, HSG can
cause discomfort or pain for the patient during or after the procedure, and this evokes
anxiety and fear for many patients. Up to 72 % of women complain of significant discomfort
with this test.
Lidocaine is a local anaesthetic which exerts its effect by altering neuronal depolarization
by blocking the sodium channels in the cell membrane, thereby preventing transmission of the
sensation of pain to the higher neurons. Lidocaine is commonly used for infiltration and for
peripheral nerve blocks if an intermediate duration is required.
Diclofenac is a Non-steroidal anti inflammatory drug that reduce nociception which is
related to inflammation and inflammatory mediators whether from trauma
;
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver), Primary Purpose: Diagnostic
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT04071574 -
Comparative Study on the Efficacy of Ovarian Stimulation Protocols on the Success Rate of ICSI in Female Infertility
|
Phase 1/Phase 2 |