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Exercise-induced Muscle Damage clinical trials

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NCT ID: NCT05346211 Not yet recruiting - Clinical trials for Exercise Induced Muscle Damage

The Effect of Curcumin Supplementation on Recovery From Exercise-induced Muscle Damage

Start date: May 1, 2022
Phase: N/A
Study type: Interventional

Recent evidence suggests that curcumin supplementation may reduce muscle inflammation, oxidative markers, and muscle damage. The most favourable dosage to elicit these ergogenic effects are yet to be established; both 750mg & 1500mg has been shown to be effective. Curcumin supplementation has been ingested in numerous different ways however, no previous research to date has used curcumin in a hydrolysed (drinkable) format. The aim of this study is to investigate whether hydrolysed curcumin can reduce indices of muscle damage and improve recovery, whilst also examining a potential dose-response effect.

NCT ID: NCT04458662 Completed - Inflammation Clinical Trials

Iron and Muscular Damage: FEmale Metabolism and Menstrual Cycle During Exercise

IronFEMME
Start date: January 1, 2017
Phase:
Study type: Observational [Patient Registry]

This project is an observational controlled randomized counterbalance study. One hundred and three physically active and healthy women were selected to participate in the IronFEMME Study, of which 57 were eumenorrheic, 30 were oral contraceptive users (OCP) and 16 were postmenopausal women. The project consisted on two sections carrying out at the same time: Iron metabolism (Study I) and Muscle damage (Study II). For the study I, the exercise protocol consisted on an interval running test (8 bouts of 3 min at 85% of the maximal aerobic speed), whereas the study II protocol was based on an eccentric-based resistance exercise protocol (10 sets of 10 repetitions of plate-loaded barbell parallel back squats at 60% of their 1RM with 2 min of rest between sets). In both studies, eumenorrheic participants were evaluated at three specific moments of the menstrual cycle: Early-follicular phase, late-follicular phase and mid-luteal phase; OCP performed the trial at two moments: Withdrawal phase and active pill phase. Lastly, postmenopausal women were tested only once, since their hormonal status does not fluctuate. The three-step method was used to verify the menstrual cycle phase: calendar counting, blood analyses confirmation and urine-based ovulation kits. Blood samples were obtained to measure sexual hormones (e.g., 17β-Estradiol, Progesterone), iron metabolism parameters (e.g., Hepcidin, Iron, Ferritin, Transferrin) and muscle damage related markers (e.g., Creatine Kinase, Myoglobin, Lactate Dehydrogenase).

NCT ID: NCT04273789 Completed - Clinical trials for Exercise Induced Muscle Damage

Effect of Far Infrared Reflecting Sleepwear on Recovery and Sleep

Start date: February 17, 2020
Phase: N/A
Study type: Interventional

Far infrared light (FIR, 5.6-1000 µm) penetrates our skin and reaches the underlying tissue up to 4 cm and promotes widening of the blood vessels (vasodilation). This results in increased blood flow in the tissue under the skin, without heating up the skin itself. Increased blood flow allows more oxygen to reach the muscles and more metabolic waste products to be transported away from the muscles. Studies assessing clothing containing an FDA approved ceramic particles covered yarn that reflect FIR light showed delayed onset muscle pain decreased and a reduction in inflammatory markers in professional athletes. The aim of this study is to investigate the effect of far infrared reflecting sleepwear on night-time recovery and Sleep in a broader population, namely physically active adults (non-professional).

NCT ID: NCT04183816 Completed - Clinical trials for Exercise-induced Muscle Damage

Effect of Total Cold Water Immersion Vs Ice Massage Modalities

Start date: November 1, 2018
Phase: N/A
Study type: Interventional

Evidence regarding the effect of the therapeutic modalities on muscle recovery after exercise-induced muscle damage (EIMD) was lacking. Therefore, this study played a role in bridging this gap, where total cold-water immersion (TCWI) values return to baseline 72 h after the muscle damage protocol, regarding creatine kinase (CK) levels, power and strength, and delayed onset of muscle soreness (DOMS).

NCT ID: NCT03284450 Completed - Clinical trials for Exercise Induced Muscle Damage

Exercise Induced Muscle Damage Post Dance and Sprint Specific Exercise in Females

Start date: April 2014
Phase: N/A
Study type: Interventional

There is a paucity of studies investigating exercise-induced muscle damage (EIMD) in females and only one in response to dance-type exercise. This study aimed to firstly elucidate the physiological profile of EIMD following a dance-specific protocol, and second to compare the magnitude of damage to that experienced following a sport-specific protocol in physically active females.

NCT ID: NCT03203785 Completed - Fatigue Clinical Trials

Effect of Carbohydrate Consumption on Fatigue and Muscle Damage in Jiu-Jitsu Athletes

Start date: June 26, 2017
Phase: N/A
Study type: Interventional

The study is a randomized, double-blinded, placebo-controlled trial that will include the participation of 14 Jiu-Jitsu athletes between 18 and 33 years. The aim of the study is to evaluate the effects of carbohydrate consumption on fatigue and exercise-induced muscle damage in Jiu-Jitsu athletes.

NCT ID: NCT03160937 Completed - Movement Disorders Clinical Trials

Neurodynamic Mobilization and Foam Rolling

Start date: January 10, 2017
Phase: N/A
Study type: Interventional

The purpose of this study was to assess the acute effects of a single NM treatment session on DOMS and to compare them with those of one foam roller (FR) session. Following the damaging plyometric exercise bout, the participants were randomly assigned in a counter-balanced fashion to either a FR or NM treatment group; treatments were administered 48-h post-exercise. The dependent variables were recorded before the exercise, 48-h post-exercise before treatment, and immediately post-treatment.

NCT ID: NCT01907841 Completed - Clinical trials for Exercise-induced Muscle Damage

The Effect of Ischemic Pre-Conditioning on the Rate of Recovery Following Exercise-Induced Muscle Damage

Start date: July 2013
Phase: N/A
Study type: Interventional

Strenuous exercise or exercise involving eccentric muscle contractions can lead to muscle damage and changes in muscle function; this is known as exercise-induced muscle damage (EIMD). It is known that brief, repeated periods of ischemia followed by reperfusion, known as Ischemic Preconditioning (IPC) cause a delay in cell injury in cardiac muscle as well as in various other organs. Therefore the purpose of this study is to: 1. Quantify the use of IPC in recovery following EIMD. 2. Identify any effect of IPC during recovery on muscle function

NCT ID: NCT01845558 Completed - Muscle Soreness Clinical Trials

Effects of Wobenzym® Plus in Healthy, Sportive People After Eccentric Exercise

2012-005003-40
Start date: February 2013
Phase: Phase 4
Study type: Interventional

The aim of the current study is to investigate the therapeutic effect and especially the mode of action of Wobenzym® plus, an anti-inflammatory drug containing proteolytic enzymes, on exercise induced muscle damage (eiMD) and recovery time in male amateur sportsmen with medium proficiency level compared to placebo.

NCT ID: NCT01529281 Completed - Clinical trials for Exercise-induced Muscle Damage

Exercise-induced Muscle Damage is Reduced in Resistance Trained Athletes by Branch Chain Amino Acids

Start date: June 2011
Phase: N/A
Study type: Interventional

It is well documented that exercise-induced muscle damage (EIMD) decreases muscle function and causes severe soreness and discomfort. Branched-chain amino acid (BCAA) supplementation has been shown to increase protein synthesis and decrease muscle protein breakdown, however, the effects of BCAAs on recovery from EIMD are unknown. Thus, the aim of this study was to examine the effects of a BCAA supplement on markers of muscle damage.