Clinical Trials Logo

Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT05987436
Other study ID # HKara2
Secondary ID
Status Completed
Phase
First received
Last updated
Start date November 1, 2017
Est. completion date December 1, 2019

Study information

Verified date August 2023
Source TC Erciyes University
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The goal of this observational study is to evaluate the effects of a supervised aerobic exercise training program on weight loss, functional capacity, quality of life (QoL), and depression levels in patients with essential hypertension.


Description:

Patients who chose the treatment type according to personal preferences were divided into two groups: Group 1(n:91) exercised for six weeks, five sessions per week under the supervision of a medical doctor in the aerobic exercise laboratory, and group 2(n:47) was advised to maintain dietary habits and physical activity levels. Body weight, serum lipid levels, functional capacity, QoL, and depression level of all the participants were evaluated at baseline and 6 weeks later.


Recruitment information / eligibility

Status Completed
Enrollment 138
Est. completion date December 1, 2019
Est. primary completion date April 1, 2019
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years to 75 Years
Eligibility Inclusion Criteria: - Over 18 years of age, - Absence of concomitant other metabolic and cardiovascular diseases. Exclusion Criteria: - Having suffered an event of ischaemic heart disease (<6 months), - Secondary hypertension, - Hypertrophic obstructive cardiomyopathy, - Congestive heart failure, - Uncontrolled cardiac arrhythmia, - Thyroid dysfunction, - Diabetes mellitus, - Symptomatic peripheral arterial occlusive disease, - Aortic insufficiency or stenosis, - Pulmonary or heart disease with dyspnoea at small or moderate effort, - An outbreak of orthopedic problems on hip, knee or ankles, such as arthroplasty, contracture or severe osteoarthritis, - Using of antidepressant or anxiolytic drugs, - Pregnancy, - Cognitive disfunction.

Study Design


Related Conditions & MeSH terms


Intervention

Other:
Supervised Aerobic Exercise
Group 1 exercised for six weeks, five sessions per week under the supervision of a medical doctor in the aerobic exercise laboratory.

Locations

Country Name City State
Turkey Selcuk University Faculty of Medicine Konya

Sponsors (1)

Lead Sponsor Collaborator
TC Erciyes University

Country where clinical trial is conducted

Turkey, 

Outcome

Type Measure Description Time frame Safety issue
Primary Body weight kilograms was measured at the pre-treatment period and the post-treatment 6th week for all the participants by the same physician.
Primary Blood samples Serum total cholesterol, high-density lipoprotein (HDL) cholesterol, low-density lipoprotein (LDL) cholesterol, very-low-density lipoprotein (VLDL) cholesterol, and triglycerides Twelve-hour fasting blood samples were collected between 6.00 am, and 10.00 am at baseline and week 6.
Primary The functional capacity The 6MWT test and the estimated metabolic equivalents or METs were used performed to evaluate functional capacity. 6MWT was assessed in face-to-face interviews before and immediately after the treatment was completed.
Primary Quality of Life Quality of life was assessed with Short Form-36 (SF-36). SF36 was assessed in face-to-face interviews before and immediately after the treatment was completed.
Primary Depression level Depression level was assessed Beck Depression Inventory (BDI). BDI was assessed in face-to-face interviews before and immediately after the treatment was completed.
See also
  Status Clinical Trial Phase
Recruiting NCT03708601 - Prognostic Risk of Patients With Essential Hypertension for Cardiovascular Events (PROSPECT)
Not yet recruiting NCT05503953 - Phase III Study to Evaluate the Efficacy and Safety of AGSAVI in Patients With Essential Hypertension Inadequately Controlled With AGLS Phase 3
Recruiting NCT05526703 - Clinical Trial to Evaluate the Efficacy and Safety of D064 and D701 Combination Therapy Phase 3
Completed NCT06395194 - Effects of Valsartan vs Amlodipine and Low BP on Kidney Outcomes in Essential Hypertension Phase 3
Not yet recruiting NCT06418074 - Effects of Exogenous Ketosis on Renal Function, Renal Perfusion, and Sodium Excretory Capacity N/A
Completed NCT02890173 - Study of CS-3150 in Patients With Essential Hypertension Phase 3
Withdrawn NCT02096939 - Microvascular Function in Primary Aldosteronism N/A
Completed NCT02944734 - Comparison of Efficacy and Safety of Combination Therapy and Monotherapy of Candesartan and Amlodipine for Dose-Finding in Patients With Essential Hypertension Phase 2
Recruiting NCT01956786 - Efficacy of Amlodipine-Folic Acid Tablets on Reduction of Blood Pressure and Plasma Homocysteine Phase 2/Phase 3
Completed NCT02553512 - Helius in Hypertension-I: The UK Hypertension Registry N/A
Completed NCT01198249 - Pharmacokinetic Drug Interactions Between Single and Concomitant Administrations of Amlodipine, Losartan, and Hydrochlorothiazide in Subjects With (Pre)Hypertension Phase 1
Completed NCT01001572 - Efficacy and Safety of Valsartan/Amlodipine in Patients With Mild to Moderate Essential Hypertension Phase 3
Recruiting NCT00380289 - Early Metabolic Changes With Thiazide or Beta Blocker Therapy for Essential Hypertension N/A
Completed NCT00139698 - Olmesartan Alone or in Combination With Hydrochlorothiazide in Subjects With Mild to Moderate Essential Hypertension Phase 3
Completed NCT00288184 - Uric Acid in Essential Hypertension in Children Phase 2
Completed NCT01289886 - Fimasartan (BR-A-657) Single Oral Dose in Healthy Subjects Phase 1
Not yet recruiting NCT06041529 - Study to Evaluate the Efficacy and Safety of TEL/AML/CTD in Elderly Patients With Essential Hypertension Phase 4
Completed NCT04470830 - A Study for PMS of AZL-M/CLD FDC in the Treatment of Participants With Essential HTN in South Korea
Completed NCT00758524 - A Study to Evaluate Efficacy and Safety of LCI699 in Participants With Essential Hypertension Phase 2
Recruiting NCT05109013 - Juvenile Essential Arterial Hypertension and Vascular Function