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Esophageal Cancer clinical trials

View clinical trials related to Esophageal Cancer.

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NCT ID: NCT05894369 Recruiting - Esophageal Cancer Clinical Trials

Influence Mechanism of Tumor Microenvironment Changes on Neoadjuvant Therapy for Esophageal Squamous Cell Carcinoma

Start date: May 4, 2023
Phase:
Study type: Observational [Patient Registry]

To evaluate the predictive value and mechanism of inflammatory factors in peripheral blood on the prognosis of patients, and to explore the influencing factors of inflammation and tumor microenvironment on the efficacy of neoadjuvant chemotherapy combined with immunotherapy for esophageal cancer. To explore the predictors of neoadjuvant therapy in patients with esophageal squamous cell carcinoma.

NCT ID: NCT05891171 Recruiting - Ovarian Cancer Clinical Trials

Study of AB598 Monotherapy and Combination Therapy in Participants With Advanced Cancers

ARC-25
Start date: October 13, 2023
Phase: Phase 1
Study type: Interventional

The primary purpose of this study is to assess the safety and tolerability of AB598 when taken alone, and in combination with zimberelimab and standard chemotherapy in participants with advanced malignancies.

NCT ID: NCT05866510 Recruiting - Esophageal Cancer Clinical Trials

Utidelone and Anlotinib in Advanced Recurrent Metastatic Esophageal Cancer

Start date: May 15, 2023
Phase: Phase 2
Study type: Interventional

The goal of this clinical trial is to evaluate the safety, tolerance and efficacy of Utidelone combined with Anlotinib in patients with Advanced or Recurrent Esophageal Carcinoma who failed Standard first line therapy.

NCT ID: NCT05865743 Not yet recruiting - Esophageal Cancer Clinical Trials

Perioperative SDD to Prevent Infectious Complications After Esophagectomy

PERSuaDER
Start date: June 2024
Phase: Phase 3
Study type: Interventional

The primary aim of the PERSuaDER-trial is to evaluate the effect of SDD on infectious complications after esophagectomy, focussed on the prevention of pneumonia

NCT ID: NCT05864144 Recruiting - Breast Cancer Clinical Trials

A Study of SNS-101 (Anti VISTA) Monotherapy and in Combination With Cemiplimab in Patients With Advanced Solid Tumors

Start date: May 31, 2023
Phase: Phase 1/Phase 2
Study type: Interventional

Phase 1/2 study to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, and efficacy of SNS-101, a novel anti VISTA IgG1 monoclonal antibody as monotherapy or in combination with cemiplimab in patients with advanced solid tumors.

NCT ID: NCT05858736 Recruiting - Colorectal Cancer Clinical Trials

Safety, PK and Efficacy of AI-061 in Advanced Solid Tumors

PRESERVE-009
Start date: July 11, 2023
Phase: Phase 1
Study type: Interventional

AI-061 is a co-formulation drug product (DP) consisting of 1:1 ratio mix of AI-025, an anti-PD-1 antibody, and ONC-392, an anti-CTLA-4 antibody. This is a dose escalation study to identify the maximum toxicity dose (MTD) or the recommended phase 2 dose (RP2D).

NCT ID: NCT05855291 Completed - Esophageal Cancer Clinical Trials

PET/MRI in Predicting the Outcome of Neoadjuvant Chemoradiotherapy With Esophagectomy in Esophageal Cancer Patients

Start date: January 22, 2018
Phase: N/A
Study type: Interventional

Integrated PET/MRI has the advantage to assess the metabolism, diffusion, and perfusion parameters of the tumor simultaneously. Recently, PET/MRI has been investigated in several cancers with promising results. In this study, we prospectively investigate the role of multiparametric PET/MRI in evaluating the outcome of patients with esophageal cancer treated by neoadjuvant chemoradiotherapy and surgery.

NCT ID: NCT05855278 Completed - Esophageal Cancer Clinical Trials

The Role of PET/MRI in Predicting the Outcome of Definitive Chemoradiotherapy for Esophageal Cancer Patients

Start date: August 13, 2019
Phase: N/A
Study type: Interventional

PET/MRI has the advantage to assess the metabolism, diffusion, and perfusion parameters of the tumor simultaneously and has been investigated in some cancers with promising results. In this study, we prospectively investigate the role of PET/MRI in evaluating the outcome of patients with esophageal cancer treated by definitive chemoradiotherapy.

NCT ID: NCT05846971 Active, not recruiting - Esophageal Cancer Clinical Trials

Clinical Utility of Methylation-based Prognostic Assay for Barrett's Esophagus

Start date: January 26, 2021
Phase: N/A
Study type: Interventional

Capsulomics has developed a prognostic assay for patients with diagnosed Barrett's esophagus (BE). This study will measure how gastroenterologists make surveillance and treatment management decisions when presented with different clinical and prognostic assay information.

NCT ID: NCT05831150 Not yet recruiting - Esophageal Cancer Clinical Trials

Discovering Patterns in Experiences of Patients in Esophageal Cancer Clinical Research

Start date: May 2024
Phase:
Study type: Observational

Participation in clinical trials usually favors a particular demographic group. But there is limited research available to explain what study attributes affect the completion of these specific demographic groups. This study will investigate the safety and efficacy of esophageal cancer treatments. The focus will be on tracking the rates of completion and withdrawal among these individuals. It will also try to analyze data from the perspective of different demographic groups to check for recurring trends which might yield insights for the sake of future esophageal cancer research.