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Erectile Dysfunction clinical trials

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NCT ID: NCT05823506 Recruiting - Clinical trials for Erectile Dysfunction

Efficacy and Safety of Focused Shockwave Therapy Plus Tadalafil vs Tadalafil Alone in Patient With Erectile Dysfunction

Start date: February 1, 2023
Phase: N/A
Study type: Interventional

The goal of this trial is that using tadalafil plus low-intensity extracorporeal shockwave therapy (li-ESWT) is more effective than using tadalafil alone in improving erection rigidity and sexual function. The efficacy of the combination of li-ESWT and tadalafil has been confirmed by a number of studies, including in patients after radical prostatectomy. However, this method is still not a "first-line" method in young primary patients and its benefits in combination with drugs for these patients are not obvious. The investigators assume that the combination of tadalafil plus low-intensity extracorporeal shockwave therapy (li-ESWT) will improve the subjective state of patients assessed by points of validated questionnaires and Number of successful intercourse per week.

NCT ID: NCT05765331 Recruiting - Clinical trials for Erectile Dysfunction

The Impact of Chatbot-aid on Promoting Self-management of Men's Health in the Post COVID-19 Era

Start date: January 2, 2023
Phase: N/A
Study type: Interventional

The AI chatbot as an artificial intelligence technology provides disease information and health care through digital assistance. However, the effectiveness of chatbot in promoting men's health in the field of urology needs further research to evaluate its actual results. The purpose of this study is to explore the impact of AI chatbot-aid intervention on enhancing self-management, and decision self-efficacy among men with lower urinary tract symptoms (LUTS) due to an enlarged prostate, and with or without erectile dysfunction (ED) in the post COVID-19 era.

NCT ID: NCT05749354 Recruiting - Clinical trials for Erectile Dysfunction

Clinical Efficacy of Acupuncture on the Liver Meridian in Men With Erectile Dysfunction Reserve

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Start date: January 11, 2023
Phase: N/A
Study type: Interventional

Erectile dysfunction (ED) is a kind of worldwide and common sexual dysfunction disease, which mainly affects men over forty years old. The clinical characteristics of ED is the inability to maintain sufficient erection to obtain satisfactory sexual intercourse. Age, education, diabetes, stroke, obesity, and hypertension are factors inducing ED. Recent years, the prevalence of ED is rising, and more men aged below forty years old are suffering ED. Published review indicated that the prevalence of ED was 40.56% in Chinese men aged over forty years old. A survey conducted in China suggested that 40.56% men aged over forty years old suffered from ED. Another international survey found that, 21.48% sexually active participants suffered from ED. Several researches demonstrated that, ED affects health and quality of life of patients and partner. Besides, ED induces patients' psychosocial problems, including depression and anxiety, and reduce work efficiency. According to American Urological Association guideline published in 2018, the clinical therapies for ED include phosphodiesterase type 5 inhibitor (PDE5i), vacuum erection device, and penile prosthesis implantation. PDE5i (such as sildenafil, vardenafil, and tadalafil) is a first-line drug for ED, recommended by doctors and patients. However, the most common side effects of PDE5i were headache, dyspepsia, flushing, and blurred vision. Furthermore, the ideal dose and type of PDE5i still need to be further studied. The use of PDE5i is restricted by those reasons. Acupuncture is an important role of Traditional Chinese Medicine (TCM), and acupuncture received more concerned recently. The correlation between meridians and viscera is the center of acupuncture scientific problem. Acupoints stimulation can regulate visceral sensation and mobility to treat diseases.

NCT ID: NCT05673005 Recruiting - Clinical trials for Erectile Dysfunction Following Radical Prostatectomy

MED3000 Topical Gel for On-Demand Treatment of Post-Radical Prostatectomy Erectile Dysfunction

Start date: April 1, 2023
Phase: N/A
Study type: Interventional

The investigators are doing this research to evaluate the efficacy and safety of topical MED3000 therapy in men with persistent erectile dysfunction 1.5 to 4 years following radical prostatectomy surgery.

NCT ID: NCT05650866 Recruiting - Clinical trials for Erectile Dysfunction Following Radical Prostatectomy

Safety and Tolerability of a Novel Implantable Device for the Treatment of Erectile Dysfunction

Start date: May 19, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to assess if a new device is safe to use as a potential treatment for erectile dysfunction following radical prostatectomy. The main questions it aims to answer are: - Is the device safe? - Does the device works well? Are the participants satisfied with the device? Participants will be implanted with the device during the ongoing prostatectomy surgery and will be asked to complete the following tasks during 6 months follow-up: - Come to the hospital for follow-up visits, - Complete questionnaires, - Activate the device every day, - Measure erection hardness. Researchers will compare an implanted group (participants having the device) with a control group (participants not having the device) to see if the device works well.

NCT ID: NCT05632042 Recruiting - Metabolic Syndrome Clinical Trials

Response of Metabolic Syndrome and Sexual Dysfunction to Lifestyle Changes in Men With Psoriasis

Start date: October 16, 2022
Phase: N/A
Study type: Interventional

complaint of sexual dysfunction and metabolic syndrome are highly reported in men with psoriasis

NCT ID: NCT05624086 Recruiting - Hepatitis C Clinical Trials

Hepatic Enzymes, Psychological Measures, and Sexual Dysfunction Responses to Aerobic Exercise in Hepatitis-C Men

Start date: October 15, 2022
Phase: N/A
Study type: Interventional

Chronic hepatitis C virus (HCV) infection is a systematic disease that affects several aspects of patients' well-being, including physical, mental, social, and sexual quality of life. In recent years, this clinical trial aims to search the Response of Hepatic Enzymes, Psychological Measures, and Sexual Dysfunction to Aerobic Exercise in Hepatitis Men With Sexual Dysfunction Complaint

NCT ID: NCT05615454 Recruiting - Clinical trials for Multiple Sclerosis, Relapsing-Remitting

Effect of Bio-electromagnetic Energy Regulation Therapy on Erectile Dysfunction in Patients With Multiple Sclerosis

Start date: February 28, 2023
Phase: N/A
Study type: Interventional

Multiple sclerosis (MS) is an inflammatory disease that affects the brain and spinal cord. There are potential impacts on neurological functions, including sensory and autonomic functions. The Primary observed in males with MS is erectile dysfunction (ED), which substantially impacts the quality of life. There is increasing literature on electromagnetic fields' biological and clinical effects, particularly on ED.

NCT ID: NCT05574868 Recruiting - Clinical trials for Erectile Dysfunction

Rigicon Infla10® Three-Piece Inflatable Penile Prosthesis (ERASE ED)

Start date: July 11, 2022
Phase: N/A
Study type: Interventional

This study evaluates the long-term safety and efficacy of the use of the Rigicon Infla 10® Three-Piece Inflatable Penile Prosthesis in patients with erectile dysfunction. This study follows patients implanted with the Rigicon Infla 10® Three-Piece Inflatable Penile Prosthesis for up to 3 years after implantation. This study will take approximately 6 months to enroll all subjects. (14 days, 1 month, 6 months, 12 months,18 months, 24 months, and 36 months, post-procedure. ) Subjects will be followed per protocol and institutional standard of care for ED and comorbidities.

NCT ID: NCT05558007 Recruiting - Prostate Cancer Clinical Trials

Safety and Efficacy Evaluation of BZ371A Topically Applied on Prostatectomized Patients

Start date: November 22, 2023
Phase: Phase 2
Study type: Interventional

To determine efficacy, safety and tolerabiltiy of topically applied BZ371A in patients that experienced RP, in combination with daily tadalafil compared to placebo.