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NCT03646682 Clinical Trial

Pharmakokinetik of Caffeine in Epiretinal Membranes After Oral Intake: a Pilot Study

Epiretinal Membrane Clinical Trial

Official title:
Pharmakokinetik of Caffeine in Epiretinal Membranes After Oral Intake: a Pilot Study

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT03646682
Other study ID # CaffERM
Secondary ID
Status Completed
Phase N/A
First received
Last updated
Start date August 13, 2018
Est. completion date December 1, 2019

Study information
Verified date March 2020
Source Vienna Institute for Research in Ocular Surgery
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Caffeine concentrations in the vitreous Body and exzised epiretinal membranes are measured by gas-chromatography/mass spectrometry.

Description:

Caffeine concentrations in the vitreous Body and exzised epiretinal membranes are measured by gas-chromatography/mass spectrometry. One hour before surgery patients in the caffeine Group will receive 180mg of caffeine. in all patients vitrectomy with Membrane Peeling will be performed, due to epiretinal membranes

Recruitment information / eligibility
Status Completed
Enrollment 40
Est. completion date December 1, 2019
Est. primary completion date December 1, 2019
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria:

- epiretinale membrane

Exclusion Criteria:

- none

Study Design

Related Conditions & MeSH terms

Intervention

Procedure:
• vitrectomy with membrane peeling
during vitrectomy with membrane peeling a prob of the vitreous body and the excised epiretinal membrane will be harvested for gas-chromatography/mass spectrometry

Locations
Country Name City State
Austria Vienna Institute for Research in Ocular Surgery (VIROS), Hanusch Hospital Vienna Vienna

Sponsors (1)
Lead Sponsor Collaborator
Vienna Institute for Research in Ocular Surgery

Country where clinical trial is conducted

Austria, 

Outcome
Type Measure Description Time frame Safety issue
Primary concentration of caffeine in vitreous probes and epiretinal membranes concentration of caffeine in the probes will be measuread by gas-chromatography/mass spectrometry one hour
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