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Epiretinal Membrane clinical trials

View clinical trials related to Epiretinal Membrane.

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NCT ID: NCT06232616 Enrolling by invitation - Epiretinal Membrane Clinical Trials

Vitrectomy Combined With Intravitreal Dexamethasone Implant for Idiopathic Epiretinal Membrane With Macular Oedema

Start date: March 11, 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to evaluate the efficacy and safety of 25-gauge pars plana vitrectomy combined with intravitreal dexamethasone implant for the treatment of idiopathic epiretinal membrane with cystoid macular oedema. The main questions it aims to answer are: - mean changes in best corrected visual acuity and central macular thickness from baseline to post-operative 24 weeks - mean change in proportion of cystoid macular oedema area from baseline to post-operative 24 weeks - intraocular pressure throughout postoperative 24 weeks - concentrations of inflammatory factors in vitreous samples Participants will undergo a standard three-port 25-gauge pars plana vitrectomy and epiretinal membrane peeling combined with phacoemulsification, aspiration, and intraocular lens implantation. The dexamethasone implant will be injected into the vitreous cavity at the end of the operation.

NCT ID: NCT06040216 Completed - Epiretinal Membrane Clinical Trials

Evolution of EIFL Following PPV

Start date: January 15, 2020
Phase:
Study type: Observational

Various classification systems have been described for epiretinal membrane (ERM). One of them is a new OCT-based staging scheme based on displacement and reorganization of inner retinal layers called ectopic inner retinal layers (EIFL). We evaluated pre-and perioperative factors related to time for evolution of EIFL.

NCT ID: NCT05860985 Recruiting - Retinal Detachment Clinical Trials

Zeiss RESIGHT Disposable Lenses Evaluation Study

RESIGHT
Start date: April 11, 2023
Phase: N/A
Study type: Interventional

To evaluate the intra-operative efficacy of a new intra-operative viewing device.

NCT ID: NCT05747144 Recruiting - Retinal Detachment Clinical Trials

Multimodal Imaging in Vitreo-retinal Surgery and Macular Dystrophies

MICAI
Start date: January 15, 2021
Phase:
Study type: Observational

The aim of the study is to identify morphological and functional biomarkers of post-operative recovery after vitreoretinal surgery, using decisional support systems (DSS), based on multimodal big-data analysis by means of machine learning techniques in daily clinical practice

NCT ID: NCT05710458 Completed - Retinal Detachment Clinical Trials

Performance Comparison of the 25 Gauge 20,000cpm HYPERVIT Dual Blade vs. 10,000cpm ULTRAVIT Vitrectomy Cutter

Start date: July 1, 2021
Phase: N/A
Study type: Interventional

This prospective randomised controlled trial will be conducted to investigate that increasing the vitrectomy cutting rate from 10,000 cut/min to 20,000 cut/min will result more efficiency and shorter core vitrectomy time, and it is equally safe as compared to the current 10,000 cut/min. We plan to target the patients undergoing for vitrectomy for common vitreoretinal pathology. Our plan is to conduct a randomised study with 2 arms, one with the higher cutting rate (20,000 cut/min) versus a second arm using the existing system 10,000 cuts/min.

NCT ID: NCT05588037 Recruiting - Cataract Clinical Trials

Combined Vitrectomy and Femtosecond Laser-assisted Cataract Surgery

Start date: January 1, 2017
Phase: N/A
Study type: Interventional

Based on the progress of cataract surgery, intraocular lens development, vitreoretinal surgery and anesthesia technology in recent years, the purpose of this study is to develop a new type of more accurate and minimally invasive combined surgery for cataract and fundus diseases, and to evaluate the advantages and value of the surgery as well as related complications, so as to minimize the surgical trauma and obtain faster visual function recovery and better patient comfort. To provide new solutions for the growing demand of eye health care.

NCT ID: NCT05517473 Completed - Macular Holes Clinical Trials

Efficacy and Safety Evaluation of MONOBLUE DUAL View and MONOBLUE ILM View Vital Stains

NewBlueDyes
Start date: July 5, 2022
Phase:
Study type: Observational

In this study, the investigators aim to collect data regarding the efficiency and safety of two dyes used intraoperatively in vitrectomy to stain intraocular tissues. These products have the necessary approvals to use during such operation,These are NOT experimental products.

NCT ID: NCT05494242 Completed - Ophthalmopathy Clinical Trials

Single Superior ILM/ERM Flap for the FTMH.

Start date: September 1, 2022
Phase: N/A
Study type: Interventional

In this study, the investigators will make the only upper flap either from the internal limiting membrane or from the epiretinal membrane to cover the full thickness macular hole.

NCT ID: NCT05416827 Not yet recruiting - Epiretinal Membrane Clinical Trials

Evaluation of Intraoperative Slow-release Dexamethasone Implant for Epiretinal Membrane

Start date: June 15, 2022
Phase: N/A
Study type: Interventional

Epiretinal membrane (ERM) is a commonly encountered vitreoretinal interface anomaly with a prevalence of approximately 10% in the adult population. It is often treated with pars plana vitrectomy (PPV) and membrane peeling when symptomatic. PPV is generally successful at improving visual acuity (VA) and/or metamorphopsia. At times, however, visual recovery can be hindered by macular edema in the post-vitrectomy period. Ozurdex can accelerate the resorption of intraretinal edema and hasten the improvement in the visual acuity. It has been shown to facilitate fluid absorption by both stimulating endogenous adenosine signaling in Muller cells and by down regulating vascular endothelial growth factor production. So, this study aim to investigate the efficacy of Ozurdex implant after PPV in epiretinal membrane eyes.

NCT ID: NCT05287269 Completed - Clinical trials for Age Related Macular Degeneration

Ocular Coherence Tomography During Cataract Assessment

Start date: November 2, 2020
Phase:
Study type: Observational [Patient Registry]

Many patients will have underlying maculopathy present when undergoing cataract surgery, which are not visible on fundoscopy alone. Knowledge of this underlying pathology will allow an improved consenting process and discussion with the patient regarding the risks, visual prognosis and recovery following cataract surgery. Incidental findings in the fellow eye would also allow for improved diagnosis and management of these patients without adding significant additional time to specialist high volume cataract assessment clinics.