Epiretinal Membrane Clinical Trial
Official title:
Morphologic and Functional Results After Phacoemulsification and 25 Gauge Vitrectomy Versus Phacoemulsification Only in Eyes Affected by Idiopathic Epiretinal Membranes
The purpose of the study is to evaluate the difference in Early Treatment Diabetic Retinopathy Study (ETDRS) visual acuity, oct retinal thickness and microperimetry in 2 groups of 30 eyes each affected by idiopathic epiretinal membranes that underwent phacoemulsification and 25G pars-plana vitrectomy with internal limiting membrane (ILM) peeling (Group 1) versus phacoemulsification only (Group 2), with a follow-up length up to 5 years.
Idiopathic epiretinal membranes represent a common cause of visual loss in elderly population. Vitrectomy with membrane peeling is nowadays considered the gold standard in the management of such pathology, with very good results either at short-time or at long-time follow up. In case of mild visual impairment due to epiretinal membrane and associated cataract, it is reasonable to treat only the lens pathology (with phacoemulsification and intra-ocular lens (IOL) implantation). In case of symptoms or ophthalmoscopic finding worsening it is always possible to submit patients who only underwent cataract surgery to vitrectomy with membrane peeling. There are, by now, no comparative studies between these two different approaches in medical literature. ;
Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT03332758 -
Inflammasomes in Cell Death in FTMH, ERM, and RRD
|
||
| Active, not recruiting |
NCT04130841 -
Effects of Internal Limiting Membrane Peeling on Visual Function in Epiretinal Membrane Surgery
|
N/A | |
| Recruiting |
NCT03713268 -
Intraoperative OCT Guidance of Intraocular Surgery II
|
||
| Terminated |
NCT01532765 -
Randomized Trial Comparing Epiretinal Membrane Surgery With and Without Internal Limiting Membrane Removal
|
N/A | |
| Completed |
NCT01474655 -
Retinal Layers and Visual Rehabilitation After Epiretinal Membrane Removal
|
N/A | |
| Active, not recruiting |
NCT04120311 -
Episcleral Dexamethasone for Treatment of Macular Edema and Inflammatory Disorders of the Posterior Pole
|
Phase 1 | |
| Completed |
NCT04445142 -
Fovea ERM After Fovea-sparing ILM Peeling
|
||
| Recruiting |
NCT01701518 -
A Pilot Study of the Effectiveness of Intra-operative Ozurdex® in Vitrectomy Surgery for Epiretinal Membranes
|
N/A | |
| Completed |
NCT01627977 -
Association of Lutein, Zeaxanthin and Brilliant Blue in Chromovitrectomy
|
Phase 3 | |
| Completed |
NCT00408720 -
Comparison of a Spectral OCT/SLO With the Stratus OCT for Imaging Various Retinal Pathologies
|
N/A | |
| Completed |
NCT05171621 -
Measuring Subjective Quality of Vision and Metamorphopsia Before and After Epiretinal Membrane and Macular Hole Surgery
|
||
| Recruiting |
NCT04306718 -
Cultivation of Hyalocytes From ILM and ERM Samples: a Pilot Study
|
N/A | |
| Recruiting |
NCT01985490 -
Change in Foveal Avascular Zone After Removal of Epiretinal Membrane and Internal Limiting Membrane
|
N/A | |
| Completed |
NCT01238393 -
Treatment of Epiretinal Membranes With Ranibizumab
|
N/A | |
| Terminated |
NCT00333060 -
Study of OT-551 Eye Drops to Prevent or Delay Progression of Nuclear Cataracts Following Vitreous Removal
|
Phase 2 | |
| Completed |
NCT05287269 -
Ocular Coherence Tomography During Cataract Assessment
|
||
| Recruiting |
NCT05138315 -
Quantification of Metamorphopsia in Patients With Epiretinal Membranes
|
N/A | |
| Recruiting |
NCT03661593 -
Aniseikonia in Epiretinal Membrane Patients
|
N/A | |
| Completed |
NCT03457584 -
Effect of Air-tamponade on Intraretinal Cystoid Changes After Membrane Peeling
|
N/A | |
| Terminated |
NCT04802265 -
EpiRetinal Membrane Peeling and Internal Limiting Membrane
|