Clinical Trials Logo
  1. Home
  2. Epiretinal Membrane
  3. NCT03457584
  4. Details
NCT03457584 Clinical Trial

Effect of Air-tamponade on Intraretinal Cystoid Changes After Membrane Peeling

Epiretinal Membrane Clinical Trial

Official title:
Effect of Air-tamponade on Intraretinal Cystoid Changes After Vitrectomy With Membrane Peeling

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT03457584
Other study ID # cysMP
Secondary ID
Status Completed
Phase N/A
First received
Last updated
Start date November 1, 2017
Est. completion date December 1, 2019

Study information
Verified date September 2020
Source Vienna Institute for Research in Ocular Surgery
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Patients with intraretinal cystoid changes before scheduled membrane peeling for epiretinal membranes are included. Patients are randomized for balanced salt solution (BSS) or air-tamponade.

Description:

Patients with intraretinal cystoid changes before scheduled membrane peeling for epiretinal membranes are included. 23G-pars plana vitrectomy with membrane peeling is performed in all patients. Before surgery patients are randomized for BSS or air-tamponade. Optical coherence tomography (OCT) is performed 5 days after and 3 months after surgery, visual acuity is measured 3 months after surgery.

Recruitment information / eligibility
Status Completed
Enrollment 96
Est. completion date December 1, 2019
Est. primary completion date December 1, 2019
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria:

- epiretinal membranes and intraretinal cystoid changes

Exclusion Criteria:

- macular edema due to other reason than epiretinal membrane

- hereditary ocular disease

- pregnancy

Study Design

Related Conditions & MeSH terms

Intervention

Procedure:
• air arm
epiretinal membranes are excised during membrane peeling and air-tamponade is left in the eye
• BSS arm
epiretinal membranes are excised during membrane Peeling and BSS is left in the eye

Locations
Country Name City State
Austria VIROS - Vienna Institute for Research in Ocular Surgers - Departement of Opthalmology - Hanusch Hospital Vienna

Sponsors (1)
Lead Sponsor Collaborator
Vienna Institute for Research in Ocular Surgery

Country where clinical trial is conducted

Austria, 

Outcome
Type Measure Description Time frame Safety issue
Primary resorption of intraretinal cystoid changes after surgery occurrence of intraretinal cystoid changes will be diagnosed by OCT 3 months
See also
  Status Clinical Trial Phase
Completed NCT03332758 - Inflammasomes in Cell Death in FTMH, ERM, and RRD
Active, not recruiting NCT04130841 - Effects of Internal Limiting Membrane Peeling on Visual Function in Epiretinal Membrane Surgery N/A
Recruiting NCT03713268 - Intraoperative OCT Guidance of Intraocular Surgery II
Terminated NCT01532765 - Randomized Trial Comparing Epiretinal Membrane Surgery With and Without Internal Limiting Membrane Removal N/A
Completed NCT01474655 - Retinal Layers and Visual Rehabilitation After Epiretinal Membrane Removal N/A
Active, not recruiting NCT04120311 - Episcleral Dexamethasone for Treatment of Macular Edema and Inflammatory Disorders of the Posterior Pole Phase 1
Completed NCT04445142 - Fovea ERM After Fovea-sparing ILM Peeling
Recruiting NCT01701518 - A Pilot Study of the Effectiveness of Intra-operative Ozurdex® in Vitrectomy Surgery for Epiretinal Membranes N/A
Completed NCT01627977 - Association of Lutein, Zeaxanthin and Brilliant Blue in Chromovitrectomy Phase 3
Completed NCT01771939 - Phacoemulsification and 25 Gauge (25G) Vitrectomy Versus Phacoemulsification Only in Idiopathic Epiretinal Membranes N/A
Completed NCT00408720 - Comparison of a Spectral OCT/SLO With the Stratus OCT for Imaging Various Retinal Pathologies N/A
Completed NCT05171621 - Measuring Subjective Quality of Vision and Metamorphopsia Before and After Epiretinal Membrane and Macular Hole Surgery
Active, not recruiting NCT04306718 - Cultivation of Hyalocytes From ILM and ERM Samples: a Pilot Study N/A
Recruiting NCT01985490 - Change in Foveal Avascular Zone After Removal of Epiretinal Membrane and Internal Limiting Membrane N/A
Completed NCT01238393 - Treatment of Epiretinal Membranes With Ranibizumab N/A
Terminated NCT00333060 - Study of OT-551 Eye Drops to Prevent or Delay Progression of Nuclear Cataracts Following Vitreous Removal Phase 2
Completed NCT05287269 - Ocular Coherence Tomography During Cataract Assessment
Recruiting NCT05138315 - Quantification of Metamorphopsia in Patients With Epiretinal Membranes N/A
Recruiting NCT03661593 - Aniseikonia in Epiretinal Membrane Patients N/A
Terminated NCT04802265 - EpiRetinal Membrane Peeling and Internal Limiting Membrane