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Epilepsy clinical trials

View clinical trials related to Epilepsy.

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NCT ID: NCT02284854 Completed - Epilepsy Clinical Trials

Pharmacokinetic Interaction Study Between Eslicarbazepine Acetate and Carbamazepine

Start date: July 2009
Phase: Phase 1
Study type: Interventional

Open-label study in two parallel groups of 20 healthy subjects each. Group A assessed the effect of CBZ on ESL pharmacokinetics, and Group B assessed the effect of ESL on CBZ pharmacokinetics.

NCT ID: NCT02284828 Completed - Epilepsy Clinical Trials

Effects of Eslicarbazepine Acetate (BIA 2-093) on Cognition and Psychomotor Function

Start date: September 2007
Phase: Phase 1
Study type: Interventional

Single-blind, single-centre, fixed-order study to evaluate the PD effects of a single oral dose and multiple oral doses of ESL (BIA 2-093) in healthy volunteers.

NCT ID: NCT02283840 Completed - Epilepsy Clinical Trials

Single Dose Crossover Comparative Bioavailability Study of Eslicarbazepine Acetate Versus To-be-marketed Formulation

Start date: May 2007
Phase: Phase 1
Study type: Interventional

Single center, randomized, single dose, laboratory-blinded, 2-period, 2-sequence, crossover design

NCT ID: NCT02283827 Completed - Epilepsy Clinical Trials

Open-label Drug Interaction Study Between Eslicarbazepine Acetate and Phenytoin.

Start date: January 2007
Phase: Phase 1
Study type: Interventional

Single centre, open-label, multiple doses, two parallel study groups each receiving two formulations in a one-sequence design

NCT ID: NCT02283814 Completed - Epilepsy Clinical Trials

A Open-label, Drug Interaction Study Between Eslicarbazepine Acetate and Topiramate

Start date: January 2007
Phase: Phase 1
Study type: Interventional

Single centre, open-label, multiple doses, one-sequence design study in two parallel groups of healthy volunteers

NCT ID: NCT02283801 Completed - Epilepsy Clinical Trials

Open-label Drug Interaction Study Between Eslicarbazepine Acetate and Lamotrigine.

Start date: November 2006
Phase: Phase 1
Study type: Interventional

Single centre, open-label, multiple doses, one-sequence design study in two parallel groups of healthy volunteers

NCT ID: NCT02283788 Completed - Epilepsy Clinical Trials

Trial to Evaluate the Effect of Eslicarbazepine Acetate on Cardiac Repolarization

Start date: March 2007
Phase: Phase 1
Study type: Interventional

A randomized, double-blind, placebo-controlled and open label active-controlled, 4 period crossover trial to evaluate the effect of eslicarbazepine acetate on cardiac repolarization in healthy adult men and women

NCT ID: NCT02281591 Completed - Epilepsy Clinical Trials

Disposition of Eslicarbazepine Acetate and Its Metabolites S-licarbazepine and R-licarbazepine

Start date: June 2006
Phase: Phase 1
Study type: Interventional

Single centre, open-label, randomised study in four parallel groups of healthy volunteers

NCT ID: NCT02281526 Completed - Epilepsy Clinical Trials

An Open-label, Multiple-dose, Single-centre Study, Investigating the Pharmacokinetics of BIA 2-093

Start date: May 2005
Phase: Phase 1
Study type: Interventional

Open-label, multiple-dose, single-centre study in 2 groups of subjects: subjects with moderate hepatic impairment and healthy controls. The trial consisted of a screening visit, a treatment phase and a follow-up visit. All subjects were to be treated with study medication for 8 consecutive days. Blood and urine were collected for the PK analysis, and safety assessments were performed.

NCT ID: NCT02281448 Completed - Epilepsy Clinical Trials

Effect of BIA 2-093 on the Pharmacokinetics of a Combined Oral Contraceptive.

Start date: March 2005
Phase: Phase 1
Study type: Interventional

Single centre, two-way crossover, randomised, open-label study in 20 healthy female volunteers.The volunteers received an oral single-dose of a combined contraceptive containing with an oral once daily dose of 1200 mg of BIA 2-093