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Sevelamer Hydrochloride in Peritoneal Dialysis Patients — SERENE  

Endstage Renal Disease Clinical Trial

Official title:
Use of Sevelamer Hydrochloride to Control Hyperphosphatemia and Reduce Calcification Burden in the Poor Peritoneal Dialysis Patients

Clinical Trial Summary

To test the hypothesis that second-line fixed low-dose sevelamer hydrochloride therapy is as effective as first-line high-dose sevelamer hydrochloride therapy in limiting the progression of cardiovascular calcification.

Clinical Trial Description

Cardiovascular disease accounts for nearly 50% of the mortality and is the most frequent cause of hospitalization in ESRD patients. Hyperphosphatemia is increasingly recognized to be an important predictor of mortality and cardiovascular death in ESRD patients and is largely attributed to the increased prevalence of vascular calcification. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00745589
Study type Interventional
Source The University of Hong Kong
Contact
Status Completed
Phase N/A
Start date July 2008
Completion date January 2015
View Details
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