Emphysema Clinical Trial
Official title:
Effects of Lung Volume Reduction Surgery in the Treatment of Severe Emphysema
Verified date | December 2004 |
Source | VA Office of Research and Development |
Contact | n/a |
Is FDA regulated | No |
Health authority | United States: Federal Government |
Study type | Interventional |
The main objectives of this study are to see if a type of lung surgery, known as lung reduction surgery, in addition to standard medical treatment improves the quality of life, lung function, and reduces the high mortality associated with severe emphysema when compared to standard medical treatment alone. Another goal of this study is to better identify the patients most likely to benefit from this surgical treatment. The information obtained in this study is important because lung reduction surgery is being done in several centers around the country but its long term benefits, if any, over standard medical treatment, are not known.
Status | Completed |
Enrollment | 0 |
Est. completion date | September 2002 |
Est. primary completion date | |
Accepts healthy volunteers | No |
Gender | Male |
Age group | N/A to 75 Years |
Eligibility |
1. Post-bronchodilator FEV I < 40% and > 15% of predicted 2. TLC > 120% of predicted* 3. Carbon monoxide diffusing capacity by the single breath technique (DLCOSB) < 50% of predicted 4. PaCO2 < 55 mmHg 5. Age 75 years or younger - TLC will be determined by body plethysmography using slow inspiratory effort to determine thoracic gas lume because of the overestimation of lung volumes by high frequency panting in patients with COPD. |
Allocation: Randomized, Endpoint Classification: Efficacy Study, Primary Purpose: Treatment
Country | Name | City | State |
---|---|---|---|
United States | Veterans Affairs Medical Center | Houston | Texas |
Lead Sponsor | Collaborator |
---|---|
VA Office of Research and Development |
United States,
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