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Emergencies clinical trials

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NCT ID: NCT05357365 Active, not recruiting - Clinical trials for Occupational Diseases

Establishing a Cohort for Occupational Disease of Emergency Medical Workers

Start date: May 9, 2022
Phase:
Study type: Observational

This study aims to understand the epidemiological characteristics, related factors , and current status of occupational diseases and damage that occur in emergency medical workers (doctors and nurses). A number of surveys were conducted on about 100 emergency medical workers for about a year with occupational factors, physical health, and mental health.

NCT ID: NCT05296590 Active, not recruiting - Sepsis Clinical Trials

Monocyte Distribution Width (MDW) in the General Population of Emergency Department Patients With and Without Bacteremia

Start date: July 1, 2021
Phase:
Study type: Observational

This project will evaluate the usefulness of Monocyte Distribution Width (MDW) for the diagnosis of blood culture positivity (BSI) in patients in the Emergency Department (ED) and reevaluate the usefulness of MDW in patients with BSI and sepsis. Consequently, if MDW indicate a high likelihood of bacteremia antibiotic management in patients with suspected bacterial infections will be changed and aid appropriate antibiotic administration.

NCT ID: NCT05290753 Active, not recruiting - Clinical trials for Prokinetic Use After Emergency Intestinal Anastomosis

Impact of Prokinetic Use After Emergency Intestinal Anastomosis on Postoperative Clinical Outcomes

Start date: January 1, 2022
Phase: N/A
Study type: Interventional

Prokinetic drugs used to accelerate healing of intestinal anastomosis of urgent cases which not prepared preoperative by increase intestinal motility and gastric emptying and decrease postoperative adhesions They are many types of prokinetics as cholinergic agonists, dopamine antagonist, serotonergic agonists and macrolides Agents of prokinetics administered immediately post operation and at the time of hospitalization

NCT ID: NCT05281627 Active, not recruiting - Clinical trials for Emergency Laparotomy

Psycho-Social Outcomes Following Emergency Laparotomy

POLO
Start date: October 15, 2021
Phase:
Study type: Observational

An emergency laparotomy (EmLap) is a life-saving operationÍž but the aftermath for those that do survive can be lifechanging. Each year, in excess of 25,000 EmLaps are performed in UK. A national effort, through the National Emergency Laparotomy Audit (NELA), has managed to improve peri-operative care, and reduce 30 day mortality from 1 in 4 to less than 1 in 10. Whilst this reduction should be commended, it also means that more patients are surviving with some form of new infirmity. This infirmity may be short-lived and reversible in some, and yet others may transition into a permanent chronic disease state. The impact of EmLap on those individuals that "do not fully recover" is far-reaching and often interlinked, covering biological, social and psychological domains. This makes it difficult to describe the true problem, i.e. holistic morbidity and suggest an intervention to improve it. The primary aim of this work is to describe the holistic morbidity of EmLap throughout the first year of a patient's recovery.

NCT ID: NCT05235178 Active, not recruiting - Aortic Dissection Clinical Trials

The Effect of the CytoSorb® Filter to Remove Anticoagulants From the Circulation During Emergency Surgery for Aortic Dissection

Citron
Start date: April 18, 2021
Phase:
Study type: Observational

The direct oral anticoagulants (DOACs) and particularly the FXa inhibitors are a concern in patients presenting with type A aortic dissection as this may contribute to severe bleeding complications. The antidote andexanet alfa (Ondexxya®) can interact with the heparin- anti-thrombin III (ATIII) complex which may neutralize the anticoagulant effect of heparin and the use of andexanet alfa before surgery necessitating heparin-anticoagulation has been reported to cause unresponsiveness to heparin. The investigators have preliminary in-vitro data demonstrating the ability to remove apixaban from reconstituted blod by hemadsorption and are now analyzing if aFXa inhibitor levels may be reduced by hemadsorption in the clinical setting analyzing this in patients using FXa inhibitors being operated acutely for type A aortic dissection.

NCT ID: NCT05221697 Active, not recruiting - Emergencies Clinical Trials

Effect of an ML Electronic Alert Management System to Reduce the Use of ED Visits and Hospitalizations

Start date: September 1, 2020
Phase: N/A
Study type: Interventional

Development, validation and impact of an alert management system using social workers' observations and machine learning algorithms to predict 7-to-14-day alerts for the risk of Emergency Department (ED) Visit and unplanned hospitalization. Multi-center trial implementation of electronic Home Care Aides-reported outcomes measure system among patients, frail adults >= 65 years living at home and receiving assistance from home care aides (HCA).

NCT ID: NCT05176015 Active, not recruiting - Stroke, Acute Clinical Trials

Nystagmus Assessment for Patients Consulting in the Emergency Department for Acute Vertigo

Start date: January 15, 2022
Phase: N/A
Study type: Interventional

This pilot study is perfomed to validate and document faisability of the use of Frenzel lens and the use of a diagnostic algorithm for the assessment of a special sign (nystagmus) observe in the eyes of patients consulting in the emergency department (ED) for an acute episode of vertigo/dizziness/imbalance.

NCT ID: NCT05155202 Active, not recruiting - Clinical trials for Hypoxemic Respiratory Failure

Clinical Relevance of Nicardipine Induced Hypoxemia in the Intensive Care Unit

ECRHIN-ICU
Start date: November 15, 2021
Phase:
Study type: Observational

In the context of postoperative hypertension in the intensive care units, or after resusitation of hypertensive patients, intravenous antihypertensive drugs are often used. Among those drugs, Nicardipine is an effective drug, but with side effects such as inhibition of pulmonary vasoconstriction. Only preclinical studies have investigated the pathophysiology of this mechanism, and no clinical study have proven its clinical relevance. The aim of this study is to establish the incidence of Nicardipine induced hypoxemia and to compare it to another antihypertensive agent, Urapidil.

NCT ID: NCT05122663 Active, not recruiting - Dizziness Clinical Trials

Emergency Department Vestibular Rehabilitation Therapy for Dizziness and Vertigo

ED-VeRT
Start date: November 16, 2021
Phase:
Study type: Observational

ED-VeRT will enroll up to 125 adult emergency department (ED) patients presenting with a chief complaint of dizziness or vertigo to collect longitudinal outcomes over 3 months of follow-up. This will include 50 patients who were evaluated by an ED physical therapist (ie, vestibular rehabilitation) during their ED visit and 50 patients who received usual care. The aims of this trial are to: (1) obtain initial estimates of participant recruitment and retention, intra-cluster correlation, and between-group outcome differences that will inform sample size calculation for a future randomized clinical trial, and (2) assess feasibility and fidelity of a clinical classification protocol for undifferentiated dizziness among patients receiving ED vestibular rehabilitation.

NCT ID: NCT05116631 Active, not recruiting - Dental Clinical Trials

Evaluation of Emergency Department Visits and Activity : Study

EOTDES
Start date: October 1, 2021
Phase:
Study type: Observational

The main objective will be to evaluate the type of care performed and the main reasons for consulting patients for an odontological emergency in order to better adapt to the flow and expectations of patients.