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NCT ID: NCT06447584 Recruiting - Acute Poisoning Clinical Trials

Clinical Spectrum and Outcome of Poisoning in Children Admitted to the Pediatric Emergency and Intensive Care Units at Sohag University Hospital

Start date: June 1, 2024
Phase:
Study type: Observational

Acute poisoning is a major health problem that leads to emergent hospital admission.It has become the main factor that harms children and leads to disability and death of children. Also, it is still a serious issue in developing countries where it represents a common cause of emergency department presentation and admission. Acute poisoning can be divided into two categories (accidental and intentional),accidental poisoning is common in children under five years, whereas intentional poisoning is more common in adolescents, WHO estimated that, in 2016, accidental poisoning caused 106,683 deaths and the loss of 6.3 million years of healthy life. A study in Romania showed that intentional poisoning is the most common cause of poisoning among teenagers. Females are more vulnerable to suicidal or intentional poisoning than males. Medications, alcohol, and substance abuse are common poisoning agents among teenagers , another study at tertiary Indian hospital, pesticides, pharmaceutical drugs, and household products were the most common types of acute poisoning. Pesticides were reported as a cause of intentional and accidental poisoning. In agricultural areas, people were poisoned accidentally by pesticides that may be used for suicidal attempts because of their availability. Pharmaceutical drugs are also used for intentional poisoning due to the availability of street drugs and over-the-counter medications. Accidental poisoning by household products were observed in children and the most common products are hydrocarbon and naphthalene In Egypt acute poisoning represents a significant proportion of emergency visits of children and young people. This labors a burden on healthcare, society and economy and thus, it drain-s resources and multiplies workload . In fact, it is a preventable cause of morbidity and mortality. Children poisoning is a result of multiple risk factors including social, demographic, and industrial factors. Insufficient public awareness, easy accessibility to poison, negligence of caregivers, technological and industrial advances and even the nature of the environment are of the main causes.

NCT ID: NCT06420206 Recruiting - Lung Cancer Clinical Trials

Goals of Care Discussion for Patients With Advanced Lung and Gastrointestinal Cancer in the Emergency Department of a Comprehensive Cancer Center

Start date: May 14, 2024
Phase: N/A
Study type: Interventional

To improve quality of life for participants with advanced cancer, support their families, and lower overall cost of care.

NCT ID: NCT06406972 Recruiting - Suicide Clinical Trials

Brief Admission by Self-referral for Individuals With Self-harm: Effects on Compulsory Care

Start date: September 15, 2010
Phase:
Study type: Observational [Patient Registry]

Brief Admission by self-referral (BA) is a standardized treatment model, providing patient-controlled and person-centered care. It was developed to reduce self-harm and compulsory care by promoting autonomy. Randomized clinical trials have not yielded significant between group differences with respect to inpatient care, including compulsory care. The major difficulty in evaluating BA is preventing the control group from cross-contamination, as in the implementation process of BA, all physicians, all inpatient and outpatient staff as well as managers need to be informed and undergo basic education regarding the intervention. As BA addresses a prevalent and frustrating issue in psychiatric health care, there is considerable risk that the approach leaks to the control group, reducing the possibility to detect between-group differences. In the current study this will be addressed through a register-based approach, comparing similar clinics, implementing BA at different timepoints over time. Individuals with traits of borderline personality disorder will be included and comparisons will be made with respect to compulsory care, voluntary inpatient care and mortality.

NCT ID: NCT06404177 Recruiting - Traumatic Injury Clinical Trials

Enantyum® IV Versus Piroxen® IM in Emergency Pain Management

PiDex
Start date: July 15, 2023
Phase: Phase 3
Study type: Interventional

For pain of traumatic origin, the RICE protocol (Rest, Ice, Compression, Elevation) is the main therapeutic measure during the first 4 to 5 days post-trauma. However, there is currently insufficient evidence that this protocol is effective [4]. In the emergency department, paracetamol, NSAIDs or a combination of several molecules are generally prescribed. Patients even use these drugs without a prescription. The aim of this study is to Compare the effect of dexketoprofen® IV versus piroxen® IM in the treatment of pain in emergency departments.

NCT ID: NCT06400693 Recruiting - Airway Management Clinical Trials

Templates as Cognitive Aids in Emergency Airway Equipment Preparation: the Template Airway Trial

TemplateAirway
Start date: April 15, 2024
Phase: N/A
Study type: Interventional

Comparison of preparation times (in seconds) for emergency airway management (equipment only) with and without a template.

NCT ID: NCT06400602 Recruiting - Low Back Pain Clinical Trials

Health Coaching for Back Pain After Emergency Department Discharge

Start date: May 6, 2024
Phase: N/A
Study type: Interventional

The goal of this two-group randomized trial is to determine the feasibility and acceptability of a remotely-delivered health coaching intervention offered in conjunction with usual care for patients with an acute exacerbation of chronic low back pain who present to the emergency department (ED). The main questions this feasibility trial aims to answer are: - Is our health coaching intervention and randomized trial methodology feasible to conduct? - Is our health coaching intervention acceptable to participants and ED providers? Participants will be randomized to one of two groups (usual ED care plus health coaching or usual ED care plus education) and complete outcome assessments at 3 and 6 months after ED discharge. Participants and ED providers will also complete an interview.

NCT ID: NCT06366334 Recruiting - Suicidal Ideation Clinical Trials

Study of IV Ketamine for Emergency Department Treatment of Adolescent Suicidal Ideation

KSI
Start date: January 15, 2024
Phase: N/A
Study type: Interventional

Approximately 20% of Canadian adolescents experience thoughts of suicide, or suicidal ideation (SI), and suicide is the second leading cause of death among Canadians aged 15-19 years. The emergency department at CHEO sees approximately four patients per day with SI. Even though this is a medical emergency, there are no fast-acting treatments available. Ketamine is a medication that is commonly used to safely sedate children who require painful procedures in the emergency department. For nearly ten years, intravenous ketamine has also been shown to rapidly reduce SI in adults. However, ketamine as a treatment for SI has never been studied in adolescents. The primary study objective is to pilot a clinical trial that investigates intravenous ketamine to emergently treat SI in adolescents. If intravenous ketamine can relieve symptoms of SI for youth, this would have tremendous effects on patients and would dramatically change how physicians treat adolescent mental health emergencies. If ketamine is effective for several weeks, as it is in adults, it will help temporize patients until they receive more long-term psychiatric care. At the system level, it has the potential to reduce emergency visits and lengthy admissions. The investigators feel that the results of this study will be generalizable to pediatric centres across Canada and beyond.

NCT ID: NCT06362850 Recruiting - Cardiac Arrest Clinical Trials

Tele-Support for Emergency Medical Technicians

POHCA
Start date: April 8, 2024
Phase: N/A
Study type: Interventional

In this manikin-based simulation study the impact of tele-support during a simulated pediatric out-of-hospital cardiac arrest scenario on emergency medical technicians' guideline adherence, on gaze behavior as well as on performance of resuscitation management and cognitive load will be analyzed.

NCT ID: NCT06362525 Recruiting - Quality of Life Clinical Trials

Incidence of Episodes of (Dis)Connected Consciousness Among Emergency Patients Admitted in the Resuscitation Room

Start date: October 9, 2023
Phase:
Study type: Observational

This observational study aims to describe the incidence of episodes of disconnected consciousness (including near-death experience (NDE)) and episodes of connected consciousness in patients admitted to the resuscitation room, who survived a critical condition and who meet at least one of these criteria during their stay in the resuscitation room: (1) deep sedation, (2) intubation, (3) cardiopulmonary resuscitation, or (4) (non-drug-induced) Glasgow Coma Scale score = 3. We also investigate the potential (neuro)physiological markers and biomarkers. In order to help determine the potential risk factors of such episodes, cognitive factors such as dissociative propensity are also investigated. Unexpected visual and auditory stimuli will be displayed. In addition, we assess the evolution of memory, as well as short- and long-term consequences on quality of life, anxiety, and attitudes towards care. Memory of patients who did not meet the above-mentioned criteria are also investigated. A group of 15 healthy participants will be invited to test the stimuli display. Finally, (neuro)physiological parameters of a subsample of dying patients are also investigated.

NCT ID: NCT06360341 Recruiting - Acute Pain Clinical Trials

Emergency Department Digital Pain Self-Management Intervention to Improve Acute Low Back Pain Outcomes

Start date: April 15, 2024
Phase: N/A
Study type: Interventional

The proposed study aims to evaluate a pilot emergency department (ED) digital pain self-management intervention (EDPSI) focused on improving self-efficacy, knowledge, and skills, thus reducing the transition from acute to chronic low back pain in ED patients discharged with axial acute low back pain (aLBP). The proposed research has significant potential to improve self-efficacy (the confidence in one's ability to manage their condition) which is one of the most potent factors for improved health outcomes.