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Emergencies clinical trials

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NCT ID: NCT03377062 Not yet recruiting - CVA Clinical Trials

CVA in Patients Suffering From Decreased Consciousness, Confusion or Headaches to an Emergency Room

Start date: June 1, 2024
Phase:
Study type: Observational

A CVA occurs when there is a sudden interruption of blood supply to the brain. Fast identification of CVA is crucial in order to refer the patient to an appropriate medical center as well as to direct him/her to a suitable treatment upon arrival to the Medical Center, in order to minimize the permanent damage to the brain. In this study, we are evaluating a tool for detecting CVA based on EEG (electroencephalograph) data analysis using innovative algorithm. The system is comprised of four electrodes, reference electrode and earphones for auditory stimulation. In the study, 120 patients arriving to the emergency room with decreased consciousness, severe headaches or dizziness will be monitored for five-minute each, with EEG accompanied with auditory stimulation. The EEG analysis will be performed based on the synchronization of the front and back hemispheres. During CVA, specific hemisphere is damaged, therefore desynchronization is expected. The purpose of this study is to develop a tool for identifying CVA in patients who have no clear CVA related signs.

NCT ID: NCT03363880 Not yet recruiting - Trauma Clinical Trials

Establishment of Regional Severe Trauma Management System

Start date: January 1, 2018
Phase: N/A
Study type: Interventional

To evaluate the effects of trauma treatment team establishment on the treatment of patients with severe trauma.

NCT ID: NCT03252275 Not yet recruiting - Clinical trials for Maternal, Newborn and Child Health Emergencies

Peer Learning and HBB in Managing Maternal Newborn and Child Health Emergencies in Rural Uganda

SimForLife
Start date: August 30, 2017
Phase: N/A
Study type: Interventional

The aim of this study is to test an intervention that has potential to improve acute care skills and confidence related to safe delivery and newborn care for mid-level health providers in Uganda by the development of a 'mobile' simulation package including scale-up materials based upon research evidence. In this randomized study investigators will compare the impact of a peer learning package on skills, knowledge and team work regarding newborn care among health workers in rural south western Uganda.

NCT ID: NCT03238391 Not yet recruiting - Clinical trials for Contrast-induced Nephropathy

Ischemic Preconditioning for Prevention of Contrast Nephropathy in The Emergency Department

Start date: August 15, 2017
Phase: N/A
Study type: Interventional

The purpose of this study is to demonstrate the effectiveness of ischemic preconditioning in the emergency department to prevent contrast induced nephropathy

NCT ID: NCT03226665 Not yet recruiting - Obstruction Bowel Clinical Trials

Ultrasound Emergency Diagnosis of Small Bowel Obstruction

USBOW
Start date: November 1, 2018
Phase: N/A
Study type: Observational

Small bowel obstruction (SBO) is a common presentation to the emergency department (ED) and represents 15% of hospital admissions for acute abdominal complaints. Plain radiography, although traditionally recommended as the initial diagnostic imaging modality of choice, has a sensitivity of only 59% to 77%. When clinical and radiographic assessment is indeterminate, computed tomography (CT) becomes the test of choice due to its superior resolution and increased ability to identify both obstruction and its aetiology Aim: this is a prospective study in a sample of patients presenting to the emergency department (ED) with abdominal pain, vomiting, or other symptoms suggestive of a SBO (history of previous surgeries, constipation, abnormal bowel sounds, and abdominal distention). Patients will be evaluated with US prior to x-ray and CT, with possible diagnostic confirms by endoscopy or surgery.

NCT ID: NCT03154554 Not yet recruiting - Lumbar Pain Clinical Trials

Epidemiology of Patients Consulting for Original LBP Spinal Adult Emergency

Start date: June 2017
Phase: N/A
Study type: Observational

Lumbar pain is an extremely common complaint in general population. The direct and indirect costs incurred in are a real public health problem. Cohort studies show that improving symptoms after consultation for lumbar pain is insufficient, but there are few data on emergency medical and surgical services in France. In order to reflect on areas for improvement the investigators to carry out an inventory of consultations for lumbar pain emergencies of Hautepierre Hospital.

NCT ID: NCT03075293 Not yet recruiting - Pain Clinical Trials

Pain Management of Children With Appendicitis in the Emergency Department (ER)

Start date: March 26, 2017
Phase: N/A
Study type: Observational

The aim of this retrospective study is to determine the percentage of children with appendicitis who were given analgesics or opioids in the ER, to reduce their pain.

NCT ID: NCT03042065 Not yet recruiting - Asthma Clinical Trials

Salbutamol in the Pediatric Emergencies: Nebulization Estimated Via AerogeN or Jet

SIBILANT
Start date: March 2017
Phase: N/A
Study type: Interventional

Controlled trial of nebulized salbutamol using jet nebulizer or vibrating mesh technology in children presenting with acute moderate to severe asthma.

NCT ID: NCT02952430 Not yet recruiting - Emergencies Clinical Trials

Emergency Laparotomy and Frailty Study

ELF
Start date: December 2016
Phase: N/A
Study type: Observational

Patients aged over 65 comprise more than half the emergency general surgical workload, however, available risk-prediction tools for such patients are extrapolated from younger cohorts. Research suggests that high pre-operative frailty scores correlate with increased post-operative mortality and morbidity. Validated frailty assessments may help identify high risk older emergency surgical patients, facilitating decision-making and informing patient choice. We propose the first prospective UK observational study assessing frailty as an independent predictor of outcome in the older surgical patient undergoing emergency laparotomy. Prospective data collection of patients over 65 undergoing emergency laparotomy will be performed in 20 NHS Trusts. Pre-operative frailty scores will be evaluated using the Rockwood Frailty Scale. Primary outcome measure is 30-day mortality. Secondary outcome measures are post-operative complications, altered independence status and length of stay. Results will be disseminated at national/international surgical meetings and published in a peer-reviewed journal.

NCT ID: NCT02922686 Not yet recruiting - Wound Infection Clinical Trials

Penicillin for the Emergency Department Outpatient Treatment of CELLulitis

PEDOCELL
Start date: December 2016
Phase: Phase 4
Study type: Interventional

The main objective of this study is to investigate the non-inferiority of oral flucloxacillin alone compared with a combination of oral flucloxacillin and phenoxymethylpenicillin for the emergency department directed outpatient treatment of cellulitis, wound infections and abscesses, recently renamed by the Food and Drug Administration (FDA) as acute bacterial skin and skin structure infections (ABSSSIs). Half of the trial participants will receive flucloxacillin and placebo in combination, and the remaining half will be treated will flucloxacillin and phenoxymethylpenicillin. In a secondary objective the trial aims to measure adherence and persistence of trial patients with outpatient antibiotic therapy. In addition a within-trial evaluation of the cost per quality adjusted life year (QALY) gained from the use of oral flucloxacillin compared with combination therapy from the perspective of the health-care payer (direct costs) the patient and government. Finally the study will externally validate the Extremity Soft Tissue Infection-score, a Health Related Quality of Life (HRQL) questionnaire designed to quantify the impact of cellulitis, wound infections and abscesses on patient HRQL in clinical trials.