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Emergence Delirium clinical trials

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NCT ID: NCT06177847 Not yet recruiting - Anesthesia Clinical Trials

Efficacy of BIS Monitoring in Deep Hypnotic State

Start date: December 15, 2023
Phase: N/A
Study type: Interventional

Determining the efficacy of the BIS monitor in monitoring deep hypnotic states as well as intra- and post-operative outcomes in neurosurgery patients

NCT ID: NCT06176625 Active, not recruiting - Delirium Clinical Trials

Sight and Hearing Investigation Into Effects on Delirium

SHIELD
Start date: January 11, 2023
Phase: N/A
Study type: Interventional

The goal of this observational study is to learn about sensory loss in hospital patients with delirium. The main questions it aims to answer are: - Are hearing and vision loss related to increased risk of having delirium? - Do hearing and vision loss contribute to more severe delirium? - Do sensory loss and/or delirium affect patient satisfaction with hospital care? Participants will be asked to: - answer delirium screening questions, - undergo hearing & vision screenings, and - complete questionnaires about the hospital stay. The second part of this study is a clinical trial. Researchers will compare different hospital units to see if changing communication affects the number of patients with delirium. The main questions it aims to answer are: • Does sharing information about communication and/or providing hearing devices change the number of hospital patients with delirium? Participants in the study will be asked to complete delirium screenings and answer questions about their hearing and communication.

NCT ID: NCT06176144 Recruiting - Delirium Clinical Trials

Impact of Desflurane and Sevoflurane on Postoperative Delirium in Elderly Patients

Start date: September 10, 2023
Phase: N/A
Study type: Interventional

Advanced age is a consistent risk factor for the incidence of postoperative cognitive decline, which is associated with longer hospital stays, decreased quality of life, and increased mortality. Anaesthetic drugs can also affect postoperative cognition, as their residual effects can alter central nervous system activity. Desflurane and sevoflurane are widely used volatile anesthetics. Choice anesthetics may influence the occurrence of postoperative delirium. However, evidence in this aspect is conflicting.

NCT ID: NCT06164314 Not yet recruiting - Clinical trials for Postoperative Delirium

Perioperative Dexmedetomidine on Postoperative Delirium in Patients With Brain Tumors

Start date: January 25, 2024
Phase: N/A
Study type: Interventional

Neurosurgery is a risk factor for delirium. Dexmedetomidine might reduce delirium by reducing neuroinflammation, improving postoperative analgesia and sleep quality. The the primary hypothesis is that perioperative administration of dexmedetomidine can reduce the incidence of postoperative delirium

NCT ID: NCT06161662 Not yet recruiting - Anesthesia Clinical Trials

Effect of Acupoint Stimulation on Postoperative Delirium and Electroencephalogram

AS-DEEP
Start date: December 10, 2023
Phase: N/A
Study type: Interventional

Transcutaneous electrical acupoint stimulation (TEAS) was reported to benefit the patients undergoing surgeries by reducing anesthetics consumption and decreasing anesthesia related adverse effects. Electroencephalogram (EEG) and EEG-related indicators are important indicators reflecting the conscious state of the brain, and different anesthetic drugs and anesthesia depths cause different EEG characteristic changes. The mechanism by which TEAS improves postoperative delirium (POD) is not clear, and whether changes in EEG characteristic parameters is involved needs to be further explored. Therefore, this study aims to observe the effect of TEAS at Neiguan and Shenmen acupoint on POD in elderly patients undergoing abdominal surgery, and to explore the EEG related mechanism underlying TEAS improving POD.

NCT ID: NCT06138340 Recruiting - Clinical trials for Postoperative Delirium

The Effects of Anesthetics on Brain Network Connectivity in Patients With Supratentorial Glioma

Start date: August 31, 2023
Phase:
Study type: Observational

Perioperative anesthesia can affect postoperative cognitive function. In our previous study, intraoperative dexmedetomidine (Dex) infusion reduced the incidence of delirium within the first 5 days after brain tumor. However, the mechanism is still unclear. With the development of neuroimaging, multimodal neuroimaging technology provide a new method to explore the underlying mechanism. Therefore, the purpose of this study is to analyze the alterations of brain network under sedation and anesthesia by different anesthetics in patients with supratentorial glioma and their association with cognition.

NCT ID: NCT06133842 Not yet recruiting - Clinical trials for Postoperative Delirium

CEReBral AutorEgulation in Non-cardiac SuRgery and Relationship to Postoperative DeliriUm State

CERBERUS
Start date: December 2023
Phase:
Study type: Observational

The goal of this observational study is to learn the how to determine the mean arterial pressure(MAP) or blood pressure level to be maintained during non-cardiac surgery for optimal brain health in patients above the age of 60 undergoing major non-cardiac surgery. The main question[s] it aims to answer are: - Is there a way to tailor the blood pressure to be maintained in such patients during surgery for optimal brain health using non-invasive monitors that check the brains electrical activity, the electroencephalogram(EEG) monitor, and the brain's blood oxygen levels, the cerebral oximetry(CO) monitor? - How much does this optimal blood pressure level vary between patients? Participants will be asked to: - Complete a questionnaire at the time they enroll into the study, as well as a daily questionnaire to help determine their level of thinking and brain health. This questionnaire will be administered by a member of the study team. - They will also have an EEG and CO monitoring sticker placed on their foreheads. This will be connected to a monitor that will collect this data just before, during, and after their surgery. The data collected through these monitors will help us with our study goals.

NCT ID: NCT06127901 Not yet recruiting - Clinical trials for Postoperative Delirium

Prevalence and Risk Factors for Postoperative Delirium 48 Hours After Surgery

DELPO
Start date: November 14, 2023
Phase:
Study type: Observational [Patient Registry]

To determine the overall prevalence of postoperative delirium (POI) and its association with different risk factors in order to establish prevention plans to reduce its incidence and/or duration in Spanish hospitals. To this end, patients over 18 years of age who underwent urgent and scheduled surgery requiring hospital admission under any type of anaesthesia during two specific days will be recruited and pre-, intra- and postoperative data will be collected.

NCT ID: NCT06115031 Recruiting - Clinical trials for Postoperative Delirium

Remimazolam vs. Propofol: Impact on Postoperative Delirium in Neurosurgical Patients

Start date: January 29, 2024
Phase: N/A
Study type: Interventional

The investigator aimed to evaluate the incidence of postoperative delirium after remimazolam-based total intravenous anestheisa (TIVA) compared to the propofol-based TIVA in patients undergoing neurosurgery.

NCT ID: NCT06102967 Not yet recruiting - Frailty Clinical Trials

EEG Characteristics and Postoperative Delirium

Start date: November 1, 2023
Phase:
Study type: Observational

The goal of this [type of study: observational study ] is to [compare Energy differences in various bands of intraoperative electroencephalogram in elderly patients with postoperative delirium and non delirium.] in [describe participant population selected 69 patients who underwent laparoscopic radical surgery for colorectal cancer on a selective basis]. The main question[s] it aims to answer are: • [Is there any difference in the spectral range of EEG between POD patients and non POD patients] Participants will [Cognitive.•Postoperative delirium.•Preoperative weakness.]