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Emergence Delirium clinical trials

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NCT ID: NCT06467552 Recruiting - Clinical trials for Postoperative Delirium

Effects of Nutritional Support on Postoperative Delirium

Start date: June 2024
Phase: N/A
Study type: Interventional

This study is a prospective, single-center, randomized controlled trial to compare whether applying nutritional supplementation therapy before and after surgery in elderly patients aged 65 years or older undergoing non-cardiac surgery can reduce the incidence of postoperative delirium.

NCT ID: NCT06466096 Not yet recruiting - Clinical trials for Postoperative Delirium

Correlation Analysis of POD and pNCD in Elderly Patients With Gastrointestinal Neoplasms Based on Rs-fMRI

Start date: June 20, 2024
Phase:
Study type: Observational [Patient Registry]

This is a prospective cohort study to explore the differences of resting-state functional magnetic resonance imaging (fMRI) between elderly gastrointestinal neoplasms patients with postoperative delirium (POD) who either develop or do not develop long-term postoperative neurocognitive disorders (pNCD).

NCT ID: NCT06466083 Not yet recruiting - Clinical trials for Postoperative Delirium

Correlation Analysis of POD and PND in Elderly Spinal Surgery Patients Based on Rs-fMRI

Start date: June 14, 2024
Phase:
Study type: Observational [Patient Registry]

This study is a prospective cohort study to investigate the differences in resting-state functional magnetic resonance imaging (fMRI) between elderly spinal surgery patients with postoperative delirium (POD) who either develop or do not develop long-term postoperative neurocognitive disorders (pNCD).

NCT ID: NCT06459089 Not yet recruiting - Emergence Delirium Clinical Trials

The Effects of Familiar Toy and Parental Presence Combination on Perioperative Pediatric Anxiety

Start date: June 30, 2024
Phase:
Study type: Observational

This study will evaluate the effect of presence of favorite toy and parent during perioperative period on pediatric anxiety and emergence delirium. Half of the patients patients will be accompanied with their ownselected parent and the other half will be accompanied with their favorite toy in addition to their own selected parent.

NCT ID: NCT06445153 Recruiting - Clinical trials for Postoperative Delirium

Digitalized Clinical Decision Support for the Prevention of Postoperative Delirium (POD)

Start date: June 3, 2024
Phase: N/A
Study type: Interventional

The project aims to improve patient safety, reduce barriers to the implementation of current guideline recommendations, reduce workload in clinics, increase efficiency in work processes and close gaps in care.

NCT ID: NCT06443957 Completed - Clinical trials for Postoperative Delirium

The Preventive Effect of Different Doses of Intranasal Insulin on Postoperative Delirium

Start date: July 29, 2023
Phase: N/A
Study type: Interventional

Postoperative delirium is one of the common complications in the older aldults after surgery, which can lead to longer hospita stay,memory loss and reduced quality of life. There is currently no specific treatment. Therefore, it is important to prevent the occurrence of postoperative delirium. This study investigated the effect of intranasal insulin administration on the prevention of postoperative delirium and compared different doses of insulin to find a safe and acceptable method for preventing delirium.

NCT ID: NCT06434948 Not yet recruiting - Clinical trials for Postoperative Delirium

The Effect of Omega 3 Supplementation on Postoperative Delirium in Elderly Patients Undergoing Major Cardiac Surgery

Start date: June 2024
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether giving omega-3 fatty acids prior to and after cardiac bypass surgeries decreases the incidence of postoperative delirium in patients aged 65 and over.

NCT ID: NCT06426953 Recruiting - Diabetes Clinical Trials

Predictive Effect of TGF-β Combined With INS-PI3K-AKT Signaling Pathway Related Proteins (ADNP, MAP6, Pgc-1α) for POD on Diabetes Patients

Start date: May 20, 2024
Phase:
Study type: Observational

To investigate the relationship between POD, TGF-β and INS-PI3K-AKT signaling pathway related proteins (ADNP, MAP6, PGC-1α) in diabetic patients

NCT ID: NCT06423547 Not yet recruiting - Surgery Clinical Trials

Risk Warning Model of Postoperative Delirium and Long-term Cognitive Dysfunction in Elderly Patients

Start date: June 15, 2024
Phase:
Study type: Observational [Patient Registry]

The incidence of postoperative delirium in elderly patients is high, which can lead to long-term postoperative neurocognitive disorders. Its high risk factors are not yet clear. At present, there is a lack of early diagnosis and alarm technology for perioperative neurocognitive disorders, which can not achieve early intervention and effective treatment. By artificial intelligence and autonomously evolutionary neural network algorithm, relying on multi-source clinical big data, we explored the use of Bayesian network to optimize the anesthesia decision-making system in enhanced recovery after surgery, and established risk prediction model for perioperative critical events. It is expected that this method will also help to establish a risk prediction model for postoperative delirium and long-term postoperative neurocognitive disorders. This project plans to collect the perioperative sensitive parameters of anesthesia machine, multi-parameter monitor, EEG monitor,fMRI and HIS system, to explore the evolution process of data characteristics by feature fusion.We also plan to quickly screen key perioperative risk characteristics of postoperative delirium from massive clinical data through feature selection, to explore the high risk factors of long-term postoperative neurocognitive disorders developing from postoperative delirium. Finally, with multi-center intelligent analysis,the risk prediction model of postoperative delirium and long-term postoperative neurocognitive disorders will be constructed.

NCT ID: NCT06421090 Recruiting - Clinical trials for Vagus Nerve Stimulation

Transauricular Vagal Nerve Stimulation Improves Postoperative Delirium in Elderly Patients

Vnstar-IIa
Start date: May 21, 2024
Phase: N/A
Study type: Interventional

To investigate the efficacy and safety of perioperative Transauricular vagal nerve stimulation in improving Postoperative Delirium in elderly patients undergoing elective surgery Lay the groundwork for a Phase III study.