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Clinical Trial Summary

The aim of this study is to prospectively validate the safety and efficiency of management according to the YEARS algorithm to safely rule out clinically suspected PE in patients with active malignancy to be compared with 'standard' management by computed tomography pulmonary angiography (CTPA) alone in a randomized study.


Clinical Trial Description

Recently, the YEARS-algorithm was demonstrated to be a safe and efficient diagnostic strategy for patients with clinically suspected pulmonary embolism (PE). It is recognized that diagnostic algorithms for pulmonary embolism (PE) may not be as effective and safe in patients with malignancy, due to the low specificity of D-dimer test in that setting. A diagnostic algorithm that could safely rule out PE in patients with malignancy without performing computed tomography pulmonary angiography (CTPA) could nonetheless improve patient care. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04657120
Study type Interventional
Source University Hospital, Brest
Contact Emily MARTENS, MD
Phone 71-5298096
Email e.s.l.martens@lumc.nl
Status Recruiting
Phase N/A
Start date June 1, 2019
Completion date May 2024

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