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Apixaban for Treatment of Embolic Stroke of Undetermined Source — ATTICUS  

Embolic Stroke of Undetermined Source Clinical Trial

Official title:
Apixaban for Treatment of Embolic Stroke of Undetermined Source (ATTICUS Randomized Trial)

Clinical Trial Summary

Multicentre (national, Germany), randomized (2x2 factorial), open, parallel group, active controlled, efficacy study (phase III)

Clinical Trial Description

Based on the previous data, ATTICUS is designed as multicentre, national, parallel group, active controlled, phase III randomized (2x2 factorial), clinical trial to demonstrate the superiority of apixaban against the current standard of treatment (acetylsalicylic acid) for the longterm treatment after ESUS. ATTICUS will follow a dynamic treatment protocol implementing conversion from the acetylsalicylic acid arm to the apixaban arm in case of detection of relevant episodes of AF during the course of the study. ATTICUS is designed to test the superiority over acetylsalicylic acid to reduce new ischemic lesion detected by FLAIR/DWI MRI. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02427126
Study type Interventional
Source University Hospital Tuebingen
Contact
Status Completed
Phase Phase 3
Start date December 2015
Completion date September 2021
View Details
See also
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