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Elevated Triglycerides clinical trials

View clinical trials related to Elevated Triglycerides.

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NCT ID: NCT04990817 Completed - Clinical trials for Hypertriglyceridemia

Effects of Replacing Energy From Solid Fats and Added Sugars (SoFAS) With Avocado

Start date: June 18, 2021
Phase: N/A
Study type: Interventional

The objective of this study is to assess the effects of replacing energy from SoFAS with energy from avocado on non-high-density lipoprotein cholesterol (non-HDL-C) and other aspects of the cardiometabolic health profile including fasting lipoprotein lipid and particle concentrations, insulin sensitivity and blood pressure in men and women with elevated triglycerides (TG).

NCT ID: NCT04754373 Completed - Clinical trials for Elevated Triglycerides

A Study to Evaluate the Effect of GFA-918 on Serum Triglyceride Levels in Individuals With Elevated Serum Triglyceride

Start date: July 13, 2018
Phase: Phase 2
Study type: Interventional

In this study, a lipase -sourced from a nonpyrogenic yeast, Candida rugosa, will be investigated to establish optimal TG levels in adults in a 12-week supplementation period. The investigational product provides a lipase formulation that is stable and active in acidic and neutral pH environments, while also fully digesting TGs into free fatty acids and glycerol which is beyond the scope of pancreatic lipase (Schuler et al. 2012). This will be a novel study investigating the effects of C. rugosa lipase on adults with slightly elevated TG levels.

NCT ID: NCT01562782 Completed - Diabetes Clinical Trials

Change of Fructose to Fat in South Asians

Start date: April 2, 2012
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether hepatic de novo lipogenesis (DNL) in response to the ingestion of a mixture of glucose and fructose is greater in South Asians compared to controls (Caucasians).

NCT ID: NCT01562080 Completed - Hyperlipidemia Clinical Trials

Combined Effects of Bioactive Compounds in Lipid Profile

ARM-PLUS-LDL
Start date: January 2012
Phase: Phase 2/Phase 3
Study type: Interventional

The aim of this study is to demonstrate whether, along with dietary recommendations, Armolipid Plus ® can improve the profile of patients with elevated plasma LDL-C acting as a change of lifestyle therapy (TLC) according to the definition of Adult Treatment Panel III (ATP III)

NCT ID: NCT00940966 Completed - Insulin Resistance Clinical Trials

A Pilot Study to Determine the Efficacy of a Low Carbohydrate Diet in Treatment of Adolescents With Metabolic Syndrome

Start date: July 2006
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the effectiveness of two different non-energy restricted controlled carbohydrate programs with the American Diabetes Associations' diet on glycosylated hemoglobin and other diabetes risk factors in obese adolescents with metabolic syndrome, a constellation of symptoms associated with the development of type 2 diabetes and cardiovascular disease.

NCT ID: NCT00535535 Completed - Diabetes Clinical Trials

Fructose-Induced Palmitate Synthesis in Overweight Subjects

Start date: August 2007
Phase: Phase 1
Study type: Interventional

Dietary fructose potently exacerbates the dyslipidemia associated with obesity, insulin resistance and accelerated atherosclerosis. In a randomized crossover outpatient study of 15 overweight adults, we will measure the increase over 4 hours in serum VLDL triglyceride palmitate made by the liver from each single oral dose of fructose (0.5 g/kg), fructose:glucose 1:1 (1 g/kg) or fructose:glucose 1:1 (2 g/kg). Our hypotheses are that the synthesis of palmitate from dietary fructose will be 1) greater when consumed with glucose and 2) show a dose-response. The lipogenic responses will be compared and correlated with markers of carbohydrate and lipid flux measured after fasting and post-fructose. The results will serve as a guide to the development of a new outpatient probe of the de novo lipogenic pathway in subjects who vary in their lipogenic response to oral fructose. These studies should ultimately yield valuable new information about the mechanisms linking dietary carbohydrate to elevated triglycerides, diabetes and cardiovascular disease.