Effect of Repeated Botulinum Toxin Injection on Gait Pattern in Stroke Patients Clinical Trial
Official title:
Improvement of Chronic Stroke Patients Gait Pattern Following Repetitive Multifocal Botulinum Toxin Injection Sessions in Paretic Lower Limb: an Observational Study.
Chronic stroke patients exhibit gait pattern alterations which are mainly due to spasticity
and treated with repetitive multifocal botulinum toxin injection(BTI). Several studies
demonstrated that single BTI-session in a single muscle of paretic lower limb(LL) improved
kinematic gait parameters(GP) but surprisingly none of them assessed the effects of
repetitive multifocal BTI on patient's gait pattern and their duration.
The aim was to evaluate the impact of repetitive multifocal BTI-sessions on GP of chronic
stroke patients. To that end, gait of patients has been compared using 3D-gait analysis
after at least 2 consecutive BTI sessions.
All the patients will be tretaed with BTI . these injections will be performed under electrical stimulation control (~5mA). The dose, the number of site of injection per muscle is at the discretion of the physician according to patients' needs and physicians' routine clinical practice. The dilution the most commonly used will depend on the type of BoNT-A (BOTOX®, XEOMIN® or DYSPORT®) and was 100 U for 2.5ml (BOTOX® and XEOMIN®) or 500 U for 2.5 ml (Dysport®). ;
Time Perspective: Retrospective