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Edema clinical trials

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NCT ID: NCT04700735 Completed - Edema Leg Clinical Trials

Cross Therapy Registry - Edema - US

CTR-Edema-US
Start date: June 22, 2021
Phase:
Study type: Observational [Patient Registry]

The geko™ Cross Therapy Registry - Edema (gekoTM CTR - Edema) study will prospectively and systematically collect clinical data on all device variants used in standard care pathways for edema management allowing for the monitoring of patient outcomes during a follow-up period of up to twelve months.

NCT ID: NCT04683887 Completed - Edema Arm Clinical Trials

Taping to Control Edema in Patients With Forearm Plaster for Wrist Fracture.

Start date: June 25, 2021
Phase: N/A
Study type: Interventional

Wrist fractures are a very common event affecting patients of all ages and are estimated to account for approximately 10% -25% of all fractures. 70-90% of fractures are treated with closed reduction and forearm cast. In 2019, 17.4% of wrist fractured patients treated with a plaster cast at the Orthopedic Emergency Department (OED) of the Local Health Unit ("Azienda Unità Sanitaria Locale", AUSL) of Piacenza had a second access to the OED for edema, pain or "intolerance to the plaster cast ". In literature, there are several studies that demonstrate the effectiveness of adhesive elastic tape for edema control, mostly lymphedema secondary to breast cancer or post-operative edema after knee arthroplasty, although a definitive evidence is still needed. With this trial, the investigators aim to evaluate the tape effectiveness in counteracting hand edema formation in wrist fractured adult patients treated with forearm cast.

NCT ID: NCT04674800 Completed - Clinical trials for Diabetic Macular Edema

Extension Study of MYL-1701P-3001 for Safety and Efficacy

Start date: November 23, 2020
Phase: Phase 3
Study type: Interventional

This Study (AFIL-IJZ-3002) is designed to evaluate the safety, efficacy and immunogenicity of MYL-1701P among a group of participants successfully completing MYL-1701P-3001 study.

NCT ID: NCT04657874 Completed - Postoperative Pain Clinical Trials

Bromelain and Escin in the Reduction of Postoperative Sequelae in Periodontal and Implant Surgery

Start date: December 1, 2020
Phase: N/A
Study type: Interventional

A randomized clinical trial will be performed in parallel, placebo controlled, triple-blind to evaluate the effectiveness of the association Bromelina and Horse-chestnut (titrated in escin) (Noflogo®, Mavenpharma s.r.l., Rome, Italy) in the management of post trauma-surgery following surgery periodontal and implant surgery.

NCT ID: NCT04635800 Completed - Clinical trials for Diabetic Macular Edema

A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of IVT MHU650 in Macular Edema Patients

Start date: December 10, 2020
Phase: Phase 1
Study type: Interventional

This was an open-label, multi-center, FIH study with a single ascending dose (SAD) design that assessed the safety, tolerability and pharmacokinetics (PK) of a single IVT dose of MHU650 in up to 24 participants with macular edema.

NCT ID: NCT04619303 Completed - Clinical trials for Diabetic Retinopathy

Intravitreal Dexamethasone vs Bevacizumab in Aboriginal People With DMO

OASIS
Start date: February 7, 2017
Phase: Phase 4
Study type: Interventional

DMO is the most common cause of visual loss in people with diabetes. Regular injections of bevacizumab (Avastin) given as frequently as every month remain the current standard of care for centre-involving DMO; however, this regimen is impractical for many Aboriginal patients. Using Ozurdex implants every 3-6 months could be as effective as the currently used Avastin injections. In order to address this real-world problem, this study seeks to investigate whether it is possible to safely use a long-acting steroid preparation such as the dexamethasone IVT implant (Ozurdex) to manage DMO in Aboriginal patients living in Western Australia.

NCT ID: NCT04597918 Completed - Clinical trials for Diabetic Macular Edema

A Study to Investigate Aqueous Humor and Multimodal Imaging Biomarkers in Treatment-Naïve Participants With Diabetic Macular Edema Treated With Faricimab

ALTIMETER
Start date: November 25, 2020
Phase: Phase 2
Study type: Interventional

This is an exploratory, prospective, multicenter, open-label, single-arm, interventional, Phase IIb study designed to explore the associations over time between clinical assessments, multimodal imaging assessments, aqueous humor (AH) biomarker patterns, and genetic polymorphisms in participants with diabetic macular edema (DME) who are treated with faricimab.

NCT ID: NCT04595448 Completed - Heart Failure Clinical Trials

Lymphatic Function in Patients With Secondary Tricuspid Valve Regurgitation

LYMTRIVA
Start date: September 15, 2020
Phase:
Study type: Observational

The study will examine the lymphatic functional and morphological status in patients with moderate tricuspid valve regurgitation compared to healthy age and gender-matched controls. The study will use t2 weighted MRI, Near-infrared fluorescence imaging, and plethysmography to examine the above-mentioned question.

NCT ID: NCT04593693 Completed - Diabetic Foot Ulcer Clinical Trials

A Dual-center Study Evaluating Clinical Acceptance of a NPWT Wound Care System

Start date: December 10, 2020
Phase: N/A
Study type: Interventional

The purpose of this study is to determine if use of the Medela Invia Motion NPWT system supports acceptable progress towards the goal of therapy when treating patients with a variety of wound types during the evaluation period.

NCT ID: NCT04592419 Completed - Macular Edema Clinical Trials

A Study to Evaluate the Efficacy, Durability, and Safety of KSI-301 Compared to Aflibercept in Patients With Macular Edema Due to Retinal Vein Occlusion (RVO)

BEACON
Start date: September 25, 2020
Phase: Phase 3
Study type: Interventional

This Phase 3 study will evaluate the efficacy, durability, and safety of KSI-301 compared to aflibercept, in participants with macular edema due to treatment-naïve branch (BRVO) or central retinal vein occlusion (CRVO).