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E.Coli Infections clinical trials

View clinical trials related to E.Coli Infections.

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NCT ID: NCT05277350 Completed - Clinical trials for Bloodstream Infection

A Study Investigating the Safety, Recovery, and Pharmacodynamics of Multiple Oral Administrations of SNIPR001 in Healthy Subjects

Start date: March 24, 2022
Phase: Phase 1
Study type: Interventional

This is a Phase 1, randomized, double-blind, placebo-controlled, multiple dose, dose escalation study in healthy participants, investigating the safety, tolerability, recovery, and PD of multiple oral administrations of SNIPR001.

NCT ID: NCT04087681 Completed - E.Coli Infections Clinical Trials

Study to Collect Information About Invasive Disease Caused by Extraintestinal Pathogenic Escherichia Coli (EXPECT-1)

EXPECT-1
Start date: September 28, 2019
Phase:
Study type: Observational

The purpose of this study is to collect information from study participants who develop an invasive disease caused by Extraintestinal pathogenic E. coli (ExPEC) during a period of 12 months. This information will be used to support the development of a new vaccine to prevent ExPEC infections.

NCT ID: NCT03021434 Completed - Diarrhea Clinical Trials

Trial of Low-cost Microbiological Water Test Kits

Start date: January 2017
Phase: N/A
Study type: Interventional

The present study is a cluster randomized control trial of low-cost microbiological water test kits in rural and peri-urban communities in the Kanpur region of Uttar Pradesh, India.

NCT ID: NCT02289794 Completed - E.Coli Infections Clinical Trials

Vaccine Against Escherichia Coli Infection

Start date: January 2014
Phase: Phase 1
Study type: Interventional

This Phase I multi-center placebo controlled study is conducted in healthy women with a history of recurrent urinary tract infections (UTI) aged between 18 and 70 years.

NCT ID: NCT00877708 Completed - E Coli Infections Clinical Trials

Clinical and Microbiologic Characteristics of Cephalosporin-Resistant E. Coli-PITT Protocol

Start date: March 2009
Phase:
Study type: Observational

The purpose of this study is to review patients with E. coli infections at UPMC from September 1, 2008 to August 31, 2010 to determine if these infections have arisen in the community rather than in hospitals or nursing homes and determine their clinical outcomes. The specific aims of this study are to: 1. Review whether cephalosporin-resistant E. coli infections are hospital-acquired, healthcare-associated or community-associated. 2. Determine the clinical outcome of the patients according to the antibiotics given.

NCT ID: NCT00363220 Completed - Infection Clinical Trials

Community - Associated Extended-spectrum Beta-lactamases (ESBL)

Start date: August 2006
Phase: N/A
Study type: Observational

The purpose of this study is to review patients with E. coli infections at the University of Pittsburgh Medical Center (UPMC) from September 1, 2006 to August 31, 2007 to determine if these infections have arisen in the community rather than in hospitals or nursing homes. The occurrence of such resistant isolates could be devastating if they were associated with bloodstream infection, such as sometimes accompanies a urinary tract infection, since antibiotic resistant E. coli is not suspected in isolates coming from the community. Therefore, the aims of this study are to: 1. Review whether extended-spectrum beta-lactamase (ESBL)-producing organisms (E. coli, Klebsiella species and Proteus species) are hospital-acquired, healthcare-associated, or community-associated. 2. Investigate the prevalence of ESBL-positive E. coli in foodstuffs (beef, poultry, turkey, and pork), as a potential source for ESBL producers in the community. 3. Compare the clonal relationship of the genome and resistance plasmids carried by the ESBL-producing isolates (healthcare-associated, community-associated, and of animal origin) and study the associations of ESBL-mediated resistance with resistance to other classes of antimicrobials.