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Twice Weekly Steroids and Exercise as Therapy for DMD

Duchenne Muscular Dystrophy (DMD) Clinical Trial

Official title:
Impact and Interplay of Corticosteroid Regimen and Exercise Training on DMD Muscle Function

Clinical Trial Summary

The study team will determine the potential of low dose twice weekly prednisone and whether exercise training can synergize to delay disease progression and improve muscle strength/physical function in boys with Duchenne muscular dystrophy (DMD). Current standard of care (daily prednisone) is associated with adverse side effects. Evidence from DMD mouse models suggest that weekly dosing provides same efficacy without side effects. Appropriate exercise may also benefit but this area has not been adequately explored.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04322357
Study type Interventional
Source University of Florida
Contact Tanja Taivassalo, PhD
Phone (352) 294-8748
Email ttaivassalo@ufl.edu
Status Recruiting
Phase Phase 2
Start date July 30, 2020
Completion date October 7, 2025
View Details
See also
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