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Clinical Trial Summary

The primary purpose of this study is to evaluate the safety, tolerability, and dystrophin protein levels in muscle tissue following multiple intravenous (IV) doses of DYNE-251 in participants with Duchenne muscular dystrophy (DMD) amenable to exon 51 skipping. The study consists of 3 periods: a multiple-ascending dose (MAD) / placebo-controlled period (24 weeks), an open-label period (24 weeks) and a long-term extension period (96 weeks).


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05524883
Study type Interventional
Source Dyne Therapeutics
Contact Dyne Clinical Trials
Phone +1-781-317-1919
Email clinicaltrials@dyne-tx.com
Status Recruiting
Phase Phase 1/Phase 2
Start date August 12, 2022
Completion date November 2026

See also
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