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Dry Mouth clinical trials

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NCT ID: NCT03649789 Completed - Clinical trials for Periodontal Diseases

Periodontal Outcomes After Sanative Therapy

Start date: August 1, 2018
Phase:
Study type: Observational

Salivary gland hypofunction, or dry mouth, is a damaging oral condition that affects salivary gland production. Absence of saliva causes bad breath, dental decay, increased plaque accumulation, dry lips, mouth sores, and the inability to retain dentures or removable protheses. This study will determine if patients with dry mouth have different periodontal health than patients without dry mouth. Additionally, this study will examine if patients who have their periodontal maintenance appointments solely at a periodontal speciality clinic have different periodontal health than patients who alternate their appointments between a specialty office and their general dental office.

NCT ID: NCT03281486 Completed - Xerostomia Clinical Trials

"Hyaluronan" Formulation for Type 2 Diabetic Patients With Dry Mouth

Start date: January 28, 2018
Phase: N/A
Study type: Interventional

An increased incidence of dental caries in association with poorly controlled diabetes has also been reported, Xerostomia (dry mouth) has been reported to be a common complaint of patients with diabetes, Without adequate saliva production, both hard and soft tissues of the mouth can be severely damaged and become more susceptible to infections. This 9 week, cross-over group, randomized, single center, study will evaluate the efficacy of HA formulation in alleviating dry mouth in type 2 diabetic patients.

NCT ID: NCT03215251 Completed - Dry Mouth Clinical Trials

Effectiveness of an Intervention Bundle on Thirst Intensity and Dry Mouth Among Patients in ICUs

Start date: November 2015
Phase: N/A
Study type: Interventional

The study evaluates the effectiveness of an Intervention Bundle on Thirst Intensity and Dry Mouth among Patients admitted in ICUs. Patients were randomized into two groups - Experimental and Control group. Experimental group received intervention Bundle whereas control group didn't receive any intervention. Usual care was continued in both the groups.

NCT ID: NCT03035825 Completed - Dry Mouth Clinical Trials

Efficacy of Oral Moisturizing Jelly on Oral Health and Nutrition in Post-radiotherapy Head and Neck Cancer Patients

Start date: March 1, 2017
Phase: N/A
Study type: Interventional

This randomized control trial aims to investigate the efficacy of oral moisturizing jelly in head and neck cancer patients with xerostomia.

NCT ID: NCT01903122 Completed - Dry Mouth Clinical Trials

Crossover Bioequivalence Study of Cevimeline 30 mg Capsules Under Fasted Conditions

Start date: February 2009
Phase: Early Phase 1
Study type: Interventional

The objective of this study was to prove the bioequivalence of Roxane Laboratories' Cevimeline 30 mg under fasted conditions

NCT ID: NCT01903109 Completed - Dry Mouth Clinical Trials

Crossover Bioequivalence Study of Cevimeline 30 mg Capsules Under Fed Conditions

Start date: February 2009
Phase: Early Phase 1
Study type: Interventional

The objective of this study was to prove the bioequivalence of Roxane Laboratories' Cevimeline 30 mg under fed conditions

NCT ID: NCT01885065 Completed - Cancer Clinical Trials

Efficacy of Novel Edible Gel-based Artificial Saliva in Cancer Patients

Start date: July 2012
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether continuous use of edible, gel-based artificial saliva in cancer patients with dry mouth problems will reduce signs and symptoms of dry mouth and improve quality of patients' saliva.

NCT ID: NCT01737307 Completed - Infection Clinical Trials

Effect of Fluoride Varnish and CPP-ACP on Oral and Salivary Symptoms During Chemotherapy

Start date: March 2011
Phase: Phase 2
Study type: Interventional

The purpose of this study was to investigate the effect of Fluoride varnish and Casein Phospho-Peptide Amorphous Calcium Phosphate (CPP-ACP) containing paste on oral symptoms and salivary characteristics in patients under chemotherapy.

NCT ID: NCT01690052 Completed - Dry Mouth Clinical Trials

Efficacy of Cevimeline Versus Pilocarpine in the Secretion of Saliva

Start date: January 2009
Phase: N/A
Study type: Interventional

The main objectives were: 1) To determine the efficacy of both cevimeline and pilocarpine in the secretion of saliva in patients with xerostomia, and 2) To compare the side-effects between the treatment for xerostomia with cevimeline and with pilocarpine.

NCT ID: NCT01647737 Completed - Xerostomia Clinical Trials

Green Tea Lozenges for the Management of Dry Mouth

Start date: March 2011
Phase: Phase 1/Phase 2
Study type: Interventional

The goal of this proposal is to investigate the effectiveness of a Medical College of Georgia patent pending formulation of natural plant extracts on patients with xerostomia. The major component of this formulation is green tea extract with a defined composition of polyphenols. Epidemiological studies suggest that phytochemicals in green tea possess beneficial effects on autoimmune and inflammatory diseases. Thus far, there is little evidence to indicate any marked and direct immunomodulatory effect of green tea on T or B lymphocytes. However, there is considerable evidence for green tea polyphenols (GTPs), major phytochemicals found in green tea extract, having properties consistent with effects on cells of tissues that would be protective towards local inflammation.