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Dry Eye Syndromes clinical trials

View clinical trials related to Dry Eye Syndromes.

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NCT ID: NCT02511379 Terminated - Dry Eye Clinical Trials

Clinical Evaluation of Systane® Balance in Dry Eye Subjects

Start date: November 26, 2015
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of Systane® Balance following 90 days of QID (4 times/day) dosing among Indian subjects with dry eye.

NCT ID: NCT02503176 Terminated - Clinical trials for Dry Eye With Sjögren's Syndrome

An Extension Study of KCT-0809 in Dry Eye Patients With Sjögren's Syndrome

Start date: n/a
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate of the long-term safety and efficacy of KCT-0809 in dry eye patients with Sjögren's syndrome.

NCT ID: NCT02199964 Terminated - Dry Eye Clinical Trials

The Effects of Cyclosporin A in a Low Humidity Environment, on the Ocular Surface

CsA
Start date: March 2014
Phase: N/A
Study type: Interventional

This study will test that hypothesis that topical administration of the FDA approved immunomodulatory agent cyclosporin A emulsion will minimize irritation and ocular surface disease that results from a short term low humidity environmental stress

NCT ID: NCT02193490 Terminated - Dry Eye Clinical Trials

DNase Treatment for Dry Eyes

Start date: July 2014
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to evaluate the tolerability and preliminary efficacy of DNase eye drops in patients with Sjogren's and Non-Sjogren Dry Eye Disease.

NCT ID: NCT02031172 Terminated - Dry Eye Syndromes Clinical Trials

Effects of Sustained Reading on the Ocular Surface

Start date: March 2014
Phase: N/A
Study type: Observational

This research is being done to to see if changes in visual reading function correlate with changes in optical and retinal image quality. We hypothesize that changes and deterioration in tear film quality and dynamics may have a negative effect on reading function. People with or without dry eye syndrome may enroll.

NCT ID: NCT02013791 Terminated - Dry Eye Syndromes Clinical Trials

Phase 2 Study of a New Ophthalmic Formulation of Cyclosporine (Restasis® X) in Patients With Dry Eye Disease

Start date: April 29, 2014
Phase: Phase 2
Study type: Interventional

This study will evaluate a new ophthalmic formulation of cyclosporine (Restasis® X) in patients with moderate to severe dry eye disease in two stages. Up to 3 doses will be studied in Stage 2 based on results from Stage 1. No patients participating in Stage 1 will participate in Stage 2 of this study. This study was terminated and Stage 2 of the study was cancelled.

NCT ID: NCT01450787 Terminated - Dry Eyes Clinical Trials

Prevalence of Dry Eyes in Diabetics Compared to Non Diabetics

Start date: January 2012
Phase: N/A
Study type: Observational

The purpose is to compare the prevalence of dry eyes in diabetics and non diabetics. This might help identify a group of patients at greater risk for dry eye complications. Diabetics have been shown to have poor ocular surface healing and might benefit from dry eye therapy earlier if they are shown to be at greater risk for dry eyes.

NCT ID: NCT01228929 Terminated - Healthy Clinical Trials

Non-invasive Ocular Surface Measurements Before and After Interventions

Start date: July 2010
Phase: N/A
Study type: Interventional

Objectively evaluate the ocular surface (pre-corneal tear film) of individuals prior to and after an intervention (such as a dry eye treatment, environmental change, artificial tear use, or contact lens wear) in a controlled-environmental chamber, over time using non-contact instruments.

NCT ID: NCT01213342 Terminated - Clinical trials for Keratoconjunctivitis Sicca

Omega-3 Fatty Acid Supplements and Dry Eye

Start date: May 2010
Phase: N/A
Study type: Interventional

Omega-3 fatty acids have been associated with a decline in inflammation. As dry eye disease is associated with inflammation of the ocular surface (DEWS report, Ocular Surface, 2007), the investigators hypothesize that the omega-3 fatty acid supplements used in this study will help to improve dry eye signs, such as eye surface irritation (staining) and tear film osmolarity, which is an overall measure of tear film stability and dry eye status. Further, the investigators hypothesize that dry eye symptoms, the end result of dry eye disease, such as discomfort and burning, will also improve with supplementation.