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Dry Eye Syndromes clinical trials

View clinical trials related to Dry Eye Syndromes.

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NCT ID: NCT06404541 Active, not recruiting - Dry Eye Syndromes Clinical Trials

A Comparative Study Between Preservative With Benzalkonium Chloride vs Preservative Free Eye Drops on the Ocular Surface

Start date: January 10, 2024
Phase: Phase 4
Study type: Interventional

study the effect of different concentrations of benzalkonium chloride on the ocular surface of non-dry-eyed patients post cataract surgery.

NCT ID: NCT06390644 Active, not recruiting - Dry Eye Clinical Trials

Effect of Periorbital Massage on Dry Eye Disease

Start date: October 1, 2023
Phase: N/A
Study type: Interventional

This randomized controlled trial aims to investigate the efficacy of periorbital massage therapy in alleviating symptoms and improving clinical outcomes in patients diagnosed with dry eye disease.

NCT ID: NCT06208384 Active, not recruiting - Dry Eye Disease Clinical Trials

Topical Statin Eye Drop in the Management of the Dry Eye

Start date: January 4, 2024
Phase: Phase 1/Phase 2
Study type: Interventional

In the first stage, to evaluate the safety of the topical medication produced by Sina Pharmaceuticals, this medication is experimentally tested on 10 volunteer patients. If no side effects occur, eligible patients are enrolled in the study after examination by a specialist. The second stage is a randomized, double-blind clinical trial, during which selected patients are randomly assigned to the control and intervention groups. For patients in the intervention group, in addition to standard treatment, including eyelid hygiene and the use of artificial tears, a topical drop of Atorvastatin (50 microM) will be administered, one drop eight times a day in both eyes. In the control group, a placebo will be used in the same manner. The patients will be unaware of their assigned group. Clinical examinations, including Schirmer's test, tear breakup time, fluorescein staining, and completion of the dry eye syndrome questionnaire and dry eye questionnaire, will be conducted before and after the intervention to assess the level of eye dryness.

NCT ID: NCT05938985 Active, not recruiting - Dry Eye Clinical Trials

Croatian Version of the Ocular Surface Disease Index Questionnaire (OSDI)

Cro-OSDI
Start date: June 12, 2023
Phase:
Study type: Observational

Ocular Surface Disease Index (OSDI) Questionnaire is an important tool for the diagnosis of dry eye disease. Croatian version is yet not available. With a permission of AbbVie company investigators want to make a Croatian version of the Ocular Surface Disease Index Questionnaire (Cro-OSDI).

NCT ID: NCT05896670 Active, not recruiting - Dry Eye Disease Clinical Trials

Safety and Efficacy of Licaminlimab Ophthalmic Suspension for the Treatment of Dry Eye Disease

RELIEF
Start date: November 29, 2023
Phase: Phase 2
Study type: Interventional

The goal of this clinical trial is to learn about licaminlimab (OCS-02) in the treatment of dry eye disease. The main question it aims to answer is if licaminlimab ophthalmic suspension is more effective than vehicle in treating signs of dry eye disease.

NCT ID: NCT05814757 Active, not recruiting - Dry Eye Syndromes Clinical Trials

OTX-DED for the Short-term Treatment of the Symptoms of Dry Eye Disease (DED)

Start date: May 11, 2023
Phase: Phase 2
Study type: Interventional

To assess the efficacy and safety of OTX-DED for the short-term treatment of the symptoms of DED

NCT ID: NCT05763940 Active, not recruiting - Clinical trials for Age-Related Macular Degeneration

Efficacy of OmegaBoost to Increase Omega-3 Levels in Healthy Individuals

Start date: May 25, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to determine increases in the Omega Index test indicating optimal Omega-3s particularly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) levels for overall systemic benefits including healthy cardiovascular health and cholesterol levels as shown in the OmegaIndex (OmegaQuant) research.

NCT ID: NCT05618730 Active, not recruiting - Dry Eye Clinical Trials

Safety, Tolerability, Plug Retention and Preliminary Efficacy of Tacrolimus-loaded Punctal Plug in Patients With Moderate to Severe Dry Eye Disease - Cohort B

Start date: September 29, 2022
Phase: Phase 1
Study type: Interventional

The purpose of this interventional study is to assess safety, patient tolerability, plug retention rate, and preliminary efficacy in improving the symptoms of Dry Eye Disease (DED) of EXP-TC tacrolimus releasing punctal plug. The main questions it aims to answer are: 1. The safety of using EXP-TC plug following all study adverse events 2. The number of patients with Adverse Events related to the us of EXP-LP plug 3. The number of patients discontinuing the study due to plug discomfort 4. The total patients with plugs remained during the 3-months study duration from plug insertion 5. Exploratory: change from baseline in the study eye to follow-up visits in various Dryness clinical measurements. The change of measurements from baseline will also be compared between the study and fellow control eye (receiving artificial tears only, 0.15% sodium hyaluronate).

NCT ID: NCT05467293 Active, not recruiting - Dry Eye Clinical Trials

Phase 2, Multi-center, Randomized, Double- Masked and Placebo-Controlled Study of YP-P10 Ophthalmic Solution Compared to Placebo in Subjects With Dry Eye (ICECAP 1)

Start date: June 27, 2022
Phase: Phase 2
Study type: Interventional

The objective of this study is to compare the safety and efficacy of YP-P10 Ophthalmic Solution to placebo for the treatment of the signs and symptoms of dry eye.

NCT ID: NCT05096546 Active, not recruiting - Dry Eye Syndromes Clinical Trials

The Proportion of Patients Diagnosed With Dry Eye by the Asia Dry Eye Society (ADES) Criteria in Taiwan (DECS-TW)

DECS-TW
Start date: October 21, 2021
Phase:
Study type: Observational

The study aims to determine the proportion of patients diagnosed with dry eye by the Asia Dry Eye Society (ADES) criteria, among patients diagnosed with dry eye disease under current hospital-based practice in Taiwan.