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Dry Eye Syndromes clinical trials

View clinical trials related to Dry Eye Syndromes.

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NCT ID: NCT04454983 Completed - Dry Eye Clinical Trials

Lipiflow vs iLux Patient Acceptance and Comfort Study

Start date: January 11, 2020
Phase: N/A
Study type: Interventional

This study was designed to compare patient acceptance, comfort, and preference between two meibomian gland clearing devices (Lipiflow vs, iLux). Primary Objective was to compare patient comfort as assessed by Likert-style scale questionnaire following each bilateral procedure. Secondary Objective was to compare overall experience and treatment preference as assessed by Likert-style questionnaire following each bilateral procedure. Both devices are exempt from IDE regulations [21 CFR 812.2(c)].

NCT ID: NCT04454281 Completed - Neuropathic Pain Clinical Trials

Topical Naloxone to Diagnose Ocular Pain

Start date: October 1, 2020
Phase: Phase 1
Study type: Interventional

Chronic ocular neuropathic pain may be misdiagnosed as dry eye disease. Our study aims to identify a population with previous monocular trauma and dry eye symptoms and differentiate neuropathic from dry eye pain using topical corneal naloxone hydrochloride.

NCT ID: NCT04426240 Completed - Dry Eye Syndromes Clinical Trials

The Effect of Cyclosporin Before Cataract Surgery

Start date: August 3, 2020
Phase: Phase 4
Study type: Interventional

To evaluate the effect of cyclosporine eye drop before cataract surgery for the prevention of post cataract surgery dry eye syndrome.

NCT ID: NCT04421300 Completed - Dry Eye Clinical Trials

A Randomized Study of Smile Exercise for Dry Eye

Start date: July 2, 2020
Phase: N/A
Study type: Interventional

The objective of the study is to evaluate the effectiveness of laughter therapy in relieving the symptoms of dry eye disease.

NCT ID: NCT04413279 Completed - Dry Eye Syndromes Clinical Trials

Lipiflow Treatment Alone vs. Lipiflow + Dextenza Treatment for Dry Eye Disease

Start date: August 1, 2020
Phase: Phase 4
Study type: Interventional

To evaluate the benefit of treatment with a physician administered intracanalicular dexamethasone insert in evaporative dry eye disease (DED) patients with meibomian gland disfunction (MGD) and underlying inflammation undergoing LipiFlow Thermal Pulsation.

NCT ID: NCT04393441 Completed - Clinical trials for Dry Eye Disease (DED)

Efficacy and Safety of a New Artificial Tear Formulation Compared With Systane Ultra Multidose in Participants With Dry Eye Disease

Start date: June 29, 2020
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare the efficacy and safety of a new artificial tear formulation (011516X) with Systane® Ultra Multidose for 90 days in participants with Dry Eye Disease (DED).

NCT ID: NCT04391894 Completed - Dry Eye Clinical Trials

A Study to Assess the Safety and Efficacy of ECF843 vs Vehicle in Subjects With Dry Eye Disease

Start date: October 6, 2020
Phase: Phase 2
Study type: Interventional

The study was planned to be conducted in 2 parts: Part 1 to determine the efficacy and safety of ECF843 vs vehicle, followed by Part 2 with additional exploratory assessments of ECF843 vs Vehicle. Both parts of the study included a double-masked study design, with randomization stratified for subjects with Sjogren's Syndrome.

NCT ID: NCT04384991 Completed - Dry Eye Syndromes Clinical Trials

HU007 Eye Drops in Patients With Dry Eye Syndrome

Start date: May 3, 2019
Phase: Phase 3
Study type: Interventional

This study is a multicenter, randomized, double blind, Restasis-controlled non-inferiority, Phase III Study to evaluate the efficacy and safety of HU007 eye drops in patients With dry eye syndrome

NCT ID: NCT04362670 Completed - Dry Eye Disease Clinical Trials

Study to Evaluate the Safety, Tolerability, and Efficacy of OTX-CSI in Subjects With Dry Eye Disease.

Start date: April 23, 2020
Phase: Phase 1/Phase 2
Study type: Interventional

To assess the safety, tolerability and efficacy of a single dose of OTX-CSI, a sustained release cyclosporine drug product, in subjects with dry eye disease.

NCT ID: NCT04357795 Completed - Dry Eye Disease Clinical Trials

Effect of Cequaâ„¢ in Subjects With Dry Eye Disease

Start date: June 29, 2020
Phase: Phase 4
Study type: Interventional

This is a Phase 4, multicenter, single arm, 12 week study in subjects with dry eye disease, which is inadequately controlled by cyclosporine 0.05% ophthalmic emulsion.