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Mono Antiplatelet and Colchicine Therapy — MACT  

Acute Coronary Syndrome Clinical Trial

Official title:
Aspirin-free Therapy After Successful Percutaneous Coronary Intervention for Acute Coronary Syndrome: the MACT (Mono Antiplatelet and Colchicine Therapy) Pilot Study

Clinical Trial Summary

The purpose of this study is to evaluate the efficacy and safety of aspirin-free, P2Y12 inhibitor single antiplatelet and colchicine treatment in patients with acute coronary syndrome treated with drug-eluting stents.

Clinical Trial Description

After successful drug-eluting stent implantation for acute coronary syndrome, screening for study subject enrollment is performed. For those who submitted written informed consent, aspirin is stopped the day after the intervention, and colchicine 0.6mg once daily is started. The P2Y12 inhibitor, prasugrel or ticagrelor, for single antiplatelet therapy remains. For the duration of hospital stay, platelet reactivity using VerifyNow test and C-reactive protein are measured. Aspirin may be restarted at the discretion of the investigator based on results of the platelet function test. C-reactive protein is remeasured 30 days after the intervention. Clinical follow-up is performed 30 days and 90 days after the intervention. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04949516
Study type Interventional
Source Wonkwang University Hospital
Contact
Status Completed
Phase Phase 4
Start date June 15, 2021
Completion date December 31, 2022
View Details
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