Anomalies of Nocturnal Gaz Exchanges in Patients With Down Syndrome

Status Completed

Clinical Trial Summary

Recently, retrospective studies have shown that Down Syndrome children have a higher CO2 (carbone dioxide) sleep pressure than the general pediatric population. This increase does not seem to be always related to sleep apnea. The Investigators wish to confirm these results prospectively. The investigators hypothesize that this alveolar hypoventilation may be due to ventilatory control disorders caused by dysautonomia, but also to a decrease in the strength of the respiratory muscles within the framework of the global muscular hypotonia described in children with Down syndrome. .

Clinical Trial Description

47 Down syndrome patients age from 4 to 16 will be included. They will perform a medical visit at J0, then a measurement of gaz nocturnal exchanges at home within 1 month ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03903666
Study type	Interventional
Source	Institut Jerome Lejeune
Contact
Status	Completed
Phase	N/A
Start date	October 14, 2019
Completion date	May 23, 2022

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