A Study of RG1662 in Individuals With Down Syndrome

Status Completed

Clinical Trial Summary

This multi-center, randomized double-blind, placebo-controlled study will assess the safety and tolerability of RG1662 in individuals with Down Syndrome. Eligible subjects will be randomized in cohorts to receive either multiple oral doses of RG1662 or placebo. Anticipated time on study treatment is 38 days.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Safety Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01436955
Study type	Interventional
Source	Hoffmann-La Roche
Contact
Status	Completed
Phase	Phase 1
Start date	November 2011
Completion date	September 2013

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT04854122` - Blood Flow Regulation in Individuals With Down Syndrome - Training Study	N/A
Completed	`NCT04020302` - Self-Monitoring Shopping Intervention	N/A
Recruiting	`NCT01950624` - DS-Connect {TM}: The Down Syndrome Registry
Completed	`NCT04751136` - the Effect of Cerebrolysin on Physical and Mental Functions of Down Syndrome	Phase 2
Completed	`NCT04767412` - Inspiratory Muscle Training and Physical Fitness in Children With Down Syndrome Randomized Control Trial	N/A
Not yet recruiting	`NCT04037579` - Protocol for a Non-randomized Survey in Down Syndrome People Who Practice Sports. Self and Observers´ Perception.
Completed	`NCT04536506` - Bobath and Vojta Therapy for DS	N/A
Completed	`NCT02882698` - Performance Analysis in Down Syndrome on Mobile Phone	N/A
Completed	`NCT01791725` - A 4-Week Safety Study of Oral ELND005 in Young Adults With Down Syndrome Without Dementia	Phase 2
Unknown status	`NCT01975545` - Fluor Varnish With Silver Nanoparticles for Dental Remineralization in Patients With Trisomy 21	Phase 2
Completed	`NCT01808508` - Obstructive Sleep Apnea and Neurocognitive and Cardiovascular Function in Children With Down Syndrome	N/A
Terminated	`NCT00754013` - Evaluating The Efficacy And Safety Of Donepezil Hydrochloride (Aricept) In The Treatment Of The Cognitive Dysfunction Exhibited By Children With Down Syndrome, Aged 6 To 10	Phase 3
Terminated	`NCT00754052` - Evaluating The Efficacy And Safety Of Donepezil Hydrochloride (Aricept) In The Treatment Of The Cognitive Dysfunction Exhibited By Children With Down Syndrome, Aged 11 To 17	Phase 3
Completed	`NCT01256112` - Parent Supported Weight Reduction in Down Syndrome	N/A
Completed	`NCT01313325` - Hippotherapy to Improve the Balance of Children With Movement Disorders	N/A
Completed	`NCT01594346` - Multicenter Vitamin E Trial in Aging Persons With Down Syndrome	Phase 3
Completed	`NCT05343468` - Life Skills Improved in Children With Down Syndrome After Using Assistive Technology	N/A
Suspended	`NCT05755464` - Evaluation of Patients With Down Syndrome Compliance to Dental Therapy
Recruiting	`NCT04022460` - Using Personal Mobile Technology to Identify Obstructive Sleep Apnea in Children With Down Syndrome (UPLOAD)
Completed	`NCT04818437` - Effect of Core Stability Exercises and Balance Training in Postural Control Among Down Syndrome	N/A