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Diverticulitis clinical trials

View clinical trials related to Diverticulitis.

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NCT ID: NCT03443011 Completed - Diverticulitis Clinical Trials

Diagnostics in Diverticulitis (DIDit)

Start date: January 19, 2017
Phase: N/A
Study type: Interventional

This study focuses on if low dose CT without intravenous contrast has a high enough specificity and sensitivity for acute diverticulitis that it can be used as the primary diagnostic method instead of a full dose CT with intravenous contrast which is the standard method in Sweden.

NCT ID: NCT03337984 Completed - Diverticulitis Clinical Trials

Damage Control Surgery in the Treatment of Complicated Diverticulitis

DACSCOD
Start date: September 1, 2017
Phase:
Study type: Observational [Patient Registry]

To evaluate the use of damage control surgery by performing bowel resection and laparostomy in the treatment of Hinchey III or IV diverticulitis.

NCT ID: NCT03332550 Completed - Clinical trials for Perforated Diverticulitis

A National Study of Clinical Results After Emergency Operation for Perforated Diverticulitis

LapLav
Start date: April 18, 2018
Phase:
Study type: Observational

The aim of this study is to evaluate clinical results and effect on health and well-being in patients operated for perforated diverticulitis with purulent peritonitis by laparoscopic lavage in Sweden when used outside of prospective studies/trials and in comparison with the traditional treatment, i.e. colon resection with or without stoma formation. A secondary aim is to evaluate the outcome after fecal peritonitis. The hypothesis is that laparoscopic lavage as treatment for perforated diverticulitis with purulent peritonitis is safe, efficient and cost saving, when used in routine health care.

NCT ID: NCT03325829 Active, not recruiting - Diverticulitis Clinical Trials

Registro Malattia Diverticolare (Registry of Diverticular Disease)

REMAD
Start date: April 2015
Phase: N/A
Study type: Observational [Patient Registry]

To determine the clinical characteristics and risk factors for the onset of diverticular disease and its complications in the Italian population.

NCT ID: NCT03316677 Not yet recruiting - ColoRectal Cancer Clinical Trials

Intraoperative Testing of Colorectal Anastomosis - Air or Water (Methylene Blue)?

ITCORA
Start date: November 1, 2017
Phase: N/A
Study type: Interventional

A leak from a colorectal anastomosis is a post-operative complication surgeons fear the most, following colonic resection. Over the years, there have been multiple suggestions for intraoperative tests for the integrity of the colorectal anastomosis. Two of the most common tests that are performed routinely are: 1. Air tight leak test - filling the pelvis with saline and insufflating air trans anal - looking for air bubbles in the saline filled pelvis. 2. Injecting diluted dye (methylene blue) trans anal, and looking for blue dye stains on gauze pads covering the outer side of anastomosis. The aim of the study is to compare the two methods, and to assess if there is a superior method. A secondary aim is to establish standards to perform the test, mainly to assess the appropriate pressure to apply on the anastomosis. In this prospective study patients scheduled to undergo colonic resection of their distal part of the colon/ rectum with colorectal anastomosis, will have both testing methods performed sequentially and will be followed post-operative to assess the yield and sensitivity of the testing methods.

NCT ID: NCT03279588 Completed - Abdominal Pain Clinical Trials

Diagnostic Accuracy of Bedside Ultrasound in Suspected Acute Diverticulitis

Start date: May 20, 2017
Phase:
Study type: Observational

Colonic diverticulitis is a common clinical condition in patients presenting to the Emergency Department (ED) with abdominal pain. The diagnosis and staging of patients with suspected acute diverticulitis is often made by CT imaging with intravenous contrast, which involves radiation exposure, is expensive and has contraindications. The aim of this study is to evaluate the diagnostic accuracy and role of bedside abdominal US for the diagnosis of acute diverticulitis

NCT ID: NCT03262025 Completed - Laparotomy Clinical Trials

Primary Cecal Pathologies Presenting as Acute Abdomen

Start date: January 1, 2016
Phase: N/A
Study type: Observational

Background: The importance of cecal pathologies lie in the fact that being the first part of large intestine, any disease involving the cecum affects overall functioning of the large bowel. Primary cecal pathologies presenting as acute abdomen have not been described in any previous study in terms of presentation, management and outcome. Objectives: The objective of this study was to identify the reported causes of primary cecal pathologies presenting as acute abdomen and the various causes presenting in Indian setting, to discuss morbidity and mortality associated with cecal pathologies and to critically analyse the various management modalities employed in emergency setting.

NCT ID: NCT03146091 Completed - Clinical trials for Uncomplicated Diverticular Disease

Outpatient Treatment of Uncomplicated Diverticulitis With Either Antibiotic or Nonantibiotic Treatment

MUD
Start date: May 20, 2017
Phase: N/A
Study type: Interventional

Uncomplicated sigmoid diverticulitis is a common disease in Western countries. Traditional management includes inpatient administration of either oral or intravenous antibiotics with resumption of oral intake as symptoms improve. Recent literature has however questioned both inpatient and antibiotic treatment. Indeed, both inpatient and antibiotic treatment are associated with non-negligible risks to patients. The aim of this trial is to assess the feasibility of a randomized controlled trial designed to determine whether nonantibiotic treatment of uncomplicated diverticulitis is safe in the outpatient setting.

NCT ID: NCT03143517 Completed - Ulcerative Colitis Clinical Trials

Fecal Calprotectin Collection Protocol

CALFE
Start date: April 19, 2017
Phase:
Study type: Observational

The primary objective is to obtain stool samples from subjects diagnosed with , and displaying signs and/or symptoms of IBD and/or IBS will be evaluated in this study. Eligible subjects require a diagnostic colonoscopy with possible biopsy and clinical evaluation.

NCT ID: NCT03042091 Recruiting - Clinical trials for Inflammatory Bowel Diseases

Neomycin and Metronidazole Hydrochloride With or Without Polyethylene Glycol in Reducing Infection in Patients Undergoing Elective Colorectal Surgery

Start date: September 2016
Phase: Early Phase 1
Study type: Interventional

This randomized clinical trial studies how well neomycin and metronidazole hydrochloride with or without polyethylene glycol work in reducing infection in patients undergoing elective colorectal surgery. Polyethylene glycol, may draw water from the body into the colon, flushing out the contents of the colon. Antibiotics, like neomycin and metronidazole hydrochloride, may stop bacteria from growing. It is not yet known whether it's better to give preoperative neomycin and metronidazole hydrochloride with or without polyethylene glycol in reducing surgical site infection after colorectal surgery.