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Dietary Exposure clinical trials

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NCT ID: NCT05842460 Completed - Dietary Exposure Clinical Trials

Testing "Ultraprocessed" Front-of-package Label Among Brazilian Consumers

Start date: May 24, 2023
Phase: N/A
Study type: Interventional

The goal of this experiment is to test the effects an "ultraprocessed" warning label on foods and beverages among Brazilian consumers. The main questions it aims to answer are: - Do "ultraprocessed" warnings affect Brazilian consumers' intention to purchase products? - Do "ultraprocessed" warnings affect Brazilian consumers' product perceptions? Participants will see images of four products carrying either nutrient warning labels (which are currently mandatory in Brazil) or nutrient warning labels alongside an experimental warning label informing that the product is ultraprocessed. Participants will then answer survey questions about each product. Researchers will compare responses between both arms to determine if the "ultraprocessed" warning significantly changes the effect of nutrient warnings.

NCT ID: NCT05763992 Recruiting - Breast Cancer Clinical Trials

Targeting Triple Negative BREAst Cancer Metabolism With a Combination of Chemoimmunotherapy and a FASTing-like Approach in the Preoperative Setting: the BREAKFAST 2 Trial

BREAKFAST-2
Start date: May 15, 2023
Phase: Phase 2
Study type: Interventional

Italian, multicenter, open-label, two-arm, comparative, randomized phase II study investigating if the addition of the experimental metabolic intervention consisting in cycles of Fasting-Like Approach, as administered every three weeks up to a maximum of 8 consecutive cycles, is able to increase the anticancer activity of standard preoperative chemo-immunotherapy in patients with localized invasive Triple Negative Breast Cancer.

NCT ID: NCT05668832 Not yet recruiting - Safety Issues Clinical Trials

Bioavailability of Vitamin D Photoisomers From UVB-exposed Button Mushrooms

Start date: January 9, 2023
Phase: N/A
Study type: Interventional

The European Food Safety Authority has approved many applications for UVB light treated foods (e.g. UVB-exposed button mushrooms) in the last years. The UVB light treatment is used to increase the vitamin D content in foods and improve the vitamin D status of subjects. However, UVB irradiation is accompanied by the formation of vitamin D photoisomers such as lumisterol and tachysterol. The current study aims to investigated whether these vitamin D photoisomers can enter the circulation and are metabolised in humans that consume UVB-treated mushrooms.

NCT ID: NCT05549622 Recruiting - Sarcopenia Clinical Trials

Impact of Diet on the Gut-Muscle Axis in Older Adults

Start date: March 1, 2023
Phase: N/A
Study type: Interventional

Muscle health declines during aging. One factor that may impact muscle health is the community of bacteria that live in our intestines, but studies aimed at improving muscle health by targeting the gut in older adults are sparse. The primary goal of this study is to use a diet that is enriched in soluble fiber, which is exclusively utilized by gut bacteria to make substances that can impact muscle health, to improve muscle-related measures in older adults.

NCT ID: NCT05455164 Completed - Dietary Exposure Clinical Trials

The Effect of Eucaloric High-Protein Fiber Diet in Healthy Adults: A Repeated Single-Arm Clinical Trial

Start date: January 1, 2020
Phase: N/A
Study type: Interventional

The aims of this study is to investigate the effect of eucaloric high protein and fiber diet on healthy subjects.

NCT ID: NCT05002491 Completed - Dietary Exposure Clinical Trials

Change in Leptin as a Predictor of Satiety With High Protein Feeding

HiProLep
Start date: May 1, 2002
Phase: N/A
Study type: Interventional

Body weight can be affected by the content of fat and carbohydrate in the diet. On average, people will lose a modest (< 5 kg) amount of weight when switched from a high fat diet to a low fat, high carbohydrate diet. Determining mechanisms whereby changing the makeup of the diet can change one's body weight will be important in understanding why body weight in the US population is trending upward recently and what health care providers can recommend to reverse this trend. Previous studies have shown that increasing the carbohydrate and lowering the fat content in the diet leads to a change in the appearance of the hormone leptin in the blood over 24 hours. Leptin is an important signal from the fat cell to the brain that leads to a reduction in appetite and weight loss. A previous study found that after keeping people's weight stable, that the greater rise in leptin over the day on a low fat-high carbohydrate diet compared to a high fat diet predicted the reduction in calories they ate over a subsequent 12 weeks when their weight was allowed to freely fluctuate. Recent studies have also provided evidence that limiting fat and increasing the amount of protein in the diet also leads to modest weight loss. It is therefore proposed to test whether low fat, high protein diets also result a change in leptin secretion, and if this change predicts a reduction in appetite when they are allowed to eat freely.

NCT ID: NCT04963842 Completed - Dietary Exposure Clinical Trials

Investigation on the Benefits of Avoiding Conventional Food Packaging and Promoting Bioplastic Food Packaging

BIOFOODPACK
Start date: July 15, 2021
Phase: N/A
Study type: Interventional

A trial study was proposed as part of the project "Biocomposite Packaging for Active Preservation of Food" (acronym BIOFOODPACK) that has been funded by the M-ERA.Net Call 2016. A crossover trial with a behavioral intervention study will be conducted. The behavioural intervention treatment consists of: i) avoiding the consumption of packaged (cans, plastic, paper) ready to consume foods, and foods from take away/delivery/fast food, and ii) using the proposed bio-based packaging material to package foods ready for consumption; this bio-based packaging material (Silvex Ltd, Portugal) does not contain plasticizers, it is biodegradable and made out of plant-based materials (corn, starch, etc.). The objectives of this study are: 1. To describe the body burden of plasticizers for women aged 18-40 years systematically adopting the intervention treatment package during the 5-day period. 2. To assess the diurnal variability of the plasticizers, based on regular daily activities of the young adult women.

NCT ID: NCT04887610 Completed - Dietary Exposure Clinical Trials

Factors That Influence Blood Vessel Regulation During Exercise in Humans

Start date: May 20, 2021
Phase: N/A
Study type: Interventional

This study will examine two separate interventions: 1) the effects of ischemic preconditioning or 2) a high fat meal on the capacity of the brachial artery to overcome sympathetic activation and dilate during exercise (also known as functional sympatholysis). Participants will be asked to complete rhythmic handgrip exercise with and without the application of -20 mmHg lower body negative pressure to increase sympathetic activation. Doppler ultrasound will be used to continuously measure brachial artery blood flow. Participants will complete the handgrip exercise and lower body negative pressure before and after the applications of each interventions. Participants may elect to only complete one intervention rather than complete both protocols. Intervention one is active or control ischemic preconditioning. Intervention two is high or low fat meals.

NCT ID: NCT04840160 Completed - Clinical trials for Metabolic Disturbance

Influence of Tart Cherry Juice Intervention on Vascular Function

Start date: April 1, 2016
Phase: N/A
Study type: Interventional

Diets containing fruit rich in anthocyanins have been shown (in meta-analyses) to be beneficial for health, but intervention trials have shown inconsistent results. In this preliminary study we want to investigate the influence of a tart-cherry juice intervention on vascular function and explore metabolite profiles that may offer insight into their mechanism of action

NCT ID: NCT04518930 Completed - Body Weight Clinical Trials

High Fat vs High Protein and Appetite Hormones

Start date: May 1, 2020
Phase: N/A
Study type: Interventional

This study will investigate the effects of high-protein, high-fat snacks, specifically Greek yogurt, and peanuts, on satiety, gut hormones, and insulin secretion in overweight and obese women. The hypothesis posited that peanuts will exhibit a more beneficial impact on satiety, gut hormones, and insulin levels compared to Greek yogurt. The two-arm parallel randomized trial will involve 52 participants aged 30 to 40 with a BMI between 25-35 kg/m²,and they will be randomly divided into peanut (n=26) and Greek yogurt (n=26) groups. Pre-snack, BMI and dietary intake will be assessed. Appetite sensations will be gauged using a visual analog scale (VAS) upon arrival, and at 30- and 60-minutes post-snack. Pre- and post-snacking, plasma levels of cholecystokinin (CCK), Peptide Tyrosine-Tyrosine (PYY), Glucagon Like Peptide-1 (GLP-1), Ghrelin (GHRL), and insulin will be analyzed.