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Diarrhea clinical trials

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NCT ID: NCT00937274 Terminated - Diarrhea Clinical Trials

Antibacterial Treatment Against Diarrhea in Oral Rehydration Solution

Start date: August 2009
Phase: N/A
Study type: Interventional

This study hopes to demonstrate the potentials of a new form of therapy for childhood diarrhea, a major cause of morbidity and deaths in Bangladesh and other developing countries, and thus a priority for improving child health.

NCT ID: NCT00732732 Terminated - Diarrhea, Infantile Clinical Trials

A Controlled Trial of Plantain Powder in Infantile Diarrhea

Start date: September 2008
Phase: N/A
Study type: Interventional

Green banana has been traditionally used in diarrheal and other diseases. Recent studies have shown that green banana is beneficial in children with diarrhea. The purpose of this study is to try green banana in a portable, storable and dosable form in infants with diarrhea. Infants with diarrhea and meeting the inclusion criteria will receive either green banana powder or placebo (microcrystalline cellulose). Their response will be monitored for 10 days. The subjects, parents and researchers conducting the study will not know whether banana powder or placebo is being given to that particular subject (double blind randomized study). Two hundred patients will be enrolled in 24 months.

NCT ID: NCT00650637 Terminated - Diarrhea Clinical Trials

A Study to Determine Effective Prophylaxis and Treatment of Nelfinavir-Associated Diarrhea

Start date: January 2003
Phase: Phase 3
Study type: Interventional

The purpose of this study was to determine the efficacy and safety of calcium carbonate for the prevention of nelfinavir-associated diarrhea and to evaluate the efficacy and safety of calcium carbonate in combination with loperamide for the treatment of nelfinavir-associated diarrhea.

NCT ID: NCT00624975 Terminated - Diarrhea Clinical Trials

Safety and Immunogenicity of Peru-15 Vaccine When Given With Measles Vaccine in Healthy Indian and Bangladeshi Infants

Start date: November 2008
Phase: Phase 2
Study type: Interventional

The purpose of this study is to confirm the safety and immunogenicity of Peru-15 vaccine in infants when given simultaneously with measles vaccine.

NCT ID: NCT00466635 Terminated - Diarrhea Clinical Trials

A Study to Assess the Safety, Tolerability, Effectiveness and Absorption of Exodif™ Tablets in Clostridium Difficile-associated Diarrhea

Start date: April 2007
Phase: Phase 3
Study type: Interventional

Approximately 65 patients will be entered into this study taking place in North America. The aim of this study is to evaluate the safety, efficacy and absorption of an investigational drug in patients with C. difficile-associated diarrhea (CDAD). All study related care is provided including doctor visits, physical exams, laboratory tests and study medication. Total length of participation is 6 weeks.

NCT ID: NCT00444093 Terminated - Cancer Clinical Trials

Prospective Randomized Open Label Study of the Treatment of Therapy-associated Diarrhea During Percutaneous Radiation Therapy of the Small Pelvis. - Comparison of Loperamide and Tincture of Opium -

Loop
Start date: March 5, 2007
Phase: Phase 3
Study type: Interventional

Therapy-associated diarrhea during radiation therapy of small pelvis (including enteritis as a result of radiation therapy and enteritis as a result of radiation- and chemotherapy) is a common problem in multimodal cancer therapy. We investigate the therapeutic effect of either loperamide or tinctura opii in therapy- associated diarrhea in patients who receive radiation therapy of the small pelvis with or without chemotherapy.

NCT ID: NCT00219505 Terminated - Clinical trials for Irritable Bowel Syndrome

Effect of Acupuncture on Symptoms of Diarrhea and Pain in IBS

Start date: August 2001
Phase: N/A
Study type: Interventional

Acupuncture has been used for centuries in China in the treatment of diarrhea. Our hypothesis is that acupuncture is effective in the treatment of abdominal pain and diarrhea in patients with diarrhea-predominant IBS

NCT ID: NCT00217022 Terminated - Diarrhea Clinical Trials

Budesonide Versus Placebo for the Treatment of Lymphocytic Colitis

Start date: June 2003
Phase: Phase 2/Phase 3
Study type: Interventional

Patients will receive budesonide or placebo for the treatment of active lymphocytic colitis. This study includes stool collections, blood draws, weekly questionnaires and a sigmoidoscopy. The study hypothesis is that budesonide will be safe and effective compared with placebo for the treatment of diarrhea in lymphocytic colitis.

NCT ID: NCT00179582 Terminated - IBS Clinical Trials

Dose Ranging Study With the Probiotic Combination (VSL#3) in Diarrhea IBS

Start date: January 2005
Phase: N/A
Study type: Interventional

To evaluate the effects of VSL#3 on symptoms associated with diarrhea predominant IBS

NCT ID: NCT00177970 Terminated - Clinical trials for Clostridium Difficile-associated Diarrhea (CDAD)

IVIG Versus Placebo for the Treatment of Patients With Severe C-Diff

Start date: October 2003
Phase: Phase 4
Study type: Interventional

In this trial, eligible patients will be randomly assigned to receive a single dose of 400 mg/kg of IVIG or a normal saline infusion as placebo over 4-6 hours, in addition to their usual medications for CDAD. We expect to enroll approximately 40 patients over a period of two years from UPMC Shadyside Hospital, McKeesport Hospital, and St. Margaret's Hospital who are unresponsive to standard antimicrobial therapy for CDAD. During the course of this study we expect that IVIG group compared with placebo group will have fewer number of stools per day (< 3 per day). Secondary endpoints will include normal WBC count, normal body temperature, 75% reduction in abdominal pain / tenderness, and decrease in length of hospital stay. Subjects will sign a written informed consent prior to any study procedures. Patients will be monitored closely during the infusion of the study medication and will continue to be monitored on a daily basis up to the time of discharge. Data collection will include vital signs, CBC, stool C. difficile cytotoxin assay, and stool counts before and after therapy.