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Diarrhea clinical trials

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NCT ID: NCT02320318 Withdrawn - Clinical trials for Irritable Bowel Syndrome With Diarrhea

12-Week Efficacy and Safety Study of Ibodutant in Women With Irritable Bowel Syndrome With Diarrhea (IBS-D)

IRIS-05
Start date: October 2015
Phase: Phase 3
Study type: Interventional

Irritable Bowel Syndrome with diarrhoea (IBS-D) is a functional gastrointestinal disorder characterised by chronic or recurrent abdominal pain or discomfort and diarrhoea. The aim of this trial is the evaluation of the efficacy and safety of oral ibodutant 10 mg once daily as compared to placebo in women with IBS-D over a 12-week treatment period.

NCT ID: NCT02111304 Withdrawn - Secretory Diarrhea Clinical Trials

Efficacy of iOWH032 in Dehydrating Cholera

POC
Start date: June 2014
Phase: Phase 2
Study type: Interventional

The primary hypothesis is that administration of iOWH032 to adult and pediatric males and females with acute cholera due to V. cholerae O1 reduces stool output in the first 24 hours significantly more than does the current standard of care.

NCT ID: NCT02080130 Withdrawn - Gastroenteritis Clinical Trials

Efficacy of Two Probiotic Preparations in Children With Acute Diarrhoea

Start date: February 2014
Phase: N/A
Study type: Interventional

The purpose of this study is to determine which of two different preparations of probiotics is effective in the treatment of acute viral diarrhoea in children.

NCT ID: NCT01644097 Withdrawn - Clinical trials for Unspecified Adult Solid Tumor, Protocol Specific

Probiotic Supplementation in Preventing Treatment-Related Diarrhea in Patients With Cancer Undergoing Chemotherapy

Start date: November 2012
Phase: Phase 2
Study type: Interventional

This randomized phase II clinical trial studies probiotic supplementation in preventing treatment-related diarrhea in patients with cancer undergoing chemotherapy. Probiotics may help prevent diarrhea caused by treatment with chemotherapy.

NCT ID: NCT01596153 Withdrawn - Clinical trials for Antibiotic Associated Diarrhea

Probiotics in Hospitalized Patients Study

Start date: n/a
Phase: N/A
Study type: Interventional

The purpose of this study is to compare the effect of enhanced probiotic (EP, Live Rx) versus placebo (PL) on the incidence of Clostridium difficile associated diarrhea (CDAD) or antibiotic associated diarrhea (AAD) in hospitalized patients initiated on antibiotics.

NCT ID: NCT01473290 Withdrawn - Fatigue Clinical Trials

Probiotic Therapy in Preventing Gastrointestinal Complications in Patients Undergoing Chemotherapy and Pelvic Radiation Therapy

Start date: n/a
Phase: Phase 3
Study type: Interventional

RATIONALE: Probiotic therapy may reduce or prevent gastrointestinal complications in patients undergoing chemotherapy and pelvic radiation therapy. PURPOSE: This randomized phase III trial is studying how well probiotic therapy works in preventing gastrointestinal complications in patients undergoing chemotherapy and pelvic radiation therapy.

NCT ID: NCT01463943 Withdrawn - Antibiotics Clinical Trials

Non-Inferiority Trial Comparing Eurofarma's Experimental Product Saccharomyces Boulardii Versus Floratil® in the Prevention of Antibiotic-Associated Diarrhea

ACROSS
Start date: February 2012
Phase: Phase 3
Study type: Interventional

The study's objective is to evaluate the efficacy and safety of two formulations for the prophylactic treatment of diarrhea in subjects using antibiotics.

NCT ID: NCT01114113 Withdrawn - Clinical trials for Irritable Bowel Syndrome

Assessment of Gastric Emptying Speed in Patients Who Experience Diarrhea Following a Trigger Meal

Start date: April 2010
Phase: N/A
Study type: Interventional

The rapid diarrhea that patients experience who have diarrhea occurring after eating specific foods may be causing a "physiologic gastric dumping syndrome". This means that rather than the food being kept in the stomach for normal digestion, it rapidly goes into the small intestine and diarrhea occurs. This study is designed to measure how fast the food empties from the stomach when a person with this problem consumes a "regular diet", compared to a meal with a "triggering substance". Each participant will swallow a radio frequency capsule that with the different meals that will show how fast the food is traveling through the intestines in the different situations.

NCT ID: NCT00875875 Withdrawn - Travelers' Diarrhea Clinical Trials

Single Daily Dose Rifaximin for the Treatment of Travelers' Diarrhea

Rifaximin 600
Start date: June 2009
Phase: Phase 4
Study type: Interventional

The study will compare durations of diarrhea among subjects who report to clinic for treatment and who receive either: 1. standard rifaximin therapy at a dose of 200 mg three times a day for 3 days, OR 2. a single 600 mg dose of rifaximin daily for 3 days.

NCT ID: NCT00338221 Withdrawn - Clinical trials for Diarrhea, Malnutrition

Clinical Trial of Alanyl-Glutamine or Glycine in Children With Persistent Diarrhea or Malnutrition

Start date: August 2004
Phase: Phase 3
Study type: Interventional

This is a double blinded randomized clinical trial of Alanyl-Glutamine or Glycine in children with persistent diarrhea or malnutrition. The primary objective of the study is to determine the effect of 7 days of supplementation of alanyl-glutamine as it compares to glycine on the damaged intestinal barrier function, measured by lactulose/mannitol test on day 8, in children at HIAS in Fortaleza, Ce, Brazil, with persistent diarrhea (history > 2 weeks duration) or malnutrition.