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Diaphragm Issues clinical trials

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NCT ID: NCT06257589 Active, not recruiting - Clinical trials for Diaphragmatic Paralysis

A Chart Review to Evaluate the Safety and Efficacy of Phrenic Nerve Reconstruction for the Treatment of Diaphragmatic Paralysis

Start date: October 10, 2023
Phase:
Study type: Observational

A retrospective chart review to evaluate the safety and efficacy of phrenic nerve reconstruction for diaphragmatic paralysis.

NCT ID: NCT05951114 Recruiting - Neurosurgery Clinical Trials

Post-neurosurgical Respiratory Muscle Dysfunction

Start date: July 1, 2023
Phase:
Study type: Observational

Respiratory muscle dysfunction may contribute to the development of postoperative pulmonary complications. However, it prevalence in patients receiving neurosurgery is largely unknown. Therefore, in present study, respiratory muscle function (measured by the ultrasound) and their correlation with the post-operative pulmonary complications will be analyzed.

NCT ID: NCT05883163 Recruiting - Diaphragm Issues Clinical Trials

STIMIT Activator 1 IDE Pivotal Study

Start date: November 7, 2023
Phase: N/A
Study type: Interventional

The study is a prospective, multi-center, randomized, controlled study using adaptive design to assess the evidence of safety and performance of the STIMIT Activator 1 System in the treatment of patients who have been mechanically ventilated for up to 48 hours and are predicted to require additional minimum 48 hours of mechanical ventilation or longer (adding up to MV time approximately 96 hours or longer).

NCT ID: NCT05833243 Completed - GERD Clinical Trials

Effectiveness of Modified Diaphragmatic Training for Gastroesophageal Reflux Disease Post Covid-19

Start date: February 8, 2023
Phase: N/A
Study type: Interventional

The study titled "Effectiveness of Modified Diaphragmatic Training for Improving GERD-Q Score, Diaphragmatic Excursion, Maximum Inspiratory Pressure and Lung Function in Adults With Gastroesophageal Reflux Disease After Covid-19: a Single-blinded Randomized Control Trial" is a clinical trial that aimed to investigate the effectiveness of 4 weeks modified diaphragmatic training (MDT) compare with standard diaphragmatic training for improving GERD-Q score, diaphragmatic excursion, maximum inspiratory pressure, and lung function in adults with gastroesophageal reflux disease (GERD) after COVID-19. The trial was single-blinded and randomized, and it included a total of 50 participants. The results of the study showed that MDT was effective in improving GERD-Q score, diaphragmatic excursion, maximum inspiratory pressure, and lung function in adults with GERD after COVID-19.

NCT ID: NCT05787626 Not yet recruiting - Healthy Clinical Trials

Efficacy of the Transverse Planes Technique in the Diaphragmatic Region in Young Subjects.

Start date: April 1, 2023
Phase: N/A
Study type: Interventional

In the present study, 28 healthy young people will be selected, who will be evaluated by a blind investigator regarding the study objectives, and will be randomly included in two groups. The experimental group will consist of 14 subjects who will carry out 1 weekly session of 10 minutes and who will be evaluated just before starting the intervention, after it and at 4 weeks. The control group will be made up of 14 subjects who will be evaluated in the three periods described without the need to carry out the intervention.

NCT ID: NCT05748522 Completed - Shoulder Pain Clinical Trials

Functional Movement Analysis (FMS) of Diaphragmatic Breathing-Immediate Effect on Shoulder Mobility

Start date: October 12, 2022
Phase: N/A
Study type: Interventional

The diaphragm is defined as a thin, smooth muscle that separates the thoracic and abdominal cavities. The shoulder and diaphragm muscle have a clear relationship through innervation and myofascial tissue connection. Fascia is often neglected medically, rehabilitatively, or performance as the underlying cause of problems. Bones, organs, and muscles appear to float in the fascial web, a continuous three-dimensional system of connective tissue. Plastic and viscoelastic properties, which can change tension and shape under the influence of manual techniques and movement retraining, ensure that the structural changes are reversible. Functional Movement Analysis (FMS) is a screening system that aims to predict the risk of injury and functional deficiencies. FMS consists of 7 basic motion component tests. It is scored on a scale of zero to three and creates a composite score whose sum ranges from 0 to 21 points. One of the 7 motion models evaluated is shoulder mobility. According to the results of this study, people who perform activities that require shoulder mobility will be guided as to whether the use of diaphragmatic breathing will be effective for preparation, rehabilitation or performance improvement. The aim of the study was to observe whether shoulder mobility increased in healthy individuals taught diaphragm breathing compared to the control group.

NCT ID: NCT05670327 Completed - Weakness, Muscle Clinical Trials

Diaphragmatic Ultrasound and Weaning After Lung Transplant.

Start date: June 22, 2021
Phase:
Study type: Observational

The prevalence and adverse effect of diaphragm dysfunction (DD) after bilateral-lung transplant (LT) are still unclear, despite a well-known negative impact on weaning and outcome in other cohorts of critically ill and surgical patients. Objects: The primary aim is investigating the prevalence of DD, assessed using point-of-care ultrasound and defined as diaphragm thickening fraction (TFdi) < 29%, at the first weaning trial after LT. Secondary aims are investigating the impact of DD on weaning (defined success or failure according to pre-defined criteria, neuroventilatory efficiency (EAdi or NVE), perioperative (14-day) pneumonia, ICU length of stay (LOS), in-hospital mortality, and identifying potential risk factors for DD. Moreover, we aim to study the correlation between TFdi versus EAdi/NVE and the rapid shallow breathing index (RSBI), respectively.

NCT ID: NCT05211661 Recruiting - Respiratory Failure Clinical Trials

Diaphragm Atrophy and Dysfunction in Mechanical Ventilation

DAM
Start date: October 10, 2022
Phase:
Study type: Observational

The gold standard of twitch transdiaphragmatic pressure recordings would ultimately clear the fog around the rate of development of Ventilator induced Diaphragm Dysfunction (VIDD) in mechanically ventilated patients over time. Through measurements made even after mechanical ventilation (MV) it could be clarified to what extent patients recover from VIDD. Paired with cortical stimulation and electromyographic recordings of diaphragm muscle potentials, it could be explored to what extent decreased diaphragm excitability due to long term MV contributes to VIDD on the level of motor cortex. Against that background the present project aims at determining the rate of decline in diaphragm function, strength and control in patients undergoing MV (including measurements after extubation).

NCT ID: NCT05128552 Completed - Clinical trials for Mechanical Ventilation Complication

Effect of Lung Volume Recruitment Technique After Extubation

Start date: December 15, 2020
Phase: N/A
Study type: Interventional

This study was conducted to investigate the effect of the LVR technique on cough ineffectiveness, to determine its benefit as a simple, safe, and inexpensive cough augmentation technique, and to determine how much the LVR method, for augmenting CPF, is useful in enhancing the success of extubation and reducing the rate of reintubation.

NCT ID: NCT04962568 Recruiting - Diaphragm Issues Clinical Trials

Ultrasonographic Evaluation of the Diaphragm During NHF Versus NIV Use in Respiratory Failure

SENNI
Start date: July 7, 2021
Phase: N/A
Study type: Interventional

This study will describe influence of NHF or NIV to different ultrasonographic parameters of the diaphragm. Therefor subjects will be randomized to the sequence NHF and than NIV or NIV and than NHF. In all subjects same parameters will be evaluated.