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Clinical Trial Summary

Resting tremors associated with Parkinson's disease (PD) remains difficult to quantify and track during disease progression. This study propose to explore the rhythmicity of distal muscle contractions in the upper limb to characterize resting tremor and discriminate it from cerebellar tremor (CT) based on the frequency spectrum of the EMG signal.


Clinical Trial Description

This retrospective study analyzed surface EMG recordings of wrist flexor-pronators and extensor-supinators from patients with PD or CT bilaterally in five 10-second conditions: rest with contralateral motor distraction, symmetrical arms extended forward posture with hands pronated, semi-pronation, supination, and elbows flexed with hands pronated. The rhythmicity index (RI) is calculated from the ratio of the area of the maximum power peak to the total area of the spectrum between 1.5-12Hz. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05998486
Study type Observational
Source Henri Mondor University Hospital
Contact Emilie Hutin, PhD
Phone +33149812549
Email emilie.hutin@aphp.fr
Status Recruiting
Phase
Start date April 3, 2023
Completion date December 31, 2023

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