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NCT06329882 Clinical Trial

Doxycycline in Type II Diabetes

Diabetes Mellitus, Type 2 Clinical Trial

Official title:
Doxycycline in Combination With Sitagliptin on the Glycemic and Cardiac Indices in Patients With Type 2 Diabetes Mellitus

Clinical Trial Details — Status: Not yet recruiting

Administrative data
NCT number NCT06329882
Other study ID # 14789
Secondary ID
Status Not yet recruiting
Phase Phase 1/Phase 2
First received
Last updated
Start date March 30, 2024
Est. completion date April 20, 2025

Study information
Verified date March 2024
Source Tanta University
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Type 2 diabetes mellitus (T2DM) is a chronic metabolic disease characterized by hyperglycemia, weight loss, and cardio-metabolic complications. T2DM develops due to the progression of insulin resistance (IR), impairment of insulin insensitivity, and failure of the pancreatic β-cells to release sufficient amount of insulin in response to glucose burden

Recruitment information / eligibility
Status Not yet recruiting
Enrollment 60
Est. completion date April 20, 2025
Est. primary completion date March 20, 2025
Accepts healthy volunteers No
Gender All
Age group 40 Years to 60 Years
Eligibility Inclusion Criteria: - Male or female sex more than 40 years old Newly diagnosed type II diabetes. HbA1c more than 6.5 Exclusion Criteria: - Patient with chronic kidney disease, hepatic disorders, mental and psychiatric disorders, pregnancy, and lactation

Study Design

Related Conditions & MeSH terms

Intervention

Drug:
• Sitagliptin 100mg
Sitagliptin is used along with diet and exercise and sometimes with other medications to lower blood sugar levels in adults with type 2 diabetes
• Doxycyclin
Doxycycline belongs to the class of medicines known as tetracycline antibiotics. It works by killing bacteria or preventing their growth.

Locations
Country Name City State
n/a

Sponsors (1)
Lead Sponsor Collaborator
Mostafa Bahaa

Outcome
Type Measure Description Time frame Safety issue
Primary Change in glycemic profile measurement of fasting blood glucose (FBG) 3 months
Primary Change in glycemic profile measurement of glycated hemoglobin 3 months
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