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NCT05048264 Clinical Trial

Effect of Corticosteroid Injections on Blood Glucose

Diabetes Mellitus Clinical Trial

— CSI  

Official title:
Corticosteroid Injections Administered Under Ultrasound Guidance to Diabetic Patients and the Effect on Blood Glucose

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT05048264
Other study ID # Pro00108093
Secondary ID
Status Recruiting
Phase
First received
Last updated
Start date May 4, 2023
Est. completion date October 25, 2024

Study information
Verified date May 2023
Source Duke University
Contact Duke Sports Medicine Research
Phone 9196842042
Email sportsmed_research@dm.duke.edu
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The purpose of this study is to measure the effect of various corticosteroids administered to the shoulder, knee and hip joints in diabetic patients on resultant blood glucose readings.

Description:

The purpose of this study is to measure the effect of various corticosteroids administered to the shoulder, knee, and hip joints in diabetic patients on resultant blood glucose readings. Corticosteroid injections (CSI) are frequently used in orthopedic settings in order to treat a wide array of orthopedic issues, including osteoarthritis, bursitis, tendinitis, and many others. The effect of diabetes on the musculoskeletal system and its role in orthopedic disease has been well-documented. Current evidence demonstrates that corticosteroids, even when administered through a local musculoskeletal injection, can lead to temporary increases in blood glucose. Ultrasound guidance was not explicitly used in any of the studies examining the impact of steroids on blood glucose. The utilization of ultrasound guidance has been shown to increase accuracy when performing injections into the subacromial space as well as the glenohumeral joint when compared to palpation/landmark-guided injections.

Recruitment information / eligibility
Status Recruiting
Enrollment 55
Est. completion date October 25, 2024
Est. primary completion date October 11, 2024
Accepts healthy volunteers No
Gender All
Age group 40 Years to 75 Years
Eligibility Inclusion Criteria: - Known diabetic patients ages 40-75 undergoing clinically indicated standard of care corticosteroid shoulder, knee and hip joint injection - Ability to perform daily blood glucose testing - Can receive and send text messages Exclusion Criteria: - Previous joint arthroplasty - Corticosteroid injection at other sites in the body within the past month - Systemic corticosteroid within the last month other than asthma inhaler - Anyone who are unable to read and/or understand English - Pregnant women (self-report)

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
United States Duke Sports Science Institute Durham North Carolina

Sponsors (1)
Lead Sponsor Collaborator
Duke University

Country where clinical trial is conducted

United States, 

Outcome
Type Measure Description Time frame Safety issue
Primary Change in blood glucose measures Reported daily glucose measures from baseline to two week after injection Baseline & 2 weeks
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