Effects of Home-based Resistance Exercise on Body Composition, Muscle Strength and Glycemic Control in People With Type 2 Diabetes.

Diabetes Clinical Trial

Official title:

Effects of Home-based Resistance Exercise on Body Composition, Muscle Strength and Glycemic Control in People With Type 2 Diabetes.

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04136730
• Other study ID #: HM-2019-021
• Status: Completed
• Phase: N/A
• Start date: August 1, 2019
• Est. completion date: December 1, 2021

Study information

• Verified date: December 2021
• Source: Dasman Diabetes Institute
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This study investigates the effects of home-based resistance exercise training, compared to a control group, on body composition, muscle strength and glycaemic control in people with type 2 diabetes.

Half participants will be in the home-based exercise group and half in the control group.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 126
• Est. completion date: December 1, 2021
• Est. primary completion date: December 1, 2021
• Accepts healthy volunteers: No
• Gender: All
• Age group: 21 Years and older

Eligibility

Inclusion Criteria:

• Physician diagnosed type 2 diabetes

• No changes in anti-diabetic medication in the last 3 months

Exclusion Criteria:

• Not currently or in the past year participating in any vigorous aerobic activity (>1h per week) or any resistance exercise.

• BMI of 45 or higher

• Blood pressure of 160/100mmHg or higher

• Currently receiving insulin therapy

Related Conditions & MeSH terms

• Diabetes
• Diabetes Mellitus

Intervention

Behavioral:
• Home-based
Resistance exercise carried out unsupervised at home

Locations

Country	Name	City	State
Kuwait	Dasman Diabetes Institute	Kuwait City

Sponsors (2)

Lead Sponsor	Collaborator
Dasman Diabetes Institute	University of Glasgow

Country where clinical trial is conducted

Kuwait, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Other	Grip strength	Grip strength measured by handheld dynamometer	Change from baseline to 32 weeks
Other	One rep max	The maximum weight that can be lifted for a single repetition of leg extension and lateral pull down	Change from baseline to 32 weeks
Other	Push up test	Number of push ups that can be performed	Change from baseline to 32 weeks
Other	BMI	Body mass index	Change from baseline to 32 weeks
Other	Body fat	Total body fat measured via DEXA	Change from baseline to 32 weeks
Other	Visceral fat	Visceral adipose tissue measured by DEXA	Change from baseline to 32 weeks
Other	Physical activity levels	Physical activity levels measured with a wrist worn accelerometer	Change from baseline to 32 weeks
Other	Quality of life score	EQ-5D-DL questionnaire will be used (5 (worst) to 125 (best))	Change from baseline to 32 weeks
Primary	Glycated Haemoglobin concentration (mmol/mol)	Glycated haemaglobin	Change from baseline to 32 weeks
Secondary	Fat-free mass	Whole body fat free mass	Change from baseline to 32 weeks
Secondary	Short performance physical battery test	Short performance physical battery test (0 (worst performance) to 12 (best performance))	Change from baseline to 32 weeks