Outcome
Type |
Measure |
Description |
Time frame |
Safety issue |
Primary |
Wide Range Achievement Test 4 (WRAT 4) |
Word reading subtest to measure letter and word decoding through word recognition and letter identification. This outcome is a data pull/chart review from a previous study for some of the participants.Score range is 0-70, 70 is the best score possible. |
up to 25 years prior to Day 1 |
|
Primary |
Wide Range Achievement Test 4 (WRAT 4) |
Word reading subtest to measure letter and word decoding through word recognition and letter identification. Score range is 0-70, 70 is the best score possible. |
Day 1 |
|
Primary |
Rey Auditory Verbal Learning Test (RAVLT) |
A word recall list that measures verbal learning and memory. Involves immediate and delayed recall. This outcome is a data pull/chart review from a previous study for some of the participants. Score range is 0-75, 75 is the best possible score. |
up to 25 years prior to Day 1 |
|
Primary |
Rey Auditory Verbal Learning Test (RAVLT) |
A word recall list that measures verbal learning and memory. Involves immediate and delayed recall. Score range is 0-75, 75 is the best possible score. |
Day 1 |
|
Primary |
Modified Mini-Mental State Exam (3MSE) |
Measures general cognitive function. This outcome is a data pull/chart review from a previous study for some of the participants. Score range is 0-100, 100 is the best possible score. |
up to 25 years prior to Day 1 |
|
Primary |
Modified Mini-Mental State Exam (3MSE) |
Measures general cognitive function. Score range is 0-100, 100 is the best possible score. |
Day 1 |
|
Primary |
Digit Symbol Coding Task (DSC) |
DSC is a subtest of the Wechsler Adult Intelligence Scale III or IV. It is used to access visual motor speed. This outcome is a data pull/chart review from a previous study for some of the participants. Score range 0-133, 133 is the best possible score. |
up to 25 years prior to Day 1 |
|
Primary |
Digit Symbol Coding Task (DSC) |
DSC is a subtest of the Wechsler Adult Intelligence Scale III or IV. It is used to access visual motor speed. Score range 0-133, 133 is the best possible score. |
Day 1 |
|
Primary |
Stroop subtests 1, 2 and 3 |
Measures executive function by determining interchanging word and color challenges. This outcome is a data pull/chart review from a previous study for some of the participants. Score range 0-420 seconds, the lower time point is the best. |
up to 25 years prior to Day 1 |
|
Primary |
Stroop subtests 1, 2 and 3 |
Measures executive function by determining interchanging word and color challenges. Score range 0-420 seconds, the lower time point is the best. |
Day 1 |
|
Primary |
Category Fluency for Animals |
Measures verbal fluency and language aspects of executive function by asking participant to name as many unique items as possible in a category ie. animals. This outcome is a data pull/chart review from a previous study for some of the participants. Score 0-26, the best possible score is 26. |
up to 25 years prior to Day 1 |
|
Primary |
Category Fluency for Animals |
Measures verbal fluency and language aspects of executive function by asking participant to name as many unique items as possible in a category ie. animals. Score 0-26, the best possible score is 26. |
Day 1 |
|
Primary |
Montreal Cognitive Assessments (MoCA) |
Measures general cognitive and executive function, has increased sensitivity for detecting early cognitive impairment.This outcome is a data pull/chart review from a previous study for some of the participants. Score range is 0-30, 30 is the best possible score. |
up to 25 years prior to Day 1 |
|
Primary |
Montreal Cognitive Assessments (MoCA) |
Measures general cognitive and executive function, has increased sensitivity for detecting early cognitive impairment.Score range is 0-30, 30 is the best possible score. |
Day 1 |
|
Secondary |
Craft Story Recall (Immediate/Delayed) |
Assesses the ability to retell a story from memory immediately and after a delay of approximately 20 minutes. Score 0-69 (for each portions of the test). The best possible score is 69. |
Day 1 |
|
Secondary |
Trail Making Test |
Measures processing speed and executive function. Part A- Score 0-150 sec, Part B Score 0-300 sec, the fastest time is better. |
Day 1 |
|
Secondary |
Number Span Test (Forward/Backward) |
Assesses working memory recalling numbers said forwards and backwards in increasing number of digits. Score 0-28, the best score possible is 28. |
Day 1 |
|